Synthesis, characterisation and Pickering emulsifier performance of poly(stearyl methacrylate)-poly(

Autor: V J, Cunningham, S P, Armes, O M, Musa

Publikováno v: Polymer Chemistry

Block copolymer spheres, worms or vesicles can be prepared via RAFT dispersion polymerisation of N-(methacryloyloxy)ethyl pyrrolidone in n-dodecane using a poly(stearyl methacrylate) chain transfer agent.
A near-monodisperse poly(stearyl methacr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::cc58d71dea1bc2c79f18c28127b57168
https://pubmed.ncbi.nlm.nih.gov/28496522

Discovery of ¹⁸ F Labeled AZD5213 Derivatives as Novel Positron Emission Tomography (PET) Radioligands Targeting Histamine Subtype-3 Receptor.

Autor: Song Z; Department of Radiology and Imaging Sciences, Emory University, 1364 Clifton Road, Atlanta, GA, 30322, USA., Li Y; Department of Radiology and Imaging Sciences, Emory University, 1364 Clifton Road, Atlanta, GA, 30322, USA., Dahl K; PET Science Centre, Precision Medicine and Biosamples, Oncology R&D, AstraZeneca, Karolinska Institutet, Stockholm, Sweden.; Department of Clinical Neuroscience, Centre for Psychiatry Research, Karolinska Institutet and Stockholm County Council, Stockholm, Sweden., Chaudhary A; Department of Radiology and Imaging Sciences, Emory University, 1364 Clifton Road, Atlanta, GA, 30322, USA., Sun Z; Department of Pharmacology and Chemical Biology, Emory University School of Medicine, Atlanta, GA, 30322, USA., Zhou X; Department of Radiology and Imaging Sciences, Emory University, 1364 Clifton Road, Atlanta, GA, 30322, USA., Chen J; Department of Radiology and Imaging Sciences, Emory University, 1364 Clifton Road, Atlanta, GA, 30322, USA., Gao Y; Department of Radiology and Imaging Sciences, Emory University, 1364 Clifton Road, Atlanta, GA, 30322, USA., Rong J; Department of Radiology and Imaging Sciences, Emory University, 1364 Clifton Road, Atlanta, GA, 30322, USA., Zhao C; Department of Radiology and Imaging Sciences, Emory University, 1364 Clifton Road, Atlanta, GA, 30322, USA., Patel JS; Department of Radiology and Imaging Sciences, Emory University, 1364 Clifton Road, Atlanta, GA, 30322, USA.; Department of Radiation Oncology, Winship Cancer Institute of Emory University, Atlanta, GA, 30322, USA., Collier L; Department of Radiology and Imaging Sciences, Emory University, 1364 Clifton Road, Atlanta, GA, 30322, USA., Ran C; Athinoula A. Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, 02114, USA., Zhai C; Department of Radiology and Imaging Sciences, Emory University, 1364 Clifton Road, Atlanta, GA, 30322, USA., Zhang L; Department of Radiology and Imaging Sciences, Emory University, 1364 Clifton Road, Atlanta, GA, 30322, USA., Haider A; Department of Radiology and Imaging Sciences, Emory University, 1364 Clifton Road, Atlanta, GA, 30322, USA., Mühlfenzl KS; Early Chemical Development, Pharmaceutical Sciences, R&D, AstraZeneca Pharmaceuticals, Gothenburg, 43183, Sweden., Yuan H; Department of Pharmacology and Chemical Biology, Emory University School of Medicine, Atlanta, GA, 30322, USA., Elmore CS; Early Chemical Development, Pharmaceutical Sciences, R&D, AstraZeneca Pharmaceuticals, Gothenburg, 43183, Sweden., Schou M; PET Science Centre, Precision Medicine and Biosamples, Oncology R&D, AstraZeneca, Karolinska Institutet, Stockholm, Sweden.; Department of Clinical Neuroscience, Centre for Psychiatry Research, Karolinska Institutet and Stockholm County Council, Stockholm, Sweden., Liang SH; Department of Radiology and Imaging Sciences, Emory University, 1364 Clifton Road, Atlanta, GA, 30322, USA.

Publikováno v: Chembiochem : a European journal of chemical biology [Chembiochem] 2024 Sep 20, pp. e202400655. Date of Electronic Publication: 2024 Sep 20.

Unexpectedly high affinity of a novel histamine H(3) receptor antagonist, GSK239512, in vivo in human brain, determined using PET

Autor: S, Ashworth, A, Berges, E A, Rabiner, A A, Wilson, R A, Comley, R Y K, Lai, R, Boardley, G, Searle, R N, Gunn, M, Laruelle, V J, Cunningham

Publikováno v: British journal of pharmacology. 171(5)

This study aimed to investigate the relationship between the plasma concentration (PK) of the novel histamine H3 receptor antagonist, GSK239512, and the brain occupancy of H(3) receptors (RO) in healthy human volunteers.PET scans were obtained after

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::357181e96ea9e00132b6eca411951678
https://pubmed.ncbi.nlm.nih.gov/24670146

Characterisation of tumour blood flow using a 'tissue-isolated' preparation

Autor: V. J. Cunningham, Gillian M. Tozer, Vivien E. Prise, K. M. Shaffi

Publikováno v: British Journal of Cancer

Tumour blood flow was characterised in a 'tissue-isolated' rat tumour model, in which the vascular supply is derived from a single artery and vein. Tumours were perfused in situ and blood flow was calculated from simultaneous measurement of (1) venou

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1dbf02a52a3c3ba6c52d479c98b9da81
http://europepmc.org/articles/PMC2033701

Detection of telomerase expression in fine-needle aspirations and fluids

Autor: V J, Cunningham, N, Markham, A L, Shroyer, K R, Shroyer

Publikováno v: Diagnostic cytopathology. 18(6)

The cytologic examination of fine-needle aspirates and fluid specimens is plagued by a persistent false negative rate. The rate of false negative results will be decreased if sensitive molecular assays can be developed to detect cytologically maligna

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::218506cb8c2a2dc3220fd30dcf0654b7
https://pubmed.ncbi.nlm.nih.gov/9626516