Zobrazeno 1 - 10
of 599
pro vyhledávání: '"V Hampson"'
Autor:
Astaria, Tri1 (AUTHOR) triastari55@gmail.com, Purnomo, Yoppy Wahyu1 (AUTHOR), Firdaus, Fery Muhamad1 (AUTHOR)
Publikováno v:
Technometrics. Feb2024, Vol. 66 Issue 1, p133-134. 2p.
Autor:
Yanni Hao, Wei-Chun Hsu, Craig S Parzynski, Evgeny Degtyarev, Lisa V Hampson, Aisha Masood, Wen-Hsing Wu
Publikováno v:
Journal of Comparative Effectiveness Research, Vol 12, Iss 7 (2023)
Aim: To contextualize the effectiveness of tisagenlecleucel versus real-world standard of care (SoC) in relapsed/refractory follicular lymphoma. Materials & methods: A retrospective indirect matched comparison study using data from the phase II ELA
Externí odkaz:
https://doaj.org/article/2e68b7b1092c4873bb523cd37838a9af
Publikováno v:
BMC Medical Research Methodology, Vol 19, Iss 1, Pp 1-17 (2019)
Abstract Background Performing well-powered randomised controlled trials (RCTs) of new treatments for rare diseases is often infeasible. However, with the increasing availability of historical data, incorporating existing information into trials with
Externí odkaz:
https://doaj.org/article/56c7c84340f8470582cb5e739d00ed1d
Autor:
Jonathan A. Cook, Steven A. Julious, William Sones, Lisa V. Hampson, Catherine Hewitt, Jesse A. Berlin, Deborah Ashby, Richard Emsley, Dean A. Fergusson, Stephen J. Walters, Edward C. F. Wilson, Graeme Maclennan, Nigel Stallard, Joanne C. Rothwell, Martin Bland, Louise Brown, Craig R. Ramsay, Andrew Cook, David Armstrong, Doug Altman, Luke D. Vale
Publikováno v:
Trials, Vol 19, Iss 1, Pp 1-8 (2018)
Abstract Background A key step in the design of a RCT is the estimation of the number of participants needed in the study. The most common approach is to specify a target difference between the treatments for the primary outcome and then calculate th
Externí odkaz:
https://doaj.org/article/93ca295eced54b009edc65547cf7cb8e
Autor:
William Sones, Steven A. Julious, Joanne C. Rothwell, Craig Robert Ramsay, Lisa V. Hampson, Richard Emsley, Stephen J. Walters, Catherine Hewitt, Martin Bland, Dean A. Fergusson, Jesse A. Berlin, Doug Altman, Luke David Vale, Jonathan Alistair Cook
Publikováno v:
Trials, Vol 19, Iss 1, Pp 1-11 (2018)
Abstract Background A key step in the design of a randomised controlled trial is the estimation of the number of participants needed. The most common approach is to specify a target difference in the primary outcome between the randomised groups and
Externí odkaz:
https://doaj.org/article/786357260d4a4d0fb61b7c490178b14b
Autor:
Philip Pallmann, Alun W. Bedding, Babak Choodari-Oskooei, Munyaradzi Dimairo, Laura Flight, Lisa V. Hampson, Jane Holmes, Adrian P. Mander, Lang’o Odondi, Matthew R. Sydes, Sofía S. Villar, James M. S. Wason, Christopher J. Weir, Graham M. Wheeler, Christina Yap, Thomas Jaki
Publikováno v:
BMC Medicine, Vol 16, Iss 1, Pp 1-15 (2018)
Abstract Adaptive designs can make clinical trials more flexible by utilising results accumulating in the trial to modify the trial’s course in accordance with pre-specified rules. Trials with an adaptive design are often more efficient, informativ
Externí odkaz:
https://doaj.org/article/efc892793b0644d397320bd46ec68965
Autor:
Jonathan A. Cook, Steven A. Julious, William Sones, Joanne C. Rothwell, Craig R. Ramsay, Lisa V. Hampson, Richard Emsley, Stephen J. Walters, Catherine Hewitt, Martin Bland, Dean A. Fergusson, Jesse A. Berlin, Doug Altman, Luke D. Vale
Publikováno v:
Trials, Vol 18, Iss 1, Pp 1-7 (2017)
Abstract Background A key step in the design of a randomised controlled trial (RCT) is the estimation of the number of participants needed. By far the most common approach is to specify a target difference and then estimate the corresponding sample s
Externí odkaz:
https://doaj.org/article/194e122a087d464fa438367cb1911b4b
Autor:
Jonathan A Cook, Steven A Julious, William Sones, Lisa V Hampson, Catherine Hewitt, Jesse A Berlin, Deborah Ashby, Richard Emsley, Dean A Fergusson, Stephen J Walters, Edward CF Wilson, Graeme MacLennan, Nigel Stallard, Joanne C Rothwell, Martin Bland, Louise Brown, Craig R Ramsay, Andrew Cook, David Armstrong, Douglas Altman, Luke D Vale
Publikováno v:
Health Technology Assessment, Vol 23, Iss 60 (2019)
Background: The randomised controlled trial is widely considered to be the gold standard study for comparing the effectiveness of health interventions. Central to its design is a calculation of the number of participants needed (the sample size) for
Externí odkaz:
https://doaj.org/article/cba0e59595b74186aa0898150edfed89
Autor:
A V Ramanan, L V Hampson, H Lythgoe, A P Jones, B Hardwick, H Hind, B Jacobs, D Vasileiou, I Wadsworth, N Ambrose, J Davidson, P J Ferguson, T Herlin, A Kavirayani, O G Killeen, S Compeyrot-Lacassagne, R M Laxer, M Roderick, J F Swart, C M Hedrich, M W Beresford
Publikováno v:
PLoS ONE, Vol 14, Iss 6, p e0215739 (2019)
IntroductionChronic nonbacterial osteomyelitis (CNO) is a rare autoinflammatory bone disorder primarily affecting children and adolescents. It can lead to chronic pain, bony deformities and fractures. The pathophysiology of CNO is incompletely unders
Externí odkaz:
https://doaj.org/article/9874f4e367b04962a6d22b2eba990e3a
Autor:
Björn Holzhauer, Lisa V. Hampson, John Paul Gosling, Björn Bornkamp, Joseph Kahn, Markus R. Lange, Wen‐Lin Luo, Caterina Brindicci, David Lawrence, Steffen Ballerstedt, Anthony O'Hagan
Publikováno v:
Pharmaceutical Statistics, 2022, Vol.21(5), pp.1005-1021 [Peer Reviewed Journal]
Pharmaceutical companies regularly need to make decisions about drug development programs based on the limited knowledge from early stage clinical trials. In this situation, eliciting the judgements of experts is an attractive approach for synthesisi