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Autor:
Robert Jaffard, D Higueret, Paul Higueret, V Enderlin, Véronique Pallet, Serge Alfos, Marianne Husson
Publikováno v:
Nutritional neuroscience. 3(3)
Recent studies have revealed a novel and unexpected role of vitamin A, via its nuclear receptors, in higher cognitive functions. We examined, in mouse brain, the impact of vitamin A status on the level of retinoic acid nuclear receptor (RAR and RXR)
Autor:
V Enderlin, Véronique Pallet
Publikováno v:
Oléagineux, Corps gras, Lipides, Vol 18, Iss 2, Pp 68-75 (2011)
Oléagineux, Corps Gras, Lipides
Oléagineux, Corps Gras, Lipides, John Libbey Eurotext, 2011, 18 (2), pp.68-75. ⟨10.1051/ocl.2011.0375⟩
Oléagineux, Corps Gras, Lipides
Oléagineux, Corps Gras, Lipides, John Libbey Eurotext, 2011, 18 (2), pp.68-75. ⟨10.1051/ocl.2011.0375⟩
International audience; To date, convergent data on the role of retinoic acid in the mature brain have established that this molecule, which acts as a hormone, helps to preserve cerebral plasticity by controlling dendritic spine density as well as hi
Publikováno v:
Journal of Neurochemistry. 79:859-867
Brain ageing is associated with a dysregulation of intracellular calcium (Ca2+) homeostasis which leads to deficits in Ca2+-dependent signalling pathways and altered neuronal functions. Given the crucial role of neurogranin/RC3 (Ng) in the post-synap
Autor:
V Enderlin, Nadirah Ghenimi, Véronique Pallet, Marianne Husson, Serge Alfos, André Delacourte, Paul Higueret
Publikováno v:
Neurobiology of Disease, Vol 23, Iss 1, Pp 1-10 (2006)
Recent data have revealed that disruption of vitamin A signaling observed in Alzheimer's disease (AD) leads to a deposition of beta-amyloid (Abeta). The aim of this study was to precise the role of vitamin A and its nuclear receptors (RAR) in the pro
Autor:
Véronique Pallet, V Enderlin, F. Mingaud, Marianne Husson, Paul Higueret, Catherine Féart, Serge Alfos
Publikováno v:
Neurobiology of Aging. 26:729-738
Given the important role of retinoids and thyroid hormone for optimal brain functioning and the tenuous relationship between retinoic acid (RA) and triiodothyronine (T3) signalings, we compared the effects of RA or T3 administrations on RA and T3 nuc
Autor:
Catherine Féart, Serge Alfos, Paul Higueret, Véronique Pallet, V Enderlin, Julie Vallortigara
Publikováno v:
Scopus-Elsevier
Recent data have shown that fine regulation of retinoid mediated gene expression is fundamentally important for optimal brain functioning in aged mice. Nevertheless, alteration of the thyroid hormone signalling pathway may be a limiting factor, which
Publikováno v:
Molecular Brain Research. 123:7-17
Our previous data showed that vitamin A deficiency (VAD) induces, in whole brain, a reduced amount of mRNA for brain retinoic acid (RA) and triiodothyronine (T3) nuclear receptors (i.e., RAR, RXR, and TR, respectively), which is accompanied by reduce
Autor:
Véronique Pallet, Aline Marighetto, Robert Jaffard, Paul Higueret, Nicole Etchamendy, V Enderlin
Publikováno v:
Behavioural Brain Research. 145:37-49
Vitamin A and its derivatives, the retinoids, have recently been reported to be implicated in the synaptic plasticity of the hippocampus and in cognitive functions. Acting via transcription factors, retinoids can regulate gene expression via their nu
Publikováno v:
British Journal of Nutrition. 90:191-198
Recent studies have revealed that retinoids play an important role in the adult central nervous system and cognitive functions. Previous investigations in mice have shown that vitamin A deficiency (VAD) generates a hypo-expression of retinoic acid (R