Zobrazeno 1 - 10
of 343
pro vyhledávání: '"Véronique Préat"'
Publikováno v:
Acta Oncologica, Vol 63, Iss 1 (2024)
Background and purpose: The poor delivery of drugs to infiltrating tumor cells contributes to therapeutic failure in glioblastoma. During the early phase of an anti-angiogenic treatment, a remodeling of the tumor vasculature could occur, leading to a
Externí odkaz:
https://doaj.org/article/50edb14b1902481ebd64930d2cc9edd6
Autor:
Teenesha Chellen, Mathilde Bausart, Pierre Maus, Kevin Vanvarenberg, Nisha Limaye, Véronique Préat, Alessio Malfanti
Publikováno v:
Materials Today Bio, Vol 26, Iss , Pp 101057- (2024)
Glioblastoma (GBM) is an aggressive brain tumor, with a highly immunosuppressive tumor immune microenvironment (TIME). In this work, we investigated the use of the STimulator of INterferon Genes (STING) pathway as an effective means to remodel the GB
Externí odkaz:
https://doaj.org/article/8706bd35314b47c0ba41325e3a3ecd79
Publikováno v:
International Journal of Pharmaceutics: X, Vol 5, Iss , Pp 100147- (2023)
We hypothesized that tocopherol succinate (TOS) and D-α-tocopherol polyethylene2000 succinate (TPGS2000) micelles could work as a drug delivery system while enhancing the anti-cancer efficacy of doxorubicin lauryl hydrazone derivative (DOXC12) for t
Externí odkaz:
https://doaj.org/article/06d9894bef1c411b9e3c30477f7f8848
Publikováno v:
Biomedicines, Vol 12, Iss 5, p 1091 (2024)
(1) Background: Glioblastoma (GB) presents a formidable challenge in neuro-oncology due to its aggressive nature, limited treatment options, and poor prognosis. The blood–brain barrier (BBB) complicates treatment by hindering drug delivery to the t
Externí odkaz:
https://doaj.org/article/f9072b5a0cf5413a95d52c8bfe97f814
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 41, Iss 1, Pp 1-22 (2022)
Abstract Glioblastoma (GBM) treatment has remained almost unchanged for more than 20 years. The current standard of care involves surgical resection (if possible) followed by concomitant radiotherapy and chemotherapy. In recent years, immunotherapy s
Externí odkaz:
https://doaj.org/article/9a1fda044bd3412fba4a59d1669caa3a
Autor:
Jérôme Conq, Nicolas Joudiou, Bernard Ucakar, Kevin Vanvarenberg, Véronique Préat, Bernard Gallez
Publikováno v:
Biomedicines, Vol 11, Iss 7, p 1957 (2023)
Background: While the blood–brain barrier (BBB) is often compromised in glioblastoma (GB), the perfusion and consequent delivery of drugs are highly heterogeneous. Moreover, the accessibility of drugs is largely impaired in the margins of the tumor
Externí odkaz:
https://doaj.org/article/366020fb853f4fc9a179cc6125b7309b
Autor:
Mathilde Bausart, Elia Bozzato, Nicolas Joudiou, Xanthippi Koutsoumpou, Bella Manshian, Véronique Préat, Bernard Gallez
Publikováno v:
Cancers, Vol 15, Iss 6, p 1919 (2023)
Orthotopic glioblastoma xenografts are paramount for evaluating the effect of innovative anti-cancer treatments. In longitudinal studies, tumor growth (or regression) of glioblastoma can only be monitored by noninvasive imaging. For this purpose, bio
Externí odkaz:
https://doaj.org/article/eb09aeb2cb4e4c7db1dfd2938830f092
Autor:
Mahsa Sedighi, Neha Shrestha, Zahra Mahmoudi, Zahra Khademi, Alireza Ghasempour, Hamideh Dehghan, Seyedeh Fahimeh Talebi, Maryam Toolabi, Véronique Préat, Bozhi Chen, Xindong Guo, Mohammad-Ali Shahbazi
Publikováno v:
Polymers, Vol 15, Iss 5, p 1160 (2023)
Self-assembly is a growth mechanism in nature to apply local interactions forming a minimum energy structure. Currently, self-assembled materials are considered for biomedical applications due to their pleasant features, including scalability, versat
Externí odkaz:
https://doaj.org/article/bcd24fbe526f404bb2761e5e3fb6dbaf
Autor:
Alessandra Lopes, Sara Feola, Sophie Ligot, Manlio Fusciello, Gaëlle Vandermeulen, Véronique Préat, Vincenzo Cerullo
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 7, Iss 1, Pp 1-14 (2019)
Abstract Background DNA vaccines against cancer held great promises due to the generation of a specific and long-lasting immune response. However, when used as a single therapy, they are not able to drive the generated immune response into the tumor,
Externí odkaz:
https://doaj.org/article/a691b1b69c484d54a81031648b3101b9
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 38, Iss 1, Pp 1-24 (2019)
Abstract The recent developments in immuno-oncology have opened an unprecedented avenue for the emergence of vaccine strategies. Therapeutic DNA cancer vaccines are now considered a very promising strategy to activate the immune system against cancer
Externí odkaz:
https://doaj.org/article/266643271ceb418fa88d4810e9fd2ada