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Publikováno v:
Reproduction. 97:91-100
Previous studies in this laboratory have demonstrated the presence of a peptide that inhibits granulosa cell proliferation in medium sized follicles. This peptide was produced after 72-96 h of exposure to diethylstilboestrol (DES). This study analyse
Autor:
T. M. Mills, William C. Allsbrook, Everett Anderson, Joseph E. Martinez, Cooley G. Pantazis, I. M. Rao, John R. Beck, B. A. Conway, V. B. Mahesh
Publikováno v:
Reproduction. 91:521-530
Immature rats were treated with diethylstilboestrol (DES) or pregnant mares' serum gonadotropin (PMSG) and forward angle light-scatter (FALS) and 90 degrees light-scatter (90 degrees LS) signals were used to measure the size and the granularity (inte
Publikováno v:
Biology of reproduction. 62(6)
The purpose of this study was to identify factors from astrocytes that can regulate LHRH neurosecretion. Exposure of LHRH-secreting (GT1-7) cells to conditioned media (CM) from C6 glial cells and hypothalamic astrocytes (HA) stimulated LHRH release.
Autor:
G R, Mora, V B, Mahesh
Publikováno v:
Steroids. 64(9)
Several studies have documented that androgens have the ability to autoregulate their own receptor levels; however, the mechanism of such autoregulation remains poorly understood. Along these lines, our laboratory has shown that testosterone increase
Publikováno v:
Endocrinology. 140(10)
In a previous publication we provided evidence of a novel neuronal pathway for the control of GnRH secretion by bradykinin. The action of bradykinin appeared to be exerted through the bradykinin B2 receptor. In this study we demonstrated that the bra
Publikováno v:
Biology of reproduction. 58(5)
In this study we examined the roles of progesterone (P4) and estradiol-17beta (E2) in regulation of the P4 receptor (PR) and estrogen receptor (ER) in the decidua basalis (DB) during stromal cell proliferation and regression (Days 10 and 14 of pregna
Publikováno v:
Neuroendocrinology. 66(4)
Recent work has demonstrated that glutamate functions as a major transmitter involved in the regulation of gonadotropin-releasing hormone (GnRH) and luteinizing hormone (LH) secretion in female animals, although the specific receptors and mechanisms
Publikováno v:
Biology of reproduction. 57(3)
This study examines the distribution and abundance of progesterone receptors (PR) and estrogen receptors (ER) in the decidua basalis (DB) during proliferation (Days 8-12 of gestation) and regression (Days 14-21) in the rat. Stromal cells of the DB an
Publikováno v:
Biology of reproduction. 54(6)
Estrogens have been reported to exert both stimulatory and inhibitory effects on granulosa cell function. Previous studies from our laboratory showed that 12 h after administration of diethylstilbestrol (DES; a synthetic estrogen), FSH-stimulated gra