Zobrazeno 1 - 10
of 64
pro vyhledávání: '"V G, Skvortsov"'
Publikováno v:
Pharmaceutical Chemistry Journal. 51:331-336
Pharmacokinetic studies of the new bone-seeking radiopharmaceutical (RP) 68Ga-labeled N,N,N′,N′-ethylenediaminetetrakis(methylenephosphonic acid) (EDTMP) for PET diagnosis of bone metastases showed that 68Ga-EDTMP accumulated rapidly in bone 1 h
Publikováno v:
Pharmaceutical Chemistry Journal. 49:287-291
Pharmacokinetic studies of technetium-99m-labeled N,N,N′,N′-ethylenediaminetetra-kis-(methylenephosphonic acid) (99mTc-EDTMP) showed that this radiopharmaceutical (RP) has high in vivo stability. Studies of the biodistribution of 99mTc-EDTMP were
Publikováno v:
Pharmaceutical Chemistry Journal. 48:357-362
The pharmacokinetic properties of a bone-seeking radiopharmaceutical based on pentaphosphonic acid labeled with technetium-99m (99mTc-PPA) were investigated. The experiments were performed in healthy rats and in rats with a femoral bone-fracture (BF)
Publikováno v:
Pharmaceutical Chemistry Journal. 47:573-576
Studies of the pharmacokinetics of 188Re-human serum albumin microspheres (MSA) of diameter 10 – 20 μm in intact mice showed that the maximum accumulation of activity (about 70%) 5 min at after intravenous administration was in the lungs. Eliminat
Publikováno v:
Pharmaceutical Chemistry Journal. 47:409-414
The pharmacokinetics of 225Ac-labeled hydroxyethylenediphosphoric acid monopotassium salt (225Ac-KHEDP) and 225AcCl3 were studied in intact mice after intravenous administration. The results obtained here showed that in contrast to free 225Ac, 225Ac-
Autor:
V. G. Skvortsov, L. D. Artamonova, G. M. Khomushku, A. S. Shilina, N. B. Épshtein, Yu. Ya. Kharitonov
Publikováno v:
Pharmaceutical Chemistry Journal. 47:446-450
Publikováno v:
Pharmaceutical Chemistry Journal. 47:251-256
The influence of modeled femur callosity on the biodistribution of 188Re-labeled pentaphosphonic acid (188Re-PPA) in rats was studied. The radiopharmaceutical was injected into a tail vein 14 d after fracture. It was established that the presence of
Autor:
O. A. Smoryzanova, A. A. Bryukhanova, V. G. Skvortsov, V. M. Petriev, O. E. Shvert, V. K. Shiryaeva
Publikováno v:
Pharmaceutical Chemistry Journal. 46:443-448
The in vivo biodistributions of the monopotassium salt of hydroxyethylidenediphosphonate labeled with 188Re (188Re-KHEDP) were studied in rats for drug batches prepared with and without Re carrier. Also, the pharmacokinetics of two batches of 188Re-K
Publikováno v:
Pharmaceutical Chemistry Journal. 45:333-340
Investigation of pharmacokinetic characteristics of the 99mTc- and 188Re-labeled monopotassium salt of 1-hydroxyethylidenediphosphonic acid (KHEDP) in rats showed that the level of accumulated activity at 5 min and 1 and 3 h after i.v. injection of 1
Publikováno v:
Pharmaceutical Chemistry Journal. 42:301-307
Means and methods for monitoring the quality of the new Russian radiopharmaceutical preparation, 99mTc-HEDP, for radionuclide diagnosis of bone pathology were developed, along with reagents for its preparation.