Zobrazeno 1 - 5
of 5
pro vyhledávání: '"V G Hale"'
Autor:
C B, Nguyen, L, Harris, E, Szönyi, S A, Baughman, V G, Hale, N O, Dybdal, M D, Sadick, E, Escandón
Publikováno v:
Drug metabolism and disposition: the biological fate of chemicals. 28(5)
In this study, we have characterized the metabolism, tissue disposition, excretion routes, and plasma pharmacokinetics of recombinant human nerve growth factor after single and multiple s.c. administration in male cynomolgus monkeys. Unlabeled nerve
Autor:
Dimitrios T. Boumpas, J Rairie, John C. Davis, D Sinicropi, Susan Manzi, D Averthelyi, James E. Balow, V G Hale, Iain B. McInnes, Cheryl Yarboro, Howard A. Austin, John H. Klippel
Publikováno v:
Lupus. 8(1)
Systemic lupus erythematosus (SLE) is characterized by the production of pathogenic autoantibodies to nucleoprotein antigens, including double-stranded DNA (dsDNA). The deposition of IgG dsDNA immune complexes in glomeruli is thought to be crucial fo
Publikováno v:
Inflammation research : official journal of the European Histamine Research Society ... [et al.]. 45(11)
Objective and Design: Relevance of the preclinical pharmacodynamic, toxicity and pharmacokinetic parameters predicting the clinical potency of nonsteroidal antiinflammatory drugs (NSAIDs) was evaluated. Material: Data for oral potencies of 24 NSAIDs
Autor:
V G, Hale, E D, Bashaw
Publikováno v:
Clinical pharmacy. 12(4)
Autor:
V G, Hale, L Z, Benet
Publikováno v:
Drug metabolism and disposition: the biological fate of chemicals. 19(1)
The rabbit and human both display nonlinear pharmacokinetics of prednisone (PO) and prednisolone (POH). The in vivo apparent clearances of these compounds increase with dose. To determine whether one source of the kinetic nonlinearity is due to hepat