Zobrazeno 1 - 10
of 46
pro vyhledávání: '"V B, Prozorovskiĭ"'
Publikováno v:
Eksperimental'naia i klinicheskaia farmakologiia. 73(8)
Bizerine-oxalate of hexamethylene-bic-[N-methylcarbamic acid-3-(2-dimethylaminomethyl)pyridyl ether] exhibits the properties of acetylcholine esterase (AChE) inhibitor, being comparable in this respect in in vitro tests to aminostigmine. Bizerine is
Autor:
V B, Prozorovskiĭ, V G, Skopichev
Publikováno v:
Eksperimental'naia i klinicheskaia farmakologiia. 68(3)
Toxic action of some organophosphorus cholinesterase inhibitors (including phosphacol) on the state of microvessels was studied in rats. Cholinesterase was found in endotheliocytes and it was established that phosphacol inhibited this enzyme. This wa
Publikováno v:
Morfologiia (Saint Petersburg, Russia). 118(4)
Poisoning with phosphacol causes dose--dependent decrease of blood flow speed in small vessels of mesoappendix. Administration of LD50 of phosphacole results in blood stagnation, simultaneous blood pressure fall, which leads to death of part of the a
Publikováno v:
Eksperimental'naia i klinicheskaia farmakologiia. 63(4)
Dimedrol and pipolphen, but not loratadine, increase efficacy of the atropine and dipiroxime treatment of mice--an antidote prophylaxis against their intoxication with phosphacol and aminostigmine. The results of experiments confirm a hypothesis that
Publikováno v:
Voprosy meditsinskoi khimii. 45(6)
A series of aminostigmin derivatives with various substituents at nitrogen in the second position of the pyridine ring, has been tested. The efficacy of preventing the death of mice poisoned by armine in five of the seven substances correlates with t
Autor:
V G, Skopichev, V B, Prozorovskiĭ
Publikováno v:
Eksperimental'naia i klinicheskaia farmakologiia. 62(2)
Scanning electron microscopy showed that the capillary endothelial cells of rats poisoned by O,O-dimethyl-O(2,2-dichlorvinyl) phosphate swell and become wrinkled, while some of the cells acquire fenestrae. In 24 h. these changes become weaker. Mass d
Publikováno v:
Morfologiia (Saint Petersburg, Russia). 112(6)
By method of scanning electron microscopy erythrocyte structure was studied in rats in carbophos poisoning. Following up to 76% acetylcholinesterase inhibition with distinct symptoms of intoxication nearly 30% of erythrocytes were deformed and tended
Publikováno v:
Biokhimiia (Moscow, Russia). 61(4)
The properties of aminostigmine in comparison with those of other carbamate inhibitors of cholinesterases have been studied in vitro using potentiometric titration and Ellman methods. The bimolecular constants of the inhibition rate of acetyl-, butyr
Publikováno v:
Eksperimental'naia i klinicheskaia farmakologiia. 59(1)
The results of application of cholinesterase inhibitors, aminostigmin and galantamin, for treatment of acute poisoning with cyclodol, dimedrol, and solutan of moderately grave condition are presented. Aminostigmin was shown to exhibit the more pronou
Autor:
V B, Prozorovskiĭ, A V, Sazonova
Publikováno v:
Eksperimental'naia i klinicheskaia farmakologiia. 58(5)
This investigation has been carried out on albino mice. In the first series of experiments, we determined the dependence of LD50 of aminostigmine on different doses of 10 cholinolytics, and conversely, the dependence of LD50 of cholinolytics on amino