Zobrazeno 1 - 8
of 8
pro vyhledávání: '"V A, Zagorevskiĭ"'
Autor:
O A, Gol'dina, T A, Moskvitina, E M, Gankina, A Z, Kirkel', N S, Kamyshanskaia, K I, Lopatina, T V, Sokolova, V A, Zagorevskiĭ, A V, Val'dman, V Z, Gorkin
Publikováno v:
Biulleten' eksperimental'noi biologii i meditsiny. 111(3)
The effect on deamination of serotonine, dopamine, tiramine and 2-phenylamine of benzamide derivatives befol, moclobemide and LIS-641 was studied. Befol and moclobemide are inhibitors of serotonine deaminating activity of MAO. The different sensitivi
Publikováno v:
Biulleten' eksperimental'noi biologii i meditsiny. 101(2)
Carrageenan is shown to cause acute inflammation in mucous membrane of hamster cheek pouch and rat hind foot. Rutin has no effect on the pathological process in the cheek pouch, and arrests the first phase of inflammation in the foot. Esculamine has
Publikováno v:
Biulleten' eksperimental'noi biologii i meditsiny. 104(10)
The reversible MAO-A inhibitor moclobemide (5 mg/kg) was shown to prevent seizures in rats during exposure to toxic oxygen (6 ata). Benzamide derivatives increased the latent period of oxygen seizures and decreased the lethality following hyperbaric
Publikováno v:
Biulleten' eksperimental'noi biologii i meditsiny. 97(5)
The differences in the pharmacological effects of R(+)- and S(-)-isomers of the atypical antidepressant viloxazin were discovered in two behavioral models. The S(-)-isomer appeared 5 times as active as the R(+)-isomer under acute administration. In c
Publikováno v:
Biulleten' eksperimental'noi biologii i meditsiny. 102(8)
The ability of moclobamide and other benzamide derivatives to inhibit the activity of monoamine oxidase in the rat brain was studied. Distinct effects of these compounds on the deamination of serotonin and norepinephrine (MAO-A substrates); 2-phenyle
[Experimental parkinsonian syndrome in rats induced by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine]
Publikováno v:
Biulleten' eksperimental'noi biologii i meditsiny. 105(4)
Systemic administration of high doses of MPTP caused transient bradykinesia, "freezing" episodes, head tremors, hunching of the back and peripheral autonomic effects. Neurological syndrome was clearly dose-dependent. It has been established that Park
Publikováno v:
Biulleten' eksperimental'noi biologii i meditsiny. 107(1)
Lipid peroxidation was investigated in adult (8-10 months of age) rat striatum with Parkinsonian syndrome induced by MPTP and its metabolite MPP+. MPTP 20 mg/kg i.p. 4 doses) produced a slight enhancement of lipid peroxidation and significant increas
Publikováno v:
Farmakologiia i toksikologiia. 49(1)
It was shown in experiments on rats that intraabdominal administration of silver nitrate solution induces peritonitis and the subplantar administration of histamine, serotonin and prostaglandin E2 leads to an acute paw edema. Preliminary subcutaneous