Molecular mechanisms of poliovirus variation and evolution

Autor: V I, Agol

Publikováno v: Current topics in microbiology and immunology. 299

Replication of poliovirus RNA is accomplished by the error-prone viral RNA-dependent RNA polymerase and hence is accompanied by numerous mutations. In addition, genetic errors may be introduced by nonreplicative mechanisms. Resulting variability is m

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::dda1e4bdcddb7d59880f40509e16ed04
https://pubmed.ncbi.nlm.nih.gov/16568901

[Variable mechanisms of RNA-recombination]

Autor: A P, Gmyl', V I, Agol

Publikováno v: Molekuliarnaia biologiia. 39(4)

Recombination is widespread among RNA viruses but underlying mechanisms remain poorly understood. Until recently, replicative template switching was considered the only possible mechanism of RNA recombination but new evidence suggests that other vari

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::df238910acf908e76408f0611a7a062a
https://pubmed.ncbi.nlm.nih.gov/16083010

[Genomic instability in picornaviruses]

Autor: V I, Agol

Publikováno v: Molekuliarnaia biologiia. 36(2)

Picornaviruses are small animal RNA viruses and include wtiological agents of poliomyelitis, foot and mouse disease, hepatitis A, etc. Replication of their genome results in many mutations, which are close in number to a viability threshold. Hence ev

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::d9d80640dc9de97506ac47d71c44bcce
https://pubmed.ncbi.nlm.nih.gov/11969090

New Ways of Initiating Translation in Eukaryotes?

Autor: M. Holcik, M Jr Gale, S. A. Chappell, J. Hershey, B. He, N. Standart, Robert J. Schneider, N. Nakashima, Jing Chen, J. Pelletier, T. Rouault, D. R. Morris, O. Donzé, J. B. Harford, L. E. Maquat, A. A.M. Thomas, F. Bayard, T. Skern, S. Miyamoto, T. Hohn, A. Siddiqui, Ian Mohr, S. M. Tahara, D. R. Cavener, L. S. Jefferson, R. Andino, Y. Groner, S. Lemon, S. R. Kimball, E. G. Moss, E. Goldman, W. Sossin, B. Joshi, A. Dasgupta, B. J. Lamphear, K. Igarashi, G. Sullivan Read, V. P. Mauro, R. J. Kaufman, Daniel R. Schoenberg, N. Sonenberg, M. Hatzoglou, J. D. Richter, Leslie A. Schiff, R. E. Lloyd, R. M. Krug, P. Hershey, G. Witherell, C. U.T. Hellen, G. C. Scheper, A. C. Prats, V. I. Agol, W. Filipowicz, A. Palmenberg, R. E. Rhoads, M. Kiledjian, J. L.E. Darlix, L. Gehrke, V. Racaniello, P. J. Farabaugh, R. Rivera-Pomar, M. W. Hentze, M. Wormington, O. Elroy-Stein, M. B. Mathews, M. G. Katze, B. L. Semler, T. Pe'ery, N. T. Parkin, A. Sachs, A. Kimchi, Raymond Kaempfer, S. Peltz, R. Jagus, E. V. Pilipenko, C. P. Hunter, K. Kirkegaard, M. Kozak, R. Duncan, A. E. Koromilas, R. Jackson, Encarnación Martínez-Salas, E. Wimmer, T. V. Pestova, V. Kruys, J. Wilusz, P. Sarnow, J. J. Toulmé

Three interesting ideas about the initiation of translation in eukaryotes have recently emerged in the literature. One is the possibility that internal initiation of translation might occur not only with viral but also with some cellular mRNAs. The s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3ece8c041f3a06cd631e6d435c8bd8c
https://europepmc.org/articles/PMC86772/

Final checkpoint in the drug-promoted and poliovirus-promoted apoptosis is under post-translational control by growth factors

Autor: E A, Tolskaya, L I, Romanova, M S, Kolesnikova, T A, Ivannikova, V I, Agol

Publikováno v: Journal of cellular biochemistry. 63(4)

The treatment of HeLa subline (HeLa-B) cells with cycloheximide or Actinomycin D resulted in a rapid (approximately 1.5 h and approximately 2.5 h, respectively) development of morphological and biochemical signs of apoptosis. The addition of fetal bo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::0eb894d101c3c99b14a0b36db2705783
https://pubmed.ncbi.nlm.nih.gov/8978458