Zobrazeno 1 - 10
of 22
pro vyhledávání: '"V A, Linscombe"'
Autor:
M. Sue Marty, Kenneth E. Stebbins, Narendra P. Singh, B. Bhaskar Gollapudi, Julie K. Passage, V. Ann Linscombe
Publikováno v:
Toxicologic Pathology. 38:244-257
If p53 is essential to eliminate damaged spermatogenic cells, then mutagen exposure in the absence of p53 would increase sperm containing damaged DNA. p53 knockout (−/−, NULL) and wild-type (+/+, WT) mice (five/group) were exposed to ethylnitroso
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db4abcc1aa952f0cb4809fb03cacb6b3
https://doi.org/10.1177/0192623309357947
https://doi.org/10.1177/0192623309357947
Publikováno v:
Mutation Research Letters. 347:9-12
The mutagenic activity of the aliphatic epoxide isoamylene oxide (2-methyl-2,3-epoxybutane) is not readily detectable in the standard Ames test. In this study, the clastogenic potential of isoamylene oxide was evaluated using an in vitro mammalian ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a2bba9fcc0be897f27455eb1f22f052
https://doi.org/10.1016/0165-7992(95)90025-x
https://doi.org/10.1016/0165-7992(95)90025-x
Publikováno v:
Mutation Research/Genetic Toxicology. 342:25-36
The genetic toxicity of chlorpyrifos [O,O,-diethyl-O-(3,5,6-trichloro-2- pyridinyl)phosphorothioate, C.A.S. Number: 2921-88-2)], an organophosphate insecticide, was examined by employing several end points such as gene mutations in bacteria (Ames tes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf23a6a4203b34124cc59de2082f86c3
https://doi.org/10.1016/0165-1218(95)90087-x
https://doi.org/10.1016/0165-1218(95)90087-x
Publikováno v:
Journal of the American College of Toxicology. 12:155-159
DGBE was evaluated in a forward gene mutation assay at the HGPRT locus of CHO cells in culture and in an in vivo mouse bone marrow micronucleus test for cytogenetic damage. DGBE did not elicit a positive response in the CHO/HGPRT assay when tested up
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e2ca25ac2a49c478447764fe554cbb15
https://doi.org/10.3109/10915819309140634
https://doi.org/10.3109/10915819309140634
Autor:
Shawn D. Seidel, Barney R. Sparrow, V. Ann Linscombe, H. Lynn Kan, Melissa R. Schisler, W.T. Stott, B. Bhaskar Gollapudi
Publikováno v:
Mutagenesis. 19(3)
Treatment of cells with genotoxic chemicals is expected to set into motion a series of events including gene expression changes to cope with the damage. We have investigated gene expression changes in L5178Y TK(+/-) mouse lymphoma cells in culture fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09beee568b81835170d92473c4545724
https://pubmed.ncbi.nlm.nih.gov/15123784
https://pubmed.ncbi.nlm.nih.gov/15123784
Evaluation of the potential of triethanolamine to alter hepatic choline levels in female B6C3F1 mice
Publikováno v:
Toxicological sciences : an official journal of the Society of Toxicology. 79(2)
Triethanolamine (TEA), a widely used nongenotoxic alcohol-amine, has recently been reported to cause an increased incidence of liver tumors in female B6C3F1 mice, but not in males nor in Fischer 344 rats. Choline deficiency induces liver cancer in ro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a2a3ac7f863a4b7b289ead741d36c0b
https://pubmed.ncbi.nlm.nih.gov/15056812
https://pubmed.ncbi.nlm.nih.gov/15056812
Publikováno v:
In Vitro Cellular & Developmental Biology - Animal. 29:350-352
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62596e72a1a1d8a5a63d5c4fcc76b37f
https://doi.org/10.1007/bf02633979
https://doi.org/10.1007/bf02633979
Publikováno v:
In Vitro Cellular & Developmental Biology - Animal. 27:603-605
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8959f6f7e3e9416eec7b5de671fa0c8f
https://doi.org/10.1007/bf02631102
https://doi.org/10.1007/bf02631102
Publikováno v:
Mutation research. 444(1)
2,4-Dichlorophenoxyacetic acid and its derivatives (collectively known as 2,4-D) are herbicides used to control a wide variety of broadleaf and woody plants. The genetic toxicity of an ester (2,4-D 2-butoxyethylester) and two salts (2,4-D isopropylam
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4c0acf1fc348fa27fd2ed4ac11b3ac7
https://pubmed.ncbi.nlm.nih.gov/10477357
https://pubmed.ncbi.nlm.nih.gov/10477357
Autor:
B. Bhaskar Gollapudi, Anil K. Sinha, Raymond E. Flake, V. Ann Linscombe, Kenneth M. Bodner, Mary L. McClintock
Publikováno v:
Canadian Journal of Genetics and Cytology. 26:528-531
Spontaneously occurring cytogenetic aberrations were compared in 48- and 72-h human lymphocyte cultures from a group of 20 normal male volunteers. Mitotic indices for both cultures times were also evaluated. BUdR (5-bromo, 2-deoxyuridine) labelled me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8be2ac9a37e3d41c101028c688b6bffd
https://doi.org/10.1139/g84-084
https://doi.org/10.1139/g84-084