Zobrazeno 1 - 10
of 164
pro vyhledávání: '"V I Kapel'ko"'
Publikováno v:
Bulletin of Experimental Biology and Medicine. 143:408-410
Long-term administration of beta-hydroxy-beta-methylglutaryl coenzyme A reductase inhibitor atorvastatin to rats was accompanied by an increase in the relative weight of the heart and decrease in the rate of pressure development in the isovolumic hea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f0a0ef401c9a3babfdeadc0caabb334
https://doi.org/10.1007/s10517-007-0142-7
https://doi.org/10.1007/s10517-007-0142-7
Autor:
V L, Lakomkin, V I, Kapel'ko
Publikováno v:
Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova. 98(2)
The oxidative stress in cardiomyocytes is a component of cardiotoxic action of adriamycin. To distinguish the importance of this component we have compared initial effects of hydrogen peroxide and adriamycin on the contractile function and a tone of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a51240603957cd148857782efd133d31
https://pubmed.ncbi.nlm.nih.gov/22650069
https://pubmed.ncbi.nlm.nih.gov/22650069
Autor:
E I, Chazov, O V, Rodnenkov, A V, Zorin, V L, Lakomkin, V V, Gramovich, O N, Vyborov, A G, Dragnev, A A, Timoshin, L I, Buriachkovskaia, A A, Abramov, A B, Dobrovol'skiĭ, G V, Maksimov, V P, Masenko, E V, Arzamastsev, V I, Kapel'ko, A F, Vanin
Publikováno v:
Kardiologiia. 51(11)
On the basis of earlier executed studies of hypotensive effect of dinitrosyl iron complexes (DNIC) with glutathione, the drug has been created in industrial conditions named oxacom. Preliminary pharmacological studies of oxacom have not revealed nega
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ed926fd7cfa30431190f0e603a9812f7
https://pubmed.ncbi.nlm.nih.gov/22117768
https://pubmed.ncbi.nlm.nih.gov/22117768
Autor:
V I, Kapel'ko
Publikováno v:
Kardiologiia. 51(1)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b9573a226d92036bead12eb8987bf3f6
https://pubmed.ncbi.nlm.nih.gov/21626807
https://pubmed.ncbi.nlm.nih.gov/21626807
Publikováno v:
Kardiologiia. 50(12)
Functional, biochemical and morphological studies of rat cardiac muscle after single injection of adriamycin (2.2 mg/kg) were carried out. The myocardium was taken for studies in 2 hours and in 2-3 weeks after adriamycin injection. The isolated heart
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c7a32274dc55af723ac8898a35c3e4f9
https://pubmed.ncbi.nlm.nih.gov/21591392
https://pubmed.ncbi.nlm.nih.gov/21591392
Autor:
V L, Lakomkin, V I, Kapel'ko
Publikováno v:
Kardiologiia. 49(10)
Mitochondria are believed to be both main origin and target of oxidative stress in cells. In the present study we used novel mitochondria-targeted antioxidant SkQ1 using triphenylphosphonium cation as a driver. The substance was alimentary given to r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::536477025955054ab8e732f43045c326
https://pubmed.ncbi.nlm.nih.gov/19845521
https://pubmed.ncbi.nlm.nih.gov/19845521
Autor:
A V, Marchenko, M V, Sidorova, A V, Sekridova, V N, Bushuev, V L, Lakomkin, Ts R, Orlova, O V, Stepanova, V I, Kapel'ko, D M, Watterson, L J, Van Eldik, Zh D, Bespalova, V P, Shirinskiĭ
Publikováno v:
Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova. 95(5)
Nonapeptide H-Arg-Lys-Lys-Tyr-Lys-Tyr-Arg-Arg-Lys-NH2 corresponding to a modified sequence of autoinhibitory region of myosin light chain kinase (MLCK) was synthesized from L-amino acids and from D-amino acids. Using nuclear magnetic resonance spectr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::62f66ef98cf6b470c03b8f2c39d680a3
https://pubmed.ncbi.nlm.nih.gov/19569527
https://pubmed.ncbi.nlm.nih.gov/19569527
Autor:
V I, Kapel'ko, Zh D, Bespalova, E E, Efremov, V L, Lakomkin, Ts R, Orlova, S V, Lakomkin, M V, Sidorova, A A, Az'muko, A S, Molokoedov, T V, Sharf
Publikováno v:
Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova. 95(5)
Neuropeptide FF (H-Phe-Leu-Phe-Gln-Pro-Gln-Arg-Phe-NH2) injected intravenously temporarily enhanced the arterial pressure (AP) and the heart rate (HR). However, its role in the regulation of blood circulation is obscure. To study the properties of th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9b15307c8b6fb6ec2f1f20a18b921556
https://pubmed.ncbi.nlm.nih.gov/19569525
https://pubmed.ncbi.nlm.nih.gov/19569525
Autor:
V L, Lakomkin, A A, Timoshin, Ts R, Orlova, S A, Gubkina, A N, Storozhilova, T E, Gvozdik, A B, Dobrovol'skiĭ, E K, Ruuge, A F, Vanin, V I, Kapel'ko, B A, Lapin, E I, Chazov
Publikováno v:
Kardiologiia. 49(5)
We studied action of a nitric oxide donor, dinitrosyl complex of iron (DNIC) with glutathione as a ligand on the hemodynamics of normotensive Wistar rats, spontaneously hypertensive rats (SHR), and monkeys. Intravenous DNIC introduction (2-120 mg/kg)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::244c0264797c85660aca5bff984a1fbc
https://pubmed.ncbi.nlm.nih.gov/19463136
https://pubmed.ncbi.nlm.nih.gov/19463136
Publikováno v:
Basic Research in Cardiology. 85:307-314
Isolated perfused guinea pig hearts were arrested by a high K+ cardioplegic solution containing (PG group) or lacking (control group) 10 mM phosphocreatine + 15 mM glutamate. Total normothermic ischemia lasted 45 min followed by 30 min reperfusion. M
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df6f752031d46f24dbfd34c17b82cc77
https://doi.org/10.1007/bf01907119
https://doi.org/10.1007/bf01907119