Breaking the DNA by soft X-rays in the water window reveals the scavenging and temporal behaviour of ·OH radicals

Autor: Luděk Vyšín, Przemyslaw Wachulak, Věra Hájková, Marie Davídková, Henryk Fiedorowicz, Andrzej Bartnik, Libor Juha

Publikováno v: Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)

Abstract A laser-plasma source emitting photons with energies in the water window spectral range has been used to reveal the radiation chemical yields of single-strand breaks in plasmid DNA as a function of ·OH radical scavenger concentration. Direc

Externí odkaz: https://doaj.org/article/4d9a6f00977b4b49b3813766c460cbb1

Ion emission from warm dense matter produced by irradiation with a soft x-ray free-electron laser

Autor: Josef Krása, Tomáš Burian, Věra Hájková, Jaromír Chalupský, Šimon Jelínek, Kateřina Frantálová, Michal Krupka, Zuzana Kuglerová, Sushil Kumar Singh, Vojtěch Vozda, Luděk Vyšín, Michal Šmíd, Pablo Perez-Martin, Marion Kühlman, Juan Pintor, Jakub Cikhardt, Matthias Dreimann, Dennis Eckermann, Felix Rosenthal, Sam M. Vinko, Alessandro Forte, Thomas Gawne, Thomas Campbell, Shenyuan Ren, YuanFeng Shi, Trevor Hutchinson, Oliver Humphries, Thomas Preston, Mikako Makita, Motoaki Nakatsutsumi, Xiayun Pan, Alexander Köhler, Marion Harmand, Sven Toleikis, Katerina Falk, Libor Juha

Publikováno v: Matter and Radiation at Extremes, Vol 9, Iss 1, Pp 016602-016602-14 (2024)

We report on an experiment performed at the FLASH2 free-electron laser (FEL) aimed at producing warm dense matter via soft x-ray isochoric heating. In the experiment, we focus on study of the ions emitted during the soft x-ray ablation process using

Externí odkaz: https://doaj.org/article/e22751757963401395f172acdd53d731

Investigating the interaction of x-ray free electron laser radiation with grating structure

Autor: Mitsuru Nagasono, Jérôme Gaudin, Nicola Coppola, Stefan Möller, Henry N. Chapman, Kai Tiedtke, Karel Saksl, R.A. Loch, Ryszard Sobierajski, Sven Toleikis, Harald Sinn, Vĕra Hajkova, Ludĕk Vysin, Michael Störmer, Germano Galasso, Pavol Sovák, Jaromír Chalupský, Joachim Schulz, Jacek Krzywinski, Shafagh Dastjani Farahani, Marek Jurek, Marion Harmand, Libor Juha, Saša Bajt, Tomáš Burian, Thomas Tschentscher, C. Ozkan

Publikováno v: Optics letters, 37(15), 3033-3035. The Optical Society
Gaudin, J.; Ozkan, C.; Chalupsky, J.; Bajt, S.; Burian, T.; Vysin, L.; CoppolaN.; Dastjani-Farahani, S.; Chapman, H.N.; Galasso, G.; Hajkova, V.; Harmand, M.; Juha, L.; Jurek, M.; Loch, R.A.; Moeller, S.; Nagasono, M.; Stoermer, M.; Sinn, H.; Saksl, K.; Sobierajski, R.; Schulz, J.; Sovak, P.; Toleikis, S.; Tiedtke, K.; Tschentscher, T.; Krzywinski, J.: Investigating the interaction of x-ray free electron laser radiation with grating structure. In: Optics Letters. Vol. 37 (2012) 15, 3033-3035. (DOI: 10.1364/OL.37.003033)
Optics Letters, 37, 3033-3035
Optics letters 37(15), 3033-3035 (2012). doi:10.1364/OL.37.003033
ResearcherID

The interaction of free electron laser pulses with grating structure is investigated using 4.6 +/- 0.1 nm radiation at the FLASH facility in Hamburg. For fluences above 63.7 +/- 8.7 mJ/cm(2), the interaction triggers a damage process starting at the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63c766aa5f08b361d961b1fcc55fe014
https://doi.org/10.1364/ol.37.003033

Vaccinia Virus Expressing Interferon Regulatory Factor 3 Induces Higher Protective Immune Responses against Lethal Poxvirus Challenge in Atopic Organism

Autor: Hana Pilna, Vera Hajkova, Jarmila Knitlova, Jana Liskova, Jana Elsterova, Zora Melkova

Publikováno v: Viruses, Vol 13, Iss 10, p 1986 (2021)

Vaccinia virus (VACV) is an enveloped DNA virus from the Orthopoxvirus family, various strains of which were used in the successful eradication campaign against smallpox. Both original and newer VACV-based replicating vaccines reveal a risk of seriou

Externí odkaz: https://doaj.org/article/2d2d3ad0d00e4e25a44872f292c3763d

Development of eczema vaccinatum in atopic mouse models and efficacy of MVA vaccination against lethal poxviral infection.

Autor: Jarmila Knitlova, Vera Hajkova, Ludek Voska, Jana Elsterova, Barbora Obrova, Zora Melkova

Publikováno v: PLoS ONE, Vol 9, Iss 12, p e114374 (2014)

Smallpox vaccine based on live, replicating vaccinia virus (VACV) is associated with several potentially serious and deadly complications. Consequently, a new generation of vaccine based on non-replicating Modified vaccinia virus Ankara (MVA) has bee

Externí odkaz: https://doaj.org/article/95cf1131874d4f02b079df8ec3709b31