Zobrazeno 1 - 9
of 9
pro vyhledávání: '"V A, Proĭnova"'
Autor:
Z I, Zholdakova, G N, Krasovskiĭ, Kh Kh, Khamidulina, G I, Rozhnov, V A, Proĭnova, E A, Loĭko
Publikováno v:
Gigiena i sanitariia. (3)
Results of experimental substantiation of hygienic standards of 30 drugs in water and analysis of published data showed that drugs should be referred to highly hazardous pollutants of the environment. Criteria and indexes of pharmacologic activity we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e3182d259272eb2d17ec04ac60dc8acd
https://pubmed.ncbi.nlm.nih.gov/7635349
https://pubmed.ncbi.nlm.nih.gov/7635349
Publikováno v:
Farmakologiia i toksikologiia. 48(1)
A study was made of the blastomogenic activity of dioxydin, a new antibacterial broad-action drug. Administration of dioxydin in doses of 20-100 mg/kg (exceeding 2-10-fold the therapeutic dose for humans) to mice and rats intragastrically for 18 mont
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::34665e5a1fa6242bf69af0e0cf7f55f8
https://pubmed.ncbi.nlm.nih.gov/3979542
https://pubmed.ncbi.nlm.nih.gov/3979542
Publikováno v:
Farmakologiia i toksikologiia. 48(6)
A single administration of dimebon (800 mg/kg) to rats per os (2/3 of the LD50 isoeffective for females) raises the preimplantation death, whereas pipolphen increases the intrauterine lethality and inhibits the development of fetuses. Pipolphen in a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::63043815e206ee6b63e0a4ccdce478ba
https://pubmed.ncbi.nlm.nih.gov/2867932
https://pubmed.ncbi.nlm.nih.gov/2867932
Publikováno v:
Farmakologiia i toksikologiia. 42(4)
The parameters of bonafton pharmacokinetics (absorption, distribution, excretion) have been studied in male Wistar rats at single enteral and intraperitoneal administration. With these routes of administration daily resorption amounts to 26 and 100%,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3a121384d138803d895b15836f650185
https://pubmed.ncbi.nlm.nih.gov/477964
https://pubmed.ncbi.nlm.nih.gov/477964
Publikováno v:
Farmakologiia i toksikologiia. 43(3)
The toxicity of the original drug bonaphthon was studied in pregnant and nonpregnant mice and rats given the drug orally and intraperitoneally. In a dose of 100 mg/kg bonaphthon had no toxic effect on pregnant rats after 4-time administration per os,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ebffad74dc26036603461d8d6b80c09a
https://pubmed.ncbi.nlm.nih.gov/7449974
https://pubmed.ncbi.nlm.nih.gov/7449974
Publikováno v:
Farmakologiia i toksikologiia. 43(4)
The first generation progeny of rats received days 10-13 of pregnancy a new antiviral drug bonaphthon (400 mg/kg) which exerts a toxic effect on females. The progeny did not show postnatal death or reduction of the life span. Moreover, no impairment
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6ac20f09ca5a02ae168781ce4d40bf7b
https://pubmed.ncbi.nlm.nih.gov/7439376
https://pubmed.ncbi.nlm.nih.gov/7439376
Publikováno v:
Farmakologiia i toksikologiia. 43(2)
The ability of 14C-bonafton to penetrate the placental bar was studied in female Wistar rats. The drug was shown to penetrate through the placenta in insignificant amounts. The maximal quantities of the drug which entered the fetuses proper during th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a91bd385f2fdec07b2a65d395d7b1a48
https://pubmed.ncbi.nlm.nih.gov/7002601
https://pubmed.ncbi.nlm.nih.gov/7002601
Publikováno v:
Farmakologiia i toksikologiia. 48(3)
The antihistaminic drug dimebon was subjected to toxicological study. It was demonstrated that as regards the level of the mean lethal doses dimebon can be attributed to little toxic substances. Administration of the drug in the doses approximating t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::041769eb2bdd43840b912b27c60aed23
https://pubmed.ncbi.nlm.nih.gov/2863167
https://pubmed.ncbi.nlm.nih.gov/2863167
Publikováno v:
Farmakologiia i toksikologiia. 45(4)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::bb10d39e912904fe578622acc244e7e4
https://pubmed.ncbi.nlm.nih.gov/6751867
https://pubmed.ncbi.nlm.nih.gov/6751867