Zobrazeno 1 - 10
of 13
pro vyhledávání: '"V Iu, Makeev"'
Publikováno v:
Biofizika. 60(1)
Conservative regions varying in length from 30 to 70 nucleotides (nt) are revealed as a result of interspecies comparison of homologous nucleotide sequences of the loci, genes controlling early development in Drosophila species. These regions are obs
Publikováno v:
Biofizika. 58(6)
The correlation was observed between DNA segments characterized by periodic patterns of nucleotides and nucleosome DNA binding sites predicted by the profiles of local DNA flexibility. Exons of human type I and VII collagen genes loci have been chose
Publikováno v:
Biofizika. 57(2)
Here we analyzed an option to predict the structure of cis-regulatory modules that consist of binding sites of different proteins (heterogeneous cis-regulatory modules) using mutual positional correlations between protein-DNA binding experimental dat
Publikováno v:
Biofizika. 56(6)
We developed an approach for effective estimating the correlations in the noise component of gene expression data. An efficent noise reduction technique has been suggested. The resulting technique has been applied to E. coli microarray data and teste
Publikováno v:
Biofizika. 56(1)
Transcriptional regulation of gene expression in higher eukaryotes is driven by sophisticated protein complexes of transcription factors. On the DNA level, there are composite elements containing sites of different DNA-binding proteins. We use the hy
Publikováno v:
Biofizika. 55(6)
Nucleotide DNA sequences within the clusters of transcription starts, determined by the method of cap analysis of gene expression, have some distinguishing features. The sequences of these clusters are rich in nucleotides C and G, and there is an asy
Autor:
I V, Kulakovskiĭ, V Iu, Makeev
Publikováno v:
Biofizika. 54(6)
For 39 proteins regulating the transcription of Drosophila melanogaster, refined motifs typical for nucleotide sequences specifically interacting with these proteins have been constructed using the new logarithm ChiPMunk. The entire spectrum of avail
Publikováno v:
Biofizika. 53(3)
Regions with a quasiperiodical location of exon--intron sites have been found in the loci of genes of I and VII type collagens (with a total length of exons more than 15% of the entire size of the locus). The periods observed are similar to periods t
Autor:
S V, Rakhmanov, V Iu, Makeev
Publikováno v:
Biofizika. 53(3)
Some effects hindering the construction of knowledge-based potentials of atom-atom interactions in problems of biopolymer modeling have been considered. It was shown that some limitations are overcome by considering the distribution of distances betw
Publikováno v:
Biofizika. 51(4)
Micro- and minisatellites constitute an essential part of DNA with a low sequence complexity and carry several important functions. A search for tandem repeats in the human genome with a length of a repeat unit of up to 70 bp, including repeats with