Zobrazeno 1 - 10
of 27
pro vyhledávání: '"V C, Maino"'
Autor:
Douglas R. Murray, Davide Serrano, Peter K. Gregersen, Cheryl A. Armstrong, V. C. Maino, Franak Batliwalla, Stuart Macphail, Barbara A. Bateman, John C. Ansel
Publikováno v:
Molecular Medicine. 4:783-794
The development of effective adjuvant therapies for the treatment of high-risk melanoma patients is critical for the prevention of metastatic disease and improvement of patient survival. Active specific immunotherapy has been tested as an adjuvant tr
Autor:
D Buck, D Dilley, Ronald C. Kennedy, V C Maino, Kenton L. Lohman, Roberta Attanasio, Patrick Kanda
Publikováno v:
Journal of Biological Chemistry. 266:14611-14619
A panel of mouse monoclonal anti-CD4 antibodies was characterized in terms of idiotypic expression by using specific anti-idiotypic antibody (anti-Id) reagents generated in rabbits immunized with anti-Leu3a, a monoclonal anti-CD4 which inhibits the h
Autor:
M A, Suni, S A, Ghanekar, D W, Houck, H T, Maecker, S B, Wormsley, L J, Picker, R B, Moss, V C, Maino
Publikováno v:
European journal of immunology. 31(8)
CD4(+)CD8(dim) T cells represent a minor subset of the total CD3(+) T cell population in peripheral blood. Although transient and persistent expansions of these cells have been reported in both healthy and diseased individuals, the functional propert
Publikováno v:
Journal of clinical immunology. 20(6)
The use of flow cytometry to study the functional responses of T cells by immunofluorescent staining for intracellular cytokines and other markers is a growing field of clinical interest. In this article, we describe methods for the rapid evaluation
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 6(3)
The detection of tumor-specific T cells in immunized cancer patients usually relies on lengthy and difficult CTL assays; we now report on flow cytometry to detect the intracellular cytokines interleukin 2 (IL-2), IL-4, IFN-gamma, and tumor necrosis f
Autor:
F M, Batliwalla, B A, Bateman, D, Serrano, D, Murray, S, Macphail, V C, Maino, J C, Ansel, P K, Gregersen, C A, Armstrong
Publikováno v:
Molecular medicine (Cambridge, Mass.). 4(12)
BACKGROUND: The development of effective adjuvant therapies for the treatment of high-risk melanoma patients is critical for the prevention of metastatic disease and improvement of patient survival. Active specific immunotherapy has been tested as an
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 161(10)
CD4+ memory T cells coordinate immune responses against viruses and other pathogens via the Ag-induced secretion of potent effector cytokines. The efficacy of these responses depends on both the overall number of pathogen-specific memory T cells and
Autor:
V C, Maino, L J, Picker
Publikováno v:
Cytometry. 34(5)
Methods for analysis of T cell function have traditionally relied upon measurements of proliferation or cytokine expression in bulk cultures of PBMC in long term incubations with polyclonal mitogens or putative antigen. These techniques suffer from t
Autor:
S P, Perfetto, T E, Hickey, P J, Blair, V C, Maino, K F, Wagner, S, Zhou, D L, Mayers, D, St Louis, C H, June, J N, Siegel
Publikováno v:
Cytometry. 30(1)
Peripheral blood mononuclear cells from many asymptomatic HIV-infected patients exhibit defects in cytokine production and impaired proliferative responses in vitro but the mechanisms underlying this subclinical immune deficiency are controversial. T
Autor:
L J, Picker, M K, Singh, Z, Zdraveski, J R, Treer, S L, Waldrop, P R, Bergstresser, V C, Maino
Publikováno v:
Blood. 86(4)
The array of cytokines produced by T cells in effector sites is a primary means by which these cells mediate host defense. It is well recognized that cloned T cells are heterogeneous with regard to cytokine synthesis and, thus, in their ability to me