Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Vít Zvoníček"'
Autor:
Jan Jirát, Jan Rohlíček, Jakub Kaminský, Tomáš Jirkal, Luděk Ridvan, Eliška Skořepová, Vít Zvoníček, Michal Dušek, Miroslav Šoóš
Publikováno v:
IUCrJ, Vol 10, Iss 2, Pp 210-219 (2023)
The transformation processes of non-solvated ibrutinib into a series of halogenated benzene solvates are explored in detail here. The transformation was studied in real time by X-ray powder diffraction in a glass capillary. Crystal structures of chlo
Externí odkaz:
https://doaj.org/article/043c446e1ced43629bfa9c1f839c4b63
Publikováno v:
IUCrJ, Vol 6, Iss 1, Pp 145-151 (2019)
Multicomponent solid forms of active pharmaceutical ingredients represent a modern method of tuning their physicochemical properties. Typically, salts are the most commonly used multicomponent solid form in the pharmaceutical industry. More than 38%
Externí odkaz:
https://doaj.org/article/b461e56ae8684f46aaeb551806f5b233
Autor:
Sreela Ramesh, Eliška Skořepová, Václav Eigner, Vaisakh Chelod Paingad, Vít Zvoníček, Petr Kužel, Miroslav Šoóš
Publikováno v:
Crystal Growth & Design. 23:168-179
Autor:
Vít Zvoníček, Ondřej Stoklasa, Dan Trunov, Ivona Sedlářová, Tereza Boleslavská, Jiří Němeček, Miloslav Lhotka, Pavel Žvátora, Miroslav Šoóš
Publikováno v:
Organic Process Research & Development. 26:111-122
Autor:
Martin Babor, Luděk Ridvan, Michal Dušek, Jan Jirát, Miroslav Soos, Eliška Skořepová, Vít Zvoníček
Publikováno v:
Crystal Growth & Design. 20:5785-5795
Search for new multicomponent solid forms has become a key step in pharmaceutical drug development. Apremilast, a poorly soluble API used for the treatment of psoriatic arthritis, was used as a mod...
Publikováno v:
Powder Diffraction. 35:160-165
This paper describes a new flow-through capillary sample holder that allows the in situ study of re-solvation processes. The holder can be aligned to the goniometer's center using two perpendicular micrometric tables that move in y and z directions.
Publikováno v:
Crystal Growth & Design. 18:1315-1326
In this paper, we present a comprehensive crystallographic study of Ibrutinib polymorphs and their behavior. Three neat polymorphs (A, B, and C) and a methanol solvate (F) were obtained and characterized. The structures of forms A, C, and F were solv
Autor:
Eliska Skorepova, Růžena Vlasáková, Igor Čerňa, Marcela Tkadlecova, Vít Zvoníček, Michal Dušek
Publikováno v:
Journal of Molecular Structure. 1148:22-27
Ixazomib citrate is a very recently approved anti-cancer drug. Until now, to the best of our knowledge, no one has been able to solve any crystal structures of this compound. In this work, we present the crystal structures of two isostructural solvat
Autor:
Luděk Ridvan, Argyro Chatziadi, Eliška Skořepová, Miroslav Soos, Jan Čejka, Jan Jirát, Vít Zvoníček, Jan Rohlíček
Publikováno v:
Journal of Crystal Growth. 562:126085
Lacosamide is used in the adjunctive treatment of partial-onset seizures and diabetic neuropathic pain. Up-to-date, only one polymorph has been described. Our aim was to explore the thermal phase behavior of this compound. When heated, no transformat
Publikováno v:
Crystal Growth & Design. 17:3116-3127
A search for new solid forms of an active pharmaceutical ingredient (API) is an integral part of the drug product development process. The studied compound, Ibrutinib, is a recently approved anticancer drug. The main aim of this study was to search f