Zobrazeno 1 - 10
of 83
pro vyhledávání: '"V H Perry"'
Tectal ablation in neonatal rats leads to retrograde degeneration of retinal ganglion cells whereas similar damage in adults does not. We show here that the behavioral effects are comparably different. When rats with neonatal tectal ablation are test
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d8f72a3879c9986e7e173f1ec08daf1
https://doi.org/10.1007/bf00239583
https://doi.org/10.1007/bf00239583
Autor:
V. H. Perry, Alan Cowey
The ganglion cell layer of the retina was examined for retrograde transneuronal degeneration after removing the striate cortex unilaterally in infant or adult rats. No significant degeneration occurred, even after a survival time of 15 months, and th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e634c97e4989e391596488d637caf59a
https://ora.ox.ac.uk/objects/uuid:e04b11cd-110a-479f-9fdb-82b4cbba81d6
https://ora.ox.ac.uk/objects/uuid:e04b11cd-110a-479f-9fdb-82b4cbba81d6
Autor:
G. Ghoneim, Guilherme Aris Parsekian, V. H. Perry, A. Boucher, Nigel G. Shrive, J. Kroman, T G Brown, P. J. Seibert
Publikováno v:
Proceedings of the Institution of Civil Engineers - Bridge Engineering. 162:157-166
The design, testing and construction of a 33·6 m pre-stressed drop-in girder made with Ductal ultra-high performance fibre-reinforced concrete is presented. This girder was part of a pedestrian bridge that required the largest known volume of this m
Publikováno v:
Canadian Journal of Civil Engineering. 32:1152-1165
Two series of nine architectural shell structures — constructed of a 20 mm thick layer of a new ultra-high performance cement (UPHC) composite with organic fibres (Ductal®) — were proposed to form the roofs of a new station for the light rail tr
Autor:
Thelma Biggs, C. H. Barton, Holly Bowen, V. H. Perry, Derek A. Mann, S. T. Baker, E.S. Phillips
Publikováno v:
Biochemical Society Transactions. 30:774-777
The Nrampl (natural resistance-associated macrophage protein 1) gene modulates the growth of intracellular pathogens and encodes a divalent cation transporter within lysosomes/late endosomes of macrophages. Nrampl modulates the cytoplasmic iron pool.
Publikováno v:
European Journal of Neuroscience. 11:3648-3658
Lesion-induced inflammatory responses in both brain and spinal cord have recently become a topic of active investigation. Using C57BL/6J mice, we compared the tissue reaction in these two central nervous system (CNS) compartments with mechanical lesi
Autor:
Frances M. Platt, T D Butters, Mylvaganam Jeyakumar, Richard L. Proia, V H Perry, Raymond A. Dwek, Mario Cortina-Borja, V Hunnam
Publikováno v:
Proceedings of the National Academy of Sciences. 96:6388-6393
Sandhoff disease is a neurodegenerative disorder resulting from the autosomal recessive inheritance of mutations in the HEXB gene, which encodes the β-subunit of β-hexosaminidase. G M2 ganglioside fails to be degraded and accumulates within lysosom
Publikováno v:
Gene Therapy. 6:471-481
E1-deleted adenoviral vectors expressing the bacterial beta-galactosidase gene were inoculated into the brain of unprimed and primed C3H.He or C57BL/6J mice housed under either conventional or specific-pathogen-free (SPF) conditions. The kinetics of
Autor:
S Betmouni, V H Perry
Publikováno v:
Neuropathology and Applied Neurobiology. 25:19-27
The neuropathological hallmarks of end-stage prion disease are vacuolation, neuronal loss, astrocytosis and deposition of PrPSc amyloid. We have also shown that there is an inflammatory response in the brains of scrapie-affected mice from 8 weeks pos
Publikováno v:
Teratology. 58:174-182
Arylamine N-acetyltransferases (NATs) are important in susceptibility to xenobiotic-induced disorders (e.g., drug-induced autoimmune disease, bladder cancer), but their role in endogenous metabolism is yet to be elucidated. The discovery that human N