Zobrazeno 1 - 10
of 202
pro vyhledávání: '"Víctor M Pérez-García"'
Autor:
Beatriz Ocaña-Tienda, Odelaisy León-Triana, Julián Pérez-Beteta, Juan Jiménez-Sánchez, Víctor M Pérez-García
Publikováno v:
PLoS Computational Biology, Vol 20, Iss 1, p e1011400 (2024)
Metastasis is the process through which cancer cells break away from a primary tumor, travel through the blood or lymph system, and form new tumors in distant tissues. One of the preferred sites for metastatic dissemination is the brain, affecting mo
Externí odkaz:
https://doaj.org/article/2bd8fbc966424f39b6a82867cd1784dc
Autor:
Thibault Delobel, Luis E Ayala-Hernández, Jesús J Bosque, Julián Pérez-Beteta, Salvador Chulián, Manuel García-Ferrer, Pilar Piñero, Philippe Schucht, Michael Murek, Víctor M Pérez-García
Publikováno v:
PLoS Computational Biology, Vol 19, Iss 11, p e1011208 (2023)
Low-grade gliomas are primary brain tumors that arise from glial cells and are usually treated with temozolomide (TMZ) as a chemotherapeutic option. They are often incurable, but patients have a prolonged survival. One of the shortcomings of the trea
Externí odkaz:
https://doaj.org/article/9789aca29d0f4731af94951119471441
Autor:
Salvador Chulián, Bernadette J Stolz, Álvaro Martínez-Rubio, Cristina Blázquez Goñi, Juan F Rodríguez Gutiérrez, Teresa Caballero Velázquez, Águeda Molinos Quintana, Manuel Ramírez Orellana, Ana Castillo Robleda, José Luis Fuster Soler, Alfredo Minguela Puras, María V Martínez Sánchez, María Rosa, Víctor M Pérez-García, Helen M Byrne
Publikováno v:
PLoS Computational Biology, Vol 19, Iss 8, p e1011329 (2023)
Although children and adolescents with acute lymphoblastic leukaemia (ALL) have high survival rates, approximately 15-20% of patients relapse. Risk of relapse is routinely estimated at diagnosis by biological factors, including flow cytometry data. T
Externí odkaz:
https://doaj.org/article/98c5115ec1784f58bba7bc06fea347cf
Autor:
Juan Jiménez-Sánchez, Álvaro Martínez-Rubio, Anton Popov, Julián Pérez-Beteta, Youness Azimzade, David Molina-García, Juan Belmonte-Beitia, Gabriel F Calvo, Víctor M Pérez-García
Publikováno v:
PLoS Computational Biology, Vol 17, Iss 2, p e1008266 (2021)
Increasingly complex in silico modeling approaches offer a way to simultaneously access cancerous processes at different spatio-temporal scales. High-level models, such as those based on partial differential equations, are computationally affordable
Externí odkaz:
https://doaj.org/article/3bb11e619e0c4f82a65d660754dbaee1
Autor:
Víctor M Pérez-García, Luis E Ayala-Hernández, Juan Belmonte-Beitia, Philippe Schucht, Michael Murek, Andreas Raabe, Juan Sepúlveda
Publikováno v:
PLoS Computational Biology, Vol 15, Iss 7, p e1006778 (2019)
Here we put forward a mathematical model describing the response of low-grade (WHO grade II) oligodendrogliomas (LGO) to temozolomide (TMZ). The model describes the longitudinal volumetric dynamics of tumor response to TMZ of a cohort of 11 LGO patie
Externí odkaz:
https://doaj.org/article/29e21dd3edf94723bd143e190ff9a437
Autor:
Magdalena U Bogdańska, Marek Bodnar, Monika J Piotrowska, Michael Murek, Philippe Schucht, Jürgen Beck, Alicia Martínez-González, Víctor M Pérez-García
Publikováno v:
PLoS ONE, Vol 12, Iss 8, p e0179999 (2017)
Gliomas are the most frequent type of primary brain tumours. Low grade gliomas (LGGs, WHO grade II gliomas) may grow very slowly for the long periods of time, however they inevitably cause death due to the phenomenon known as the malignant transforma
Externí odkaz:
https://doaj.org/article/145b1f2013e64935b98b95a97260fb2c
Autor:
David Molina, Julián Pérez-Beteta, Alicia Martínez-González, Juan Martino, Carlos Velasquez, Estanislao Arana, Víctor M Pérez-García
Publikováno v:
PLoS ONE, Vol 12, Iss 6, p e0178843 (2017)
PURPOSE:Textural measures have been widely explored as imaging biomarkers in cancer. However, their robustness under dynamic range and spatial resolution changes in brain 3D magnetic resonance images (MRI) has not been assessed. The aim of this work
Externí odkaz:
https://doaj.org/article/6dcdd344f4a044129feffc12b9d3b736
Autor:
Araceli Henares-Molina, Sebastien Benzekry, Pedro C Lara, Marcial García-Rojo, Víctor M Pérez-García, Alicia Martínez-González
Publikováno v:
PLoS ONE, Vol 12, Iss 6, p e0178552 (2017)
Grade II gliomas are slowly growing primary brain tumors that affect mostly young patients. Cytotoxic therapies (radiotherapy and/or chemotherapy) are used initially only for patients having a bad prognosis. These therapies are planned following the
Externí odkaz:
https://doaj.org/article/357736aed81c405da17049fd15ad4b8d
Autor:
David Molina, Julián Pérez-Beteta, Alicia Martínez-González, Juan M Sepúlveda, Sergi Peralta, Miguel J Gil-Gil, Gaspar Reynes, Ana Herrero, Ramón De Las Peñas, Raquel Luque, Jaume Capellades, Carmen Balaña, Víctor M Pérez-García
Publikováno v:
PLoS ONE, Vol 11, Iss 8, p e0161484 (2016)
BACKGROUND:Antiangiogenic therapies for glioblastoma (GBM) such as bevacizumab (BVZ), have been unable to extend survival in large patient cohorts. However, a subset of patients having angiogenesis-dependent tumors might benefit from these therapies.
Externí odkaz:
https://doaj.org/article/cc55541fb87d49c3aed14683ab0531ee
Autor:
Beatriz Ocaña-Tienda, Julián Pérez-Beteta, José D. Villanueva-García, José A. Romero-Rosales, David Molina-García, Yannick Suter, Beatriz Asenjo, David Albillo, Ana Ortiz de Mendivil, Luis A. Pérez-Romasanta, Elisabet González-Del Portillo, Manuel Llorente, Natalia Carballo, Fátima Nagib-Raya, Maria Vidal-Denis, Belén Luque, Mauricio Reyes, Estanislao Arana, Víctor M. Pérez-García
Publikováno v:
Scientific Data. 10
Brain metastasis (BM) is one of the main complications of many cancers, and the most frequent malignancy of the central nervous system. Imaging studies of BMs are routinely used for diagnosis of disease, treatment planning and follow-up. Artificial I