Zobrazeno 1 - 10
of 255
pro vyhledávání: '"V E Koteliansky"'
Publikováno v:
Proceedings of the National Academy of Sciences. 96:12719-12724
Transforming growth factor β (TGF-β) is a well characterized cytokine that appears to play a major role in directing the cellular response to injury, driving fibrogenesis, and, thus, potentially underlying the progression of chronic injury to fibro
Publikováno v:
Regulatory Peptides. 77:177-183
Many extracellular matrix proteins contain the tripeptide sequence arginine-glycine-aspartate (RGD). This RGD motif is recognized by integrins, a family of adhesion receptors present on vascular smooth muscle cells. In the present study, we examined
Autor:
V. E. Koteliansky, Frederick C. Monson, Saverio Sartore, Alan J. Wein, Giacomo Passerini-Glazel, M. Roelofs, R. M. Levin
Publikováno v:
Journal of Applied Physiology. 78:1432-1441
Partial outlet obstruction of rabbit bladder induces serosal thickening and smooth muscle (SM) cell hypertrophy that are accompanied by phenotypic changes in the expression of cytoskeletal and cytocontractile proteins. In the present study, we compar
Autor:
E B Corben, E P Moiseyeva, P A Weller, I Jasinska, Bipin Patel, V E Koteliansky, David R. Critchley, N I Zhidkova
Publikováno v:
Journal of Biological Chemistry. 268:4318-4325
The human vinculin gene contains 22 exons ranging in size from 71 base pairs (bp) to 303 bp (average 155 bp) with the exception of exon 22 which contains 144 bp of coding sequence and 1848 bp of 3‘-untranslated sequence including two polyadenylatio
The origin of myofibroblasts in stromal reaction has been a subject of controversy. To address this question definitively, we developed techniques for purification and characterization of major stromal cell types. We defined a panel of markers that c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1f459d3151a3ddba5500d2eae4df7f4
https://europepmc.org/articles/PMC295570/
https://europepmc.org/articles/PMC295570/
Publikováno v:
The Journal of Cell Biology
We have examined the cell-specific expression of two fibronectin isoforms, EIIIA and EIIIB, during experimental hepatic fibrosis induced by ligation of the biliary duct. AT the mRNA level, EIIIA and EIIIB were undetectable in normal liver but express
Autor:
V E Koteliansky, Guido Tarone, Fiorella Balzac, Y V Balabanov, Alexey M. Belkin, Fiorella Altruda, Lorenzo Silengo
Publikováno v:
The Journal of Cell Biology
We have previously described a variant form of the integrin beta 1 subunit (beta 1B)1 characterized by an altered sequence at the cytoplasmic domain. Using polyclonal antibodies to a synthetic peptide corresponding to the unique sequence of the beta
Role of the I-9 and III-1 modules of fibronectin in formation of an extracellular fibronectin matrix
Publikováno v:
The Journal of biological chemistry. 266(17)
Cultured fibroblasts bind soluble protomeric fibronectin and mediate its conversion to insoluble disulfide-bonded multimers. The disulfide-bonded multimers are deposited in fibrillar pericellular matrix. Antifibronectin monoclonal antibodies were ana
Publikováno v:
The Journal of biological chemistry. 265(22)
To describe phenotypic changes of human aortic smooth muscle cells (SMCs), proportion of smooth muscle and nonmuscle variants of actin, myosin heavy chains (MHCs), vinculin, and caldesmon, during prenatal and several months of postnatal development w
Autor:
E B Corben, V E Koteliansky, Bipin Patel, P A Weller, David R. Critchley, G J Price, N K Spurr, E P Ogryzko, N I Zhidkova
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 87(15)
We have determined the complete sequence of human vinculin, a cytoskeletal protein associated with cell-cell and cell-matrix junctions. Comparison of human and chicken embryo vinculin sequences shows that both proteins contain 1066 amino acids and ex