Zobrazeno 1 - 10 of 158 pro vyhledávání: '"V C Jordan"'
2
Delayed triggering of oestrogen induced apoptosis that contrasts with rapid paclitaxel-induced breast cancer cell death
Autor: V C Jordan, Surojeet Sengupta, Ping Fan, Ifeyinwa Obiorah
Publikováno v: British Journal of Cancer
Background: Oestrogen (E2) induces apoptosis in long-term E2-deprived MCF7 cells (MCF7:5C). Taxanes have been used extensively in the treatment of early and advanced breast cancer. We have interrogated the sequence of events that involve the apoptoti
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f92d8fa535c4f744174f05f534c81e5
https://pubmed.ncbi.nlm.nih.gov/24548860
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3
In vitro study of the effect of raloxifene on lipid metabolism compared with tamoxifen
Autor: Y. Hozumi, Mikihiko Kawano, V. C. Jordan
Publikováno v: European Journal of Endocrinology. 143:427-430
OBJECTIVE: Tamoxifen and raloxifene, selective estrogen receptor modulators, decrease serum concentrations of total cholesterol; however, the effect of these drugs on triglyceride metabolism is unclear. In the present study, we investigated the in vi
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::beb9fc045b203fd0e4776e1f7ec7857c
https://doi.org/10.1530/eje.0.1430427
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5
Effects of the Antiestrogens Tamoxifen, Toremifene, and ICI 182,780 on Endometrial Cancer Growth
Autor: R M, O'Regan, A, Cisneros, G M, England, J I, MacGregor, H D, Muenzner, V J, Assikis, M M, Bilimoria, M, Piette, Y P, Dragan, H C, Pitot, R, Chatterton, V C, Jordan
Publikováno v: JNCI Journal of the National Cancer Institute. 90:1552-1558
Background Tamoxifen has been shown to promote the growth of human endometrial tumors implanted in athymic mice, and it has been associated with a twofold to threefold increase in endometrial cancer. Toremifene, a chlorinated derivative of tamoxifen,
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5113053f0e2b383e004dfd92452299a3
https://doi.org/10.1093/jnci/90.20.1552
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8
Hormonal Treatment of Advanced Breast Cancer
Autor: V. C. Jordan, C. Tellez
Publikováno v: Surgical Oncology Clinics of North America. 4:751-777
Endocrine therapy for breast cancer has been used for almost a century, but because of the enormous success of tamoxifen there has been a resurgence of interest by the pharmaceutical industry to develop new and innovative endocrine therapies. Overall
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::7134c579d41773297748b6c92330f8d1
https://doi.org/10.1016/s1055-3207(18)30428-9
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9
Tamoxifen: Toxicities and Drug Resistance During the Treatment and Prevention of Breast Cancer
Autor: V C Jordan
Publikováno v: Annual Review of Pharmacology and Toxicology. 35:195-211
Tamoxifen, a nonsteroidal antiestrogen, is the endocrine therapy of choice for all stages of breast cancer. There are six million women-years of experience with tamoxifen, and the drug has produced survival advantages in node-positive and node-negati
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc12d1ae66c7ec07819e81fdfafb3295
https://doi.org/10.1146/annurev.pa.35.040195.001211
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