Zobrazeno 1 - 4
of 4
pro vyhledávání: '"V I, Poseva"'
Autor:
Molodavkin Gm, V. P. Lezina, V. I. Poseva, G. V. Mokrov, T. A. Voronina, A. M. Likhosherstov, T. A. Gudasheva
Publikováno v:
Pharmaceutical Chemistry Journal. 47:464-469
A series of new 1,2,4,5-tetrahydro-3H-pyrrolo[1,2-a][1,4]diazepin-3-one derivatives were synthesized from widely available furfurol, 3-aminopropionic acid, and amines. The antidepressant and anxiolytic properties of the obtained compounds were invest
Antidepressant Effect of Dimeric Dipeptide GSB-106, an Original Low-Molecular-Weight Mimetic of BDNF
Autor:
T. A. Voronina, T. A. Gudasheva, Sergey B. Seredenin, Molodavkin Gm, S. A. Litvinova, V. I. Poseva, E A Elizarova, T. L. Garibova
Publikováno v:
Acta Naturae
A large amount of clinical and experimental data suggest the involvement of neurotrophins, in particular the brain-derived neurotrophic factor (BDNF), in depression pathogenesis. However, the therapeutic use of BDNF is limited because of its instabil
Autor:
O. I. Epshtein, Molodavkin Gm, V. I. Poseva, M. A. Putilovskii, V. V. Andreeva, I. A. Ertuzun, Yu. L. Dugina, N. I. Suslov, N. N. Yakovleva, T. A. Voronina
Publikováno v:
Bulletin of experimental biology and medicine. 159(6)
The anxiolytic and antidepressant activities of complex preparations divaza and brizantin containing antibodies to brain-specific protein S100 were estimated using Vogel conflict test and Nomura forced swimming test. Course treatment (5 days) of briz
Autor:
V S, Kudrin, P M, Klodt, V B, Narkevich, V A, Shipilov, V I, Poseva, G M, Molodavkin, T A, Voronina
Publikováno v:
Eksperimental'naia i klinicheskaia farmakologiia. 75(10)
The behavioral and neurochemical effects of synthetic dipeptide fragment GSB-106 of BDNF, administered in a single dose of 0.1 mg/kg (i.p.), have been studied in comparison to amitriptyline (10 mg/kg, i.p.) on the Nomura depressive state model employ