Zobrazeno 1 - 10
of 42
pro vyhledávání: '"V C Broudy"'
Publikováno v:
Blood. 88:75-81
The phenotypes of mice that harbor a defect in the genes encoding either stem cell factor (SCF) or its receptor, c-kit, indicate that this ligand/receptor pair is necessary for maintenance of normal hematopoiesis in the adult. Our objective was to de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4a0e14fc96f262ed917aa8870d0488f
https://doi.org/10.1182/blood.v88.1.75.bloodjournal88175
https://doi.org/10.1182/blood.v88.1.75.bloodjournal88175
Publikováno v:
International journal of STDAIDS. 23(2)
Tobacco smoking and HIV infection increase the risk of epidermoid anal cancer (EAC). No published studies have examined smoking and EAC outcomes, and the literature is discrepant regarding outcomes of HIV-positive patients with EAC. The goal of this
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb510d3105790c3c130ece90f8a984fd
https://pubmed.ncbi.nlm.nih.gov/22422679
https://pubmed.ncbi.nlm.nih.gov/22422679
Publikováno v:
Blood. 82:436-444
Stem cell factor (SCF) acts in synergy with other growth factors such as erythropoietin (Epo), granulocyte-macrophage colony-stimulating factor (GM-CSF), or interleukin-3 (IL-3), to stimulate the growth of primitive hematopoietic cells. Because of th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c146cbcd3b36d12a7cc81f8cbbd55bb0
https://doi.org/10.1182/blood.v82.2.436.bloodjournal822436
https://doi.org/10.1182/blood.v82.2.436.bloodjournal822436
Publikováno v:
Blood. 80:1679-1684
Human kit ligand (KL), also known as stem cell factor (SCF), steel factor, or mast cell growth factor, is a recently identified hematopoietic growth factor whose receptor is the product of the c-kit proto-oncogene. Alternative splicing of the pre-mRN
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c5579d55ccffbdf6888147bc96b78d4
https://doi.org/10.1182/blood.v80.7.1679.1679
https://doi.org/10.1182/blood.v80.7.1679.1679
Publikováno v:
Blood. 80:374-381
Human stem cell factor (SCF) acts in the presence of other growth factors to stimulate the growth of primitive hematopoietic progenitor cells. These effects are performed by activation of the SCF receptor, c- kit. Because of the potential use of SCF
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb49936465a90c56798806e58fe66fba
https://doi.org/10.1182/blood.v80.2.374.374
https://doi.org/10.1182/blood.v80.2.374.374
Publikováno v:
Blood. 80:60-67
Stem cell factor (SCF) acts in concert with lineage-specific growth factors to stimulate the growth of hematopoietic colonies. To determine if neoplastic human hematopoietic cells would also respond to SCF, we cultured marrow mononuclear cells from 2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0dd2e093c733914b23c332785c862941
https://doi.org/10.1182/blood.v80.1.60.bloodjournal80160
https://doi.org/10.1182/blood.v80.1.60.bloodjournal80160
Publikováno v:
Blood. 79:3159-3167
A mouse antihuman monoclonal IgG2a antibody, termed stem cell receptor- 1 (SR-1), specific for a determinant of the c-kit ligand receptor (KR), was used as an immunologic probe to analyze KR expression by human bone marrow hematopoietic progenitor ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::670e7f9da5c470cc9860cf4f369e5d25
https://doi.org/10.1182/blood.v79.12.3159.3159
https://doi.org/10.1182/blood.v79.12.3159.3159
Autor:
V C, Broudy, N, Lin, K M, Zsebo, N C, Birkett, K A, Smith, I D, Bernstein, T, Papayannopoulou
Publikováno v:
Blood. 79:338-346
Stem cell factor (SCF) stimulates the growth of burst-forming unit- erythroid (BFU-E) and colony-forming unit granulocyte-macrophage (CFU- GM) by binding to a specific cell surface receptor. The receptor for SCF is encoded by the protooncogene c-kit.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4bdc24832b5a44b88006521c387e7993
https://doi.org/10.1182/blood.v79.2.338.bloodjournal792338
https://doi.org/10.1182/blood.v79.2.338.bloodjournal792338
Publikováno v:
Blood. 77:2577-2582
Erythropoietin (Epo) regulates the growth and differentiation of erythroid cells by binding to a specific receptor. We characterized the native Epo receptor on erythroleukemia cell lines by ligand blotting. Solubilized cell membrane proteins were sep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bfa531c8a11609ddfbe93c48608df8ce
https://doi.org/10.1182/blood.v77.12.2577.bloodjournal77122577
https://doi.org/10.1182/blood.v77.12.2577.bloodjournal77122577
Publikováno v:
The Journal of Immunology. 144:3789-3794
Monocyte products including TNF and IL-1 can stimulate hemopoietic growth factor production in vitro and in vivo. Endotoxin-resistant C3H/HeJ mice have a cellular defect in the regulation of TNF production and provide a model in which to examine the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9f2cf6fe1db87ecfafe9b9d7ecd811da
https://doi.org/10.4049/jimmunol.144.10.3789
https://doi.org/10.4049/jimmunol.144.10.3789