Zobrazeno 1 - 10
of 31
pro vyhledávání: '"V K, Gorodetskiĭ"'
Publikováno v:
Biomeditsinskaya Khimiya. 57:133-137
In order to create new oral vanadyl organic complexes-based drugs for the treatment of diabetes mellitus biligand vanadyl derivative of L-malic acid (bis(L-malato)oxovanadium(IV) was prepared and its potential as a novel hypoglycemic agent was studie
Autor:
I R, Kovel'man, A I, Tochilkin, N F, Beliaeva, V K, Gorodetskiĭ, V A, Kniazhev, S B, Tkachenko, L L, Semenov, N V, Semenova
Publikováno v:
Voprosy meditsinskoi khimii. 48(4)
The pharmacological approaches to the treatment of type 2 diabetes mellitus were reviewed. Special attention was paid to the new therapeutic agents that are able to decrease plasma glucose levels. The possible mechanisms of the hypoglycemic effects a
Publikováno v:
Voprosy meditsinskoi khimii. 46(4)
Vanadium compounds as insulin mimics with promising therapeutic properties are reviewed. The biological effects of both inorganic forms of vanadium and vanadyl organic complexes are decried for various animal models. These effects include hypoglycemi
Publikováno v:
Voprosy meditsinskoi khimii. 46(2)
The serum glucose concentration, HbAc1, fructoseamine, the activity of AST, ALT, amylase, glycogen content and glucokinase activity in rat hepatocytes were examined in streptozotocin-diabetic rats during long-term orthovanadate and vanadyl sulphate t
Autor:
B F, Korovkin, N F, Beliaeva, S A, Kraevoĭ, M A, Golubev, V K, Gorodetskiĭ, M S, Markova, O L, Kol'chenko
Publikováno v:
Voprosy meditsinskoi khimii. 45(3)
Variation of fructose 2,6-bisphosphate (F-2,6-P2) content in the peripheral blood lymphocytes of patients with diabetes mellitus (type II) was investigated. The 2.5-fold increase of F-2,6-P2 level compared with to the control group was observed in un
Publikováno v:
Voprosy meditsinskoi khimii. 43(4)
The influence of oral inulin administration on glucose and fructose content in blood, glucose and ketone bodies in urine, and fructose-2,6-diphosphate content in liver was investigated in rats with streptozotocin diabetes. Short-term administration (
Autor:
N F, Beliaeva, M A, Golubev, M S, Markova, O L, Kol'chenko, N N, Lamzina, V K, Gorodetskiĭ, L N, Viktorova, M I, Balabolkin, B F, Korovkin
Publikováno v:
Biulleten' eksperimental'noi biologii i meditsiny. 122(9)
Publikováno v:
Voprosy meditsinskoi khimii. 42(3)
The activity of phosphofructokinase-2, fructose, 1,6-bisphosphatase, glucokinase, and also the level of fructose 2,6-bisphosphate and glycogen were examined in the liver of normal, and streptozotocin-diabetic rats. It was shown that the activity of p
Autor:
B F, Korovkin, N F, Beliaeva, L N, Viktorova, M A, Golubev, V K, Gorodetskiĭ, M S, Markova, A V, Saiapin, N S, Stvolinskaia
Publikováno v:
Vestnik Rossiiskoi akademii meditsinskikh nauk. (2)
The molecular mechanisms of the inhibitory action of fructose- 2,6-bisphosphate (F-2,6-P2) on fructose-1,6-biphosphatase (FB-Pase-1), the key enzyme of gluconeogenesis, and the those of the activating action of F-2,6-P2 on phosphofructo-1-kinase (PFK
Autor:
A V, Dreval', N V, Anykina, D P, Tishin, V G, Vysotskiĭ, T A, Iatsyshina, V K, Gorodetskiĭ, L K, Viktorova
Publikováno v:
Problemy endokrinologii. 40(2)
Using indirect colorimetry, the authors demonstrated disordered energy metabolism at rest in patients with insulin-dependent diabetes mellitus (IDDM) with a moderate decompensation of metabolism: carbohydrate oxidation was reduced and fat and protein