Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Víctor Mangas-Sanjuan"'
Publikováno v:
Pharmaceutics, Vol 15, Iss 2, p 601 (2023)
The development of second-entry topical products is hampered by several factors. The excipient composition should be similar to the reference product because excipients may also contribute to efficacy. Conventional pharmacokinetic bioequivalence stud
Externí odkaz:
https://doaj.org/article/52a4d5d5634d499cb5aa518a28c6be29
Autor:
Gledys Reynaldo Fernández, Eduardo M. Fernández-Sánchez, Mayra Ramos Suzarte, Daniel Amaro, Roberto Menéndez, Helena Colom, Víctor Mangas-Sanjuan, Gilberto Castañeda, Jorge Duconge, Braulio Jiménez-Vélez, Niurys de Castro Suárez, Carmen Viada, Joaquín Solazábal, María de los A. Bécquer
Publikováno v:
Anales de la Academia de Ciencias de Cuba, Vol 10, Iss 3 (2020)
Introducción. La farmacometría es una disciplina científica vibrante que está conformada por el ciclo de excelencia: integración, innovación e impacto. Objetivo: Evaluar diferentes enfoques farmacométricos en tres productos biotecnológicos cu
Externí odkaz:
https://doaj.org/article/2596f3b4e5dc4692a1fa199da1097f0c
Autor:
Laura García-Quintanilla, Andrea Luaces-Rodríguez, María Gil-Martínez, Cristina Mondelo-García, Olalla Maroñas, Víctor Mangas-Sanjuan, Miguel González-Barcia, Irene Zarra-Ferro, Pablo Aguiar, Francisco J. Otero-Espinar, Anxo Fernández-Ferreiro
Publikováno v:
Pharmaceutics, Vol 11, Iss 8, p 365 (2019)
Intravitreal administration of anti-vascular endothelial growth factor (VEGF) antibodies has become the standard treatment for Age-Related Macular Degeneration; however, the knowledge of their pharmacokinetics is limited. A comprehensive review of th
Externí odkaz:
https://doaj.org/article/97ba863170094df488b83912357c7b69
Publikováno v:
Journal of Pharmacy & Pharmacognosy Research. 11:160-178
Context: Pharmacokinetic studies play a fundamental role in making informed decisions during the drug development stage and fulfilling regulatory agencies' requirements for drug approval. Disposition profiles of plasma drug concentrations over time c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::45b782240adf789e58edfbe040f2e080
https://doi.org/10.56499/jppres22.1472_11.1.160
https://doi.org/10.56499/jppres22.1472_11.1.160
Autor:
Enrique Bandín-Vilar, Laura García-Quintanilla, Ana Castro-Balado, Irene Zarra-Ferro, Miguel González-Barcia, Manuel Campos-Toimil, Víctor Mangas-Sanjuan, Cristina Mondelo-García, Anxo Fernández-Ferreiro
Publikováno v:
Clinical pharmacokinetics. 61(6)
In recent years, many studies on population pharmacokinetics of linezolid have been conducted. This comprehensive review aimed to summarize population pharmacokinetic models of linezolid, by focusing on dosage optimization to maximize the probability
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73927009f96b36e611f7754b4b2da0a6
https://pubmed.ncbi.nlm.nih.gov/35699914
https://pubmed.ncbi.nlm.nih.gov/35699914
Autor:
Karine Rodríguez-Fernández, Javier Zarzoso-Foj, Marina Saez-Bello, Almudena Mateu-Puchades, Antonio Martorell-Calatayud, Matilde Merino-Sanjuan, Elena Gras-Colomer, Monica Climente-Martí, Victor Mangas-Sanjuan
Publikováno v:
Pharmaceutics, Vol 16, Iss 10, p 1295 (2024)
Background/Objectives: Implementing model-informed precision dosing (MIPD) strategies guided by population pharmacokinetic/pharmacodynamic (PK/PD) models could enhance the management of inflammatory diseases such as psoriasis. However, the extent of
Externí odkaz:
https://doaj.org/article/ccfe46024c91474d8e2ad06b8f5c444d
Autor:
Gloria M. Alfosea-Cuadrado, Javier Zarzoso-Foj, Albert Adell, Alfonso A. Valverde-Navarro, Eva M. González-Soler, Víctor Mangas-Sanjuán, Arantxa Blasco-Serra
Publikováno v:
Pharmaceutics, Vol 16, Iss 8, p 1101 (2024)
(1) Background: Fibromyalgia syndrome (FMS) is a chronic pain condition with widespread pain and multiple comorbidities, for which conventional therapies offer limited benefits. The reserpine-induced myalgia (RIM) model is an efficient animal model o
Externí odkaz:
https://doaj.org/article/028b71294bfb441f95582e292ce5f55d
Autor:
Andreu Mañez-Asensi, Mª Jesús Hernández, Víctor Mangas-Sanjuán, Ana Salvador, Matilde Merino-Sanjuán, Virginia Merino
Publikováno v:
Pharmaceutics, Vol 16, Iss 6, p 749 (2024)
The demonstration of bioequivalence proposed in the European Medicines Agency’s (EMA’s) draft guideline for topical products with the same qualitative and quantitative composition requires the confirmation of the internal structure equivalence. T
Externí odkaz:
https://doaj.org/article/97d15faa0ae34de4b5a15a4db6904e23
Autor:
Karine Rodríguez-Fernández, Gledys Reynaldo-Fernández, Stephanie Reyes-González, Camila de las Barreras, Leyanis Rodríguez-Vera, Cornelis Vlaar, Jean-Christophe M. Monbaliu, Torsten Stelzer, Jorge Duconge, Victor Mangas-Sanjuan
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 170, Iss , Pp 115977- (2024)
Warfarin, an oral anticoagulant, has been used for decades to prevent thromboembolic events. The complex interplay between CYP2C9 and VKORC1 genotypes on warfarin PK and PD properties is not fully understood in special sub-groups of patients. This st
Externí odkaz:
https://doaj.org/article/0a608cf64a12471a9399d00137492f06
Autor:
Aymara Sancho-Araiz, Zinnia P Parra-Guillen, Jean Bragard, Sergio Ardanza, Victor Mangas-Sanjuan, Iñaki F Trocóniz
Publikováno v:
PLoS Computational Biology, Vol 19, Iss 10, p e1011507 (2023)
Mathematical modeling of unperturbed and perturbed tumor growth dynamics (TGD) in preclinical experiments provides an opportunity to establish translational frameworks. The most commonly used unperturbed tumor growth models (i.e. linear, exponential,
Externí odkaz:
https://doaj.org/article/83e6686c29df4c62b1781b73a62be77b