Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Vítor Carmona"'
Autor:
Ana Teresa Barros-Viegas, Vítor Carmona, Elisabete Ferreiro, Joana Guedes, Ana Maria Cardoso, Pedro Cunha, Luís Pereira de Almeida, Catarina Resende de Oliveira, João Pedro de Magalhães, João Peça, Ana Luísa Cardoso
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 19, Iss , Pp 1219-1236 (2020)
Alzheimer’s disease (AD) is the most common form of dementia worldwide, characterized by progressive memory impairment, behavioral changes, and, ultimately, loss of consciousness and death. Recently, microRNA (miRNA) dysfunction has been associated
Externí odkaz:
https://doaj.org/article/0a6fe9c2a19a4a2f9dc6dd4e1645a878
Autor:
Helena Leal, João Cardoso, Patrícia Valério, Marta Quatorze, Vítor Carmona, Janete Cunha-Santos, Luís Pereira de Almeida, Cláudia Pereira, Cláudia Cavadas, Pedro Gomes
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 12, p 6790 (2022)
Nonalcoholic fatty liver disease (NAFLD), a condition strongly associated with obesity and insulin resistance, is characterized by hepatic lipid accumulation and activation of the endoplasmic reticulum (ER) stress response. The sirtuin 2 (SIRT2) prot
Externí odkaz:
https://doaj.org/article/ff12a3b980a54a80aedc36c1dba46ad9
Autor:
Carlos A, Matos, Vítor, Carmona, Udaya-Geetha, Vijayakumar, Sara, Lopes, Patrícia, Albuquerque, Mariana, Conceição, Rui Jorge, Nobre, Clévio, Nóbrega, Luís Pereira, de Almeida
Publikováno v:
Advances in experimental medicine and biology. 1049
Polyglutamine diseases are hereditary degenerative disorders of the nervous system that have remained, to this date, untreatable. Promisingly, investigation into their molecular etiology and the development of increasingly perfected tools have contri
Autor:
Lea J. Hachigian, Vitor Carmona, Robert J. Fenster, Ruth Kulicke, Adrian Heilbut, Annie Sittler, Luís Pereira de Almeida, Jill P. Mesirov, Fan Gao, Eric D. Kolaczyk, Myriam Heiman
Publikováno v:
Cell Reports, Vol 21, Iss 10, Pp 2688-2695 (2017)
Summary: Alteration of corticostriatal glutamatergic function is an early pathophysiological change associated with Huntington’s disease (HD). The factors that regulate the maintenance of corticostriatal glutamatergic synapses post-developmentally
Externí odkaz:
https://doaj.org/article/e36073e028884b6d9f350553ebe04c9b
Autor:
Janete Cunha-Santos, Joana Duarte-Neves, Vitor Carmona, Leonard Guarente, Luís Pereira de Almeida, Cláudia Cavadas
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-14 (2016)
SIRTs have been reported to provide neuroprotective actions in polyglutamine diseases, and are linked to the beneficial effects of caloric restrictive diets. Here, the authors show caloric restriction improves behavioural and neuropathological defici
Externí odkaz:
https://doaj.org/article/a4a2d4276c134fcebdf4609415741326