Zobrazeno 1 - 10
of 47
pro vyhledávání: '"V J, Bubb"'
Autor:
Lauren J. McIver, David A. Boothman, L-S Li, V. J. Bubb, J. F. McCormick, C. L. Galindo, Angela C. George, Harold R. Garner, J. P. Quinn
Publikováno v:
Cancer Research. 70:P2-06
Background: There is a strong genetic component to breast cancer, which is the most common neoplasm in women; however current risk markers are few, accounting for less than 10% of breast cancer cases. This means that the majority of familial breast c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4264daa57a6839e9aaa5cd1cc5149fc7
https://doi.org/10.1158/0008-5472.sabcs10-p2-06-03
https://doi.org/10.1158/0008-5472.sabcs10-p2-06-03
Publikováno v:
Current topics in behavioral neurosciences. 12
The serotonin transporter is a key regulator of the bioavailability of serotonin and therefore any modulation in the expression or action of the transporter would be expected to have consequences on behaviour. The transporter has therefore become a t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::beb8f028ee87f09b0d93862991d10e1d
https://pubmed.ncbi.nlm.nih.gov/22261701
https://pubmed.ncbi.nlm.nih.gov/22261701
Autor:
J. F. McCormick, Michael A. Skinner, Angela C. George, V. J. Bubb, Long Shan Li, J. P. Quinn, D. H. Abid Alkadem, David A. Boothman, Lauren J. McIver, Harold R. Garner, Cristi L. Galindo
We sequenced the 5′ UTR of the estrogen-related receptor gamma gene (ERR-γ) in ~500 patient and volunteer samples and found that longer alleles of the (AAAG) n microsatellite were statistically and significantly more likely to exist in the germlin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0bd56835ffdc7ab25b7acd9e61382c8
https://europepmc.org/articles/PMC3374865/
https://europepmc.org/articles/PMC3374865/
Publikováno v:
Histology and histopathology. 23(3)
Activity-dependent neuroprotective protein (ADNP) is a VIP-regulated gene, which is essential for brain development. A synthetic peptide (NAP) derived from the ADNP sequence is highly neuroprotective, therefore it has been hypothesised that ADNP has
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8c0a9328036bc32839460f05e0f29654
https://pubmed.ncbi.nlm.nih.gov/18072088
https://pubmed.ncbi.nlm.nih.gov/18072088
Publikováno v:
The European journal of neuroscience. 17(2)
We have demonstrated that a variable number tandem repeat domain (VNTR) within intron 2 of the serotonin transporter gene is a transcriptional regulatory domain which is potentially correlated with a predisposition to affective disorders and other be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b3f77e69f2371e0f4828e3648124b1bc
https://pubmed.ncbi.nlm.nih.gov/12542679
https://pubmed.ncbi.nlm.nih.gov/12542679
Publikováno v:
Histopathology. 39(6)
Members of the cadherin and catenin families are involved in chondrogenesis and catenin gene mutations have been detected in malignant tumours of bone. This study was undertaken to assess in detail expression of cadherin, beta-catenin and the associa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2de4b4b2f2ac9ec787c6dfdc5c999cfe
https://pubmed.ncbi.nlm.nih.gov/11903580
https://pubmed.ncbi.nlm.nih.gov/11903580
Autor:
A H, Wyllie, C O, Bellamy, V J, Bubb, A R, Clarke, S, Corbet, L, Curtis, D J, Harrison, M L, Hooper, N, Toft, S, Webb, C C, Bird
Publikováno v:
British journal of cancer. 80
Apoptosis has long been known to be effected through a common sequence of structural changes, despite the wide variety of initiating stimuli. These common structural events appear to depend upon activation of a set of enzymes (caspases) which direct
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::290f063c7f3472aa4957957870f882cf
https://pubmed.ncbi.nlm.nih.gov/10466759
https://pubmed.ncbi.nlm.nih.gov/10466759
Autor:
C A, Midgley, S, White, R, Howitt, V, Save, M G, Dunlop, P A, Hall, D P, Lane, A H, Wyllie, V J, Bubb
Publikováno v:
The Journal of pathology. 181(4)
The tumour suppressor gene APC codes for a 2843-amino acid protein whose precise functions are still poorly understood. This paper describes the development of two new antisera to APC (to amino- and carboxy-terminal epitopes) which permit localizatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4c9eaada81632b3cb8de6380c0127260
https://pubmed.ncbi.nlm.nih.gov/9196441
https://pubmed.ncbi.nlm.nih.gov/9196441
Publikováno v:
The Journal of pathology. 181(4)
Codon 12 of the K-ras oncogene was screened for mutations in 65 surgically-resected primary pulmonary adenocarcinomas and in 32 tissue foci of alveolar atypical hyperplasia (AAH) by a polymerase chain reaction (PCR)-based method. Mutations in either
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::be24c1d6c662c47e49ac75e2e24404eb
https://pubmed.ncbi.nlm.nih.gov/9196437
https://pubmed.ncbi.nlm.nih.gov/9196437
Autor:
C A, Cooper, V J, Bubb, N, Smithson, R L, Carter, S, Gledhill, D, Lamb, A H, Wyllie, F A, Carey
Publikováno v:
The Journal of pathology. 180(1)
Four genetic polymorphisms in the APC and MCC genes at chromosome 5q21 were analysed for loss of heterozygosity (LOH) in 97 primary squamous carcinomas and adenocarcinomas of the lung. LOH was identified in at least two polymorphic loci in 41 percent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3c79a188fc82a195459cccbca50dc235
https://pubmed.ncbi.nlm.nih.gov/8943812
https://pubmed.ncbi.nlm.nih.gov/8943812