Zobrazeno 1 - 10
of 52
pro vyhledávání: '"V K, Mazurik"'
Autor:
Zh M, Shagirova, L N, Ushenkova, V F, Mikhaĭlov, L A, Kurbatova, N S, Kuz'mina, A N, Semiachkina, I M, Vasil'eva, V K, Mazurik, G D, Zasukhina
Publikováno v:
Radiatsionnaia biologiia, radioecologiia. 50(2)
The genes of detoxication, MTHFR and p53 were studied in Down' and Ehlers-Danlos syndrome cells. The frequency GSTM1(0/0) genotype in Down syndrome patients was in 1.5 times higher than in control cells (p0.069). Opposite the frequency GSTM1(0/0) gen
Autor:
N S, Kuz'mina, L I, Ushenkova, Zh M, Shagirova, G O, Sheĭkhaev, V F, Mikhaĭlov, L A, Kurbatova, V K, Mazurik, A V, Rubanovich, G D, Zasukhina
Publikováno v:
Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova. 109(4)
Polymorphisms of glutation-S-transferase (GSTM1, GSTT1 GSTP1) and methylentetrahydrofolate reductase (MTHFR) genes have been studied in DNA from blood lymphocytes of 18 patients with Down's syndrome and 61 controls. Frequencies of normal alleles of G
Autor:
V K, Mazurik, V F, Mikhaĭlov, L N, Ushenkova, N M, Nadezhina, N F, Raeva, V Iu, Nugis, A V, Sevan'kaev, I K, Khvostunov, E V, Golub, G F, Mikhaĭlova, D C, Lloyd
Publikováno v:
Radiatsionnaia biologiia, radioecologiia. 46(4)
Molecular-biochemical and cytogenetic analyses were made on blood cells of 17 radiation accident victims who, from 1.7 to 43.8 years previously, had suffered acute radiation sickness (ARS) ranging from severity grades I to IV. Molecular-biochemical d
Publikováno v:
Radiatsionnaia biologiia, radioecologiia. 46(2)
The information significance of the immunological indexes for the prognosis of gravity of course and of outcome of an acute radiation disease for the people after the exposure of ionizing radiation in clinically significant doses is studied. The valu
Publikováno v:
Radiatsionnaia biologiia, radioecologiia. 45(5)
The molecular manifestations of radiation-induced genome instability-changes of the DNA structure, the excision DNA repair and the contents of the reactive oxygen forms in bone marrow cells of the repair proficient mice (CBA) and of the repair-defect
Publikováno v:
Radiatsionnaia biologiia, radioecologiia. 44(5)
To analyse a role of the factor of a genetic fundamentals of cells in formation of radiation-induced genome instability (RIGI) we investigated a condition of DNA pattern, content of superoxide anion-radical O2*- and a sum of reactive oxigen species (
Autor:
V K, Mazurik, V F, Mikhaĭlov
Publikováno v:
Radiatsionnaia biologiia, radioecologiia. 44(3)
The scientific bases, problems, methods and prospects for the development of a new scientific direction "Molecular epidemiology of late consequences of ionizing radiation influence on the man" are reviewed. It is marked, that for two decades on the b
Publikováno v:
Radiatsionnaia biologiia, radioecologiia. 43(6)
The aim of the research is a further analysis of a problem concerning two (regulatory and damaging) functions of reactive oxygen species (ROS) in viability of organism cells under acute exposure to ionizing radiation. For this purpose the ROS content
Publikováno v:
Radiatsionnaia biologiia, radioecologiia. 43(1)
Reactive oxygen species (ROS) have a few possible effects, such as metabolic (participation in regulation of protein functions), damaging (oxidative damage to proteins, lipids and nucleic acids) and signal; the latter is reviewed in the article. Supe
Autor:
V K, Mazurik, B B, Moroz
Publikováno v:
Patologicheskaia fiziologiia i eksperimental'naia terapiia. (1)
The paper analyzes the topical problems of radiobiology in the light of the present-day data on the molecular biology and biochemistry of p53 protein that is an integrator of stress signals from various damaging exposures and that fulfills the functi