Zobrazeno 1 - 3
of 3
pro vyhledávání: '"V K, Rajwanshi"'
Publikováno v:
Chemistry (Weinheim an der Bergstrasse, Germany). 6(15)
We have used NMR and CD spectroscopy to study the conformations of modified oligonucleotides (locked nucleic acid, LNA) containing a conformationally restricted nucleotide (T(L)) with a 2'-O,4'-C-methylene bridge. We have investigated two LNA:RNA dup
Publikováno v:
Bioorganicmedicinal chemistry letters. 10(16)
Various Y-shaped branched oligonucleotides containing a 2'-0,3'-C-ethylene linked or 2'-0,4'-C-methylene linked bicyclic nucleotide as branching point were synthesized on an automated DNA synthesizer. Thermal denaturation experiments at 260 and 284 n
Autor:
M, Petersen, C B, Nielsen, K E, Nielsen, G A, Jensen, K, Bondensgaard, S K, Singh, V K, Rajwanshi, A A, Koshkin, B M, Dahl, J, Wengel, J P, Jacobsen
Publikováno v:
Journal of molecular recognition : JMR. 13(1)
We have used 2D NMR spectroscopy to study the sugar conformations of oligonucleotides containing a conformationally restricted nucleotide (LNA) with a 2'-O, 4'-C-methylene bridge. We have investigated a modified 9-mer single stranded oligonucleotide