Zobrazeno 1 - 10
of 46
pro vyhledávání: '"Vítor E, Santo"'
Autor:
Fernanda Silva, Filipa Coelho, Ana Peixoto, Pedro Pinto, Carmo Martins, Ann-Sophie Frombach, Vítor E. Santo, Catarina Brito, António Guimarães, Ana Félix
Publikováno v:
Cancer Cell International, Vol 22, Iss 1, Pp 1-17 (2022)
Highlights IPOLFG-SOC43 cell line represents the heterogeneity of Epithelial Ovarian Cancer Genetic alterations in cancer cells confer a selective advantage 3D cultures preserve the phenotypical features of the original tumor
Externí odkaz:
https://doaj.org/article/71cd59d565b44b1b83724cd94dc06196
Cysteine allows ovarian cancer cells to adapt to hypoxia and to escape from carboplatin cytotoxicity
Autor:
Sofia C. Nunes, Cristiano Ramos, Filipa Lopes-Coelho, Catarina O. Sequeira, Fernanda Silva, Sofia Gouveia-Fernandes, Armanda Rodrigues, António Guimarães, Margarida Silveira, Sofia Abreu, Vítor E. Santo, Catarina Brito, Ana Félix, Sofia A. Pereira, Jacinta Serpa
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-17 (2018)
Abstract Ovarian cancer is the second most common gynaecologic malignancy and the main cause of death from gynaecologic cancer, due to late diagnosis and chemoresistance. Studies have reported the role of cysteine in cancer, by contributing for hydro
Externí odkaz:
https://doaj.org/article/f0b992f1098b47c99c388b7bc002b953
Autor:
Rita Mendes, Teresa F. Mendes, Marta Teixeira, Vítor E. Santo, Catarina Brito, Sofia Abreu, Fernanda Silva, Erwin R. Boghaert, Ana Félix
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-13 (2020)
Scientific Reports
Scientific Reports
Ovarian carcinoma (OvC) remains a major therapeutic challenge due to its propensity to develop resistance after an initial response to chemotherapy. Interactions of tumour cells with the surrounding microenvironment play a role in tumour survival, in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::622a0dec04fc000c2d2b3b73968fd6f1
http://link.springer.com/article/10.1038/s41598-020-76291-z
http://link.springer.com/article/10.1038/s41598-020-76291-z
Autor:
Ana Paula Sousa, Luis Redondo, Vítor E. Santo, Sandro Casaleiro, Margarida Serra, D. Rego, Sofia Abreu
Publikováno v:
TECHNOLOGY. :40-45
Platelets are blood components with high biomedical potential due to their physiological role in wound healing and their rich growth factor content. This paper describes proof-of-concept experiments aimed to produce a new blood-derived product by app
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6c15da438f9fd89dfb14c96868021fc0
https://doi.org/10.1142/s2339547819500031
https://doi.org/10.1142/s2339547819500031
Publikováno v:
Polymers, Vol 8, Iss 2, p 28 (2016)
Magnetic nanoparticles (MNPs) are attractive tools to overcome limitations of current regenerative medicine strategies, demonstrating potential to integrate therapeutic and diagnostic functionalities in highly controlled systems. In traditional tissu
Externí odkaz:
https://doaj.org/article/b0cf4a7b9ad94faebdf8088f6fe8a7f0
Autor:
Kedar S. Vaidya, Xin Lu, Anatol Oleksijew, Jonathan Hickson, Tamar Uziel, Catarina Brito, Vítor E. Santo, Kelly Foster-Duke, Erwin R. Boghaert, Thomas McGonigal, Paul Hessler, Michael J. Mitten
Publikováno v:
Neoplasia (New York, N.Y.)
Neoplasia: An International Journal for Oncology Research, Vol 19, Iss 9, Pp 695-706 (2017)
Neoplasia: An International Journal for Oncology Research, Vol 19, Iss 9, Pp 695-706 (2017)
Improving the congruity of preclinical models with cancer as it is manifested in humans is a potential way to mitigate the high attrition rate of new cancer therapies in the clinic. In this regard, three-dimensional (3D) tumor cultures in vitro have
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68b0ab943e8860a065c8e3374d23ecc1
http://europepmc.org/articles/PMC5545812
http://europepmc.org/articles/PMC5545812
Autor:
Suzana, Vidic, Marta F, Estrada, Kjersti, Gjerde, Vítor E, Santo, Annika, Osswald, Michaël, Barbier, Yolanda T, Chong, Wolfgang, Sommergruber, Ronald, de Hoogt, Catarina, Brito, Ralph, Graeser
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 1888
PREDECT, a European IMI consortium, has assumed the task to generate robust 2D and 3D culture platforms. Protocols established for 2D and 3D monoculture and stromal coculture models of increasing complexity (spheroid, stirred-tank bioreactor, Matrige
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c1ebea1f2c21d147bd3a7c356cbb4ad9
https://pubmed.ncbi.nlm.nih.gov/30519938
https://pubmed.ncbi.nlm.nih.gov/30519938
Autor:
Vítor E. Santo, Marta Estrada, Suzana Vidic, Michaël Barbier, Kjersti Gjerde, Yolanda T. Chong, Wolfgang Sommergruber, Ronald de Hoogt, Catarina Brito, Ralph Graeser, Annika Osswald
Publikováno v:
Methods in Molecular Biology ISBN: 9781493988907
PREDECT, a European IMI consortium, has assumed the task to generate robust 2D and 3D culture platforms. Protocols established for 2D and 3D monoculture and stromal coculture models of increasing complexity (spheroid, stirred-tank bioreactor, Matrige
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3a0617cec040cbfde6a90a4d98a3bfe1
https://doi.org/10.1007/978-1-4939-8891-4_1
https://doi.org/10.1007/978-1-4939-8891-4_1
Autor:
Manuela E. Gomes, Susana Faria, Pedro S. Babo, Rui L. Reis, Pedro P. Carvalho, Vítor E. Santo
Publikováno v:
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Injectable calcium phosphate cements have been used as a valid alternative to autologous bone grafts for bone augmentation with the additional advantage of enabling minimally invasive implantation procedures and for perfectly fitting the tissue defec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f5b19868577754335897cd62dc4d4e36
https://doi.org/10.1177/0885328216669474
https://doi.org/10.1177/0885328216669474
Autor:
Nuno M. Neves, João F. Mano, Vítor E. Santo, Daniela F. Coutinho, Cláudia Correia, Pedro S. Babo, Miguel Amador, Rui L. Reis, Manuela E. Gomes, Bárbara Cunha
Publikováno v:
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Gradients of physical and chemical cues are characteristic of specific tissue microenvironments and contribute toward morphogenesis and tissue regeneration upon injury. Recent advances on microfluidics and hydrogel manipulation raised the possibility
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d8fad079b788a13ff41d522eafda96c
https://doi.org/10.1021/acs.biomac.6b00150
https://doi.org/10.1021/acs.biomac.6b00150