Výsledky vyhledávání - "Víctor G. Romera"

The high-mobility group I-Y transcription factor is involved in cerebral ischemia and modulates the expression of angiogenic proteins

Autor: Víctor G. Romera, Judith Mallolas, Mónica Sobrado, Susanna Camós, Mar Castellanos, Carme Gubern, Rocío Rodríguez, Ignacio Lizasoain, J. Serena, María A. Moro

Publikováno v: Neuroscience. 269:112-130

The present study aims to identify transcription factors (TFs) contributing to angiogenesis, a mechanism involved in giving plasticity to the brain, as potential therapeutic targets after cerebral ischemia. The promoter sequences from candidate genes

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0f3b40059a0ef3aa9440087c73afcaf
https://doi.org/10.1016/j.neuroscience.2014.03.036

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miRNA expression is modulated over time after focal ischaemia: up-regulation of miR-347 promotes neuronal apoptosis

Autor: Iván Ballesteros, Carme Gubern, Judith Mallolas, Susanna Camós, Rocío Rodríguez, Ignacio Lizasoain, Mar Castellanos, Víctor G. Romera, Joaquín Serena, Roberto Cañadas, María A. Moro

Publikováno v: FEBS Journal. 280:6233-6246

Despite the large number of molecules reported as being over-expressed after ischaemia, little is known regarding their regulation. miRNAs are potent post-transcriptional regulators of gene expression, and reports have shown differentially miRNA expr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a124b96731d125bee20f9c07e840d35
https://doi.org/10.1111/febs.12546

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Oct-2 transcription factor binding activity and expression up-regulation in rat cerebral ischaemia is associated with a diminution of neuronal damage in vitro

Autor: Víctor G. Romera, Mar Castellanos, Judith Mallolas, Ignacio Lizasoain, Joaquín Serena, Susanna Camós, María A. Moro, Carme Gubern, Rocío Rodríguez, Mónica Sobrado

Publikováno v: Neuromolecular medicine. 16(2)

Brain plasticity provides a mechanism to compensate for lesions produced as a result of stroke. The present study aims to identify new transcription factors (TFs) following focal cerebral ischaemia in rat as potential therapeutic targets. A transient

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::732f97870c2ea295ef45532120a4c00b
https://pubmed.ncbi.nlm.nih.gov/24282026

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Amelioration of Ischemic brain damage by peritoneal dialysis

Autor: Santiago Canals, María A. Moro, Jesus Pacheco, Magdalena Torres, María del Carmen Godino, Ignacio Lizasoain, José Sánchez-Prieto, José Antonio Sánchez-Tomero, Víctor G. Romera, Juan Lerma, José Vivancos

Publikováno v: Biblos-e Archivo. Repositorio Institucional de la UAM
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Ischemic stroke is a devastating condition, for which there is still no effective therapy. Acute ischemic stroke is associated with high concentrations of glutamate in the blood and interstitial brain fluid. The inability of the tissue to retain glut

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b798149c5e0e7b7070fd36f9756cc679
http://hdl.handle.net/10486/663877

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Iron overload, measured as serum ferritin, increases brain damage induced by focal ischemia and early reperfusion

Autor: Jesús M. Pradillo, Juan G. Zarruk, Antoni Dávalos, María A. Moro, Natalia Pérez de la Ossa, Isaac García-Yébenes, Mónica Sobrado, Víctor G. Romera, Ignacio Lizasoain, Ana Moraga

Publikováno v: Neurochemistry international. 61(8)

High levels of iron, measured as serum ferritin, are associated to a worse outcome after stroke. However, it is not known whether ischemic damage might increase ferritin levels as an acute phase protein or whether iron overload affects stroke outcome

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69a77585d3643572dd5e5e0a29e8385a
https://pubmed.ncbi.nlm.nih.gov/23036361

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Neurological tests for functional outcome assessment in rodent models of ischaemic stroke

Autor: Juan G, Zarruk, Isaac, Garcia-Yebenes, Víctor G, Romera, Iván, Ballesteros, Ana, Moraga, María I, Cuartero, Olivia, Hurtado, Mónica, Sobrado, Jesús M, Pradillo, David, Fernandez-Lopez, Joaquín, Serena, Margie, Castillo-Melendez, María A, Moro, Ignacio, Lizasoain

Publikováno v: Revista de neurologia. 53(10)

A critical aspect in all models is the assessment of the final outcome of the modelling procedure. In the case of a focal ischaemic brain injury, apart from the determination of the size of the lesion, another valuable tool is the evaluation of the f

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::d085bfd9d31d980b0d9f1fb4cc40a89a
https://pubmed.ncbi.nlm.nih.gov/22052176

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Validation of housekeeping genes for quantitative real-time PCR in in-vivo and in-vitro models of cerebral ischaemia

Autor: Joaquín Serena, María A. Moro, Víctor G. Romera, Judith Mallolas, Olivia Hurtado, Carme Gubern, Ignacio Lizasoain, Jesús R Morales, Rocío Rodríguez

Publikováno v: BMC Molecular Biology, 2009, vol. 16, núm. 10, p. 57
Articles publicats (D-CM)
DUGiDocs – Universitat de Girona
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BMC Molecular Biology, Vol 10, Iss 1, p 57 (2009)
BMC Molecular Biology

Background Studies of gene expression in experimental cerebral ischaemia models can contribute to understanding the pathophysiology of brain ischaemia and to identifying prognostic markers and potential therapeutic targets. The normalization of relat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a03d9cb520c7f18fc50f00926daee94d
http://hdl.handle.net/10256/16458

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