Zobrazeno 1 - 10
of 82
pro vyhledávání: '"V E, Steele"'
Autor:
V. E. Steele, D. Bagheri, D. A. Balentine, C. W. Boone, R. Mehta, M. A. Morse, S. Sharma, C. C. Sigman, G. D. Stoner, M. J. Wargovich, J. H. Weisburger, S. Zhu, G. J. Kelloff
Publikováno v:
Experimental Biology and Medicine. 220:210-212
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e649b63e6b65f1b77328bad24fae95d6
https://doi.org/10.3181/00379727-220-44367
https://doi.org/10.3181/00379727-220-44367
Publikováno v:
Anticancer research. 21(6A)
One of the approaches in chemoprevention to prevent or delay the progression of precancerous lesions, is to apply chemopreventive agents that can potentially block angiogenesis. A quantitative in vivo angiogenesis inhibition assay was developed to te
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::bd86a5bbd1555488fc3f176711f15a2e
https://pubmed.ncbi.nlm.nih.gov/11911254
https://pubmed.ncbi.nlm.nih.gov/11911254
Autor:
S M, D'Ambrosio, R E, Gibson-D'Ambrosio, G, Wani, B, Casto, G E, Milo, G J, Kelloff, V E, Steele
Publikováno v:
Anticancer research. 21(5)
Aberrant expression of Ki67, p53 and RARbeta are characteristic of many tumor types including those of the oral cavity. Chemopreventive agents may act by modulating their expression to more normal levels.The effects of 21 chemopreventive agents on th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2c7f28dfc4d33c8c6390fee826c37dc3
https://pubmed.ncbi.nlm.nih.gov/11848477
https://pubmed.ncbi.nlm.nih.gov/11848477
Publikováno v:
Cancer epidemiology, biomarkersprevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology. 10(6)
The synthetic retinoid, N-(4-hydroxyphenyl)retinamide (4HPR), which is currently being evaluated in clinical trials for cancer prevention and therapy, inhibits the growth of a variety of malignant cells through induction of apoptosis. However, in the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::73aeb6b4cb8b1f862fe65c6287563878
https://pubmed.ncbi.nlm.nih.gov/11401908
https://pubmed.ncbi.nlm.nih.gov/11401908
Publikováno v:
Anticancer research. 21(2A)
The efficacy of difluoromethylornithine (DFMO) as a chemopreventive agent has been tested in vitro using a human epidermal cell (HEC) assay with growth inhibition and involucrin induction as endpoints. Suppression of polyamine content is currently be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e8170fe6e1fe864aefe01a06c0c3fcb1
https://pubmed.ncbi.nlm.nih.gov/11396157
https://pubmed.ncbi.nlm.nih.gov/11396157
Autor:
C J, Grubbs, R A, Lubet, A T, Koki, K M, Leahy, J L, Masferrer, V E, Steele, G J, Kelloff, D L, Hill, K, Seibert
Publikováno v:
Cancer research. 60(20)
Epidemiological studies have shown that nonsteroidal anti-inflammatory drugs (NSAIDs) may have a role in the prevention of human cancers. A number of preclinical studies have also suggested that inhibition of cyclooxygenase (COX) with NSAIDs has an a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e21fc7992b9a64a10afb39df0ccf7b97
https://pubmed.ncbi.nlm.nih.gov/11059745
https://pubmed.ncbi.nlm.nih.gov/11059745
Publikováno v:
Anticancer research. 20(4)
Squamous cell carcinoma (SCC) of the oral cavity is a multistep process, progressing through a series of discrete, irreversible and complementary alterations in genes that control cell growth, death, and differentiation. In the premalignant state, th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0ddedde5973c5ea6a9c57ad15e114566
https://pubmed.ncbi.nlm.nih.gov/10953285
https://pubmed.ncbi.nlm.nih.gov/10953285
Autor:
M J, Wargovich, A, Jimenez, K, McKee, V E, Steele, M, Velasco, J, Woods, R, Price, K, Gray, G J, Kelloff
Publikováno v:
Carcinogenesis. 21(6)
We assessed the effects of 78 potential chemopreventive agents in the F344 rat using two assays in which the inhibition of carcinogen-induced aberrant crypt foci (ACF) in the colon was the measure of efficacy. In both assays ACF were induced by the c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6a29fbc85a6269a59df2dbf8117d7d0d
https://pubmed.ncbi.nlm.nih.gov/10837003
https://pubmed.ncbi.nlm.nih.gov/10837003
Publikováno v:
Anticancer research. 20(1A)
Continuous exposure to low doses of potentially mutagenic and carcinogenic chemicals over the human lifetime makes the identification of agents, which could reduce the ensuing risk of cancer, beneficial. The Human Epidermal Cell (HEC) Assay includes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9997c7749a9a803058fe0b76299c4455
https://pubmed.ncbi.nlm.nih.gov/10769631
https://pubmed.ncbi.nlm.nih.gov/10769631
Publikováno v:
Methods in cell science : an official journal of the Society for In Vitro Biology. 22(1)
The Human Epithelial Cell Cytotoxicity (HECC) Assay for determining organ specific cytotoxicity uses human epithelial cells from eight different human tissues, including: skin, mammary, prostate, renal, bronchial, oral, ecto-cervix, and liver. Althou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a1b4be242c198e2637c464e02a0a6263
https://pubmed.ncbi.nlm.nih.gov/10650329
https://pubmed.ncbi.nlm.nih.gov/10650329