Zobrazeno 1 - 5
of 5
pro vyhledávání: '"V J, Assikis"'
Autor:
R M, O'Regan, A, Cisneros, G M, England, J I, MacGregor, H D, Muenzner, V J, Assikis, M M, Bilimoria, M, Piette, Y P, Dragan, H C, Pitot, R, Chatterton, V C, Jordan
Publikováno v:
JNCI Journal of the National Cancer Institute. 90:1552-1558
Background Tamoxifen has been shown to promote the growth of human endometrial tumors implanted in athymic mice, and it has been associated with a twofold to threefold increase in endometrial cancer. Toremifene, a chlorinated derivative of tamoxifen,
Autor:
V J, Assikis, V C, Jordan
Publikováno v:
Oncology (Williston Park, N.Y.). 11(2 Suppl 1)
Tamoxifen is the most widely prescribed endocrine therapy for breast cancer, with more than 7.5 million woman-years of clinical experience. Tamoxifen has both antiestrogenic and estrogenic activity. The antiestrogenic activity accounts for its effica
Publikováno v:
The cancer journal from Scientific American. 2(3)
Toxifen, a nonsteroidal antiestrogen, is currently the most widely used adjuvant therapy for the treatment of breast cancer. Though the efficacy of tamoxifen has been well documented in clinical trials, the certainty over the duration of therapy is l
Autor:
V J, Assikis, V C, Jordan
Publikováno v:
Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer. 140
Autor:
V C, Jordan, V J, Assikis
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 1(5)
During the past 5 years, a number of case reports and clinical trial results have associated tamoxifen therapy with an increased incidence of endometrial carcinoma. A review of the literature shows that there are over 200 cases of endometrial carcino