Zobrazeno 1 - 10 of 14 pro vyhledávání: '"V B, Waits"'
2
Berberine derivatives as antileishmanial drugs
Autor: J. K. Lovelace, Jonathan L. Vennerstrom, Daniel L. Klayman, W. L. Hanson, V. B. Waits
Publikováno v: Antimicrobial Agents and Chemotherapy. 34:918-921
Berberine, a quaternary alkaloid, and several of its derivatives were tested for efficacy against Leishmania donovani and Leishmania braziliensis panamensis in golden hamsters. Tetrahydroberberine was less toxic and more potent than berberine against
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0aa4418c60fcd4d3aa86dd078455940
https://doi.org/10.1128/aac.34.5.918
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3
1-(Substituted)benzyl-5-aminoimidazole-4-carboxamides are potent orally active inhibitors ofTrypanosoma cruzi in mice
Autor: T.J. Ikeler, Arthur A. Patchett, Robert A. Reamer, Karst Hoogsteen, V. B. Waits, William L. Hanson, Matthew J. Wyvratt, L. H. Peterson, John C. Chabala, L.G. Payne, M. H. Fisher
Publikováno v: Experientia. 47:51-53
1-(Substituted)benzyl-5-aminoimidazole-4-carboxamides are potent orally active inhibitors of Trypanosoma cruzi infections in mice. The most active compounds are the 1-(4-chlorobenzyl)- and 1-(3,4-dichlorobenzyl)-analogs (L-153,094 [2] and L-153,153 [
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81965014278260545da92d85bb1a677c
https://doi.org/10.1007/bf02041250
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4
Chagas' disease: a search for treatment and a question--should the disease be of military concern?
Autor: K E, Kinnamon, B T, Poon, J P, Scovill, W L, Hanson, V B, Waits
Publikováno v: Military medicine. 162(8)
If military forces are required to operate in areas that are endemic for Chagas' disease, the occupation should be of critical concern. These areas, located in Central and South America, are many. The matter is of particular importance because no sui
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::706db7a7b3006329a3e43eb6da08661e
https://pubmed.ncbi.nlm.nih.gov/9271903
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5
Activity of amphotericin B cholesterol dispersion (Amphocil) in experimental visceral leishmaniasis
Autor: V B Waits, Jonathan D. Berman, W L Chapman, G. Ksionski, W. L. Hanson
Publikováno v: Antimicrobial agents and chemotherapy. 36(9)
Standard therapy of human visceral leishmaniasis with parenteral pentavalent antimonial agents is generally curative but has the disadvantages of a 28-day treatment course, occasional treatment failures, and toxicity. The antifungal and antileishmani
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8338a834872ba617563ac6002c80b31e
https://pubmed.ncbi.nlm.nih.gov/1416890
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6
Development of Leishmania (Viannia) panamensis lesions and relationship of numbers of amastigotes to lesion area on antimony-treated and untreated hamsters
Autor: W L, Hanson, W L, Chapman, V B, Waits, J K, Lovelace
Publikováno v: The Journal of parasitology. 77(5)
Young adult (60-70-g) male golden hamsters (Mesocricetus auratus) each were injected intradermally at the dorsal base of the tail with 15 x 10(6) promastigotes of Leishmania (Viannia) panamensis (MHOM/PA/83/WR539), and progression and regression of s
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::78a21c67e5e5d8462dd97f785bfd33ee
https://pubmed.ncbi.nlm.nih.gov/1919929
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7
The influence of gonadectomy of host on parasitemia and mortality of mice infected with Trypanosoma cruzi
Autor: W L, Chapman, W L, Hanson, V B, Waits
Publikováno v: The Journal of parasitology. 61(2)
Male CF1 mice were more susceptible to acute infections of Trypanosoma cruzi than female mice as evidenced by significantly greater maximum mean parasitemia of approximately 8.9 times 10-6 per ml in males as compared to 1.5 times 10-6 per ml in femal
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::1dc3df60bbf28e947d4f54f788469800
https://pubmed.ncbi.nlm.nih.gov/805227
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8
Liposomes in leishmaniasis: therapeutic effects of antimonial drugs, 8-aminoquinolines, and tetracycline
Autor: Edgar A. Steck, W. L. Hanson, Glenn M. Swartz, Willie L. Chapman, Larry D. Hendricks, Carl R. Alving, V B Waits
Publikováno v: Life sciences. 26(26)
This study investigated the role of liposomes in changing the pharmacological efficacy of anti-leishmanial drugs in hamsters infected with visceral leishmaniasis. Enhanced anti-leishmanial activity could be accounted for only by liposome-encapsulated
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dfc5589655707766742cc4a76c1303b0
https://pubmed.ncbi.nlm.nih.gov/7401920
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10
Leishmaniasis: in search of new chemotherapeutic agents
Autor: K E, Kinnamon, E A, Steck, P S, Loizeaux, W L, Chapman, V B, Waits, W L, Hanson
Publikováno v: American journal of veterinary research. 41(3)
Members of a class of compounds designated lepidines (8-amino-6-methoxy-4-methylquinoline derivatives) were tested in a hamster-Leishmania donovani model and found to have activity many-fold that of a reference drug meglumine antimoniate. One of them
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::32112729b24919ad4627ccc19a784209
https://pubmed.ncbi.nlm.nih.gov/7369615
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