Zobrazeno 1 - 10
of 70
pro vyhledávání: '"Véronique Mansat‐De MAS"'
Autor:
Charly Courdy, Loïc Platteeuw, Charlotte Ducau, Isabelle De Araujo, Emeline Boet, Ambrine Sahal, Estelle Saland, Valérie Edmond, Suzanne Tavitian, Sarah Bertoli, Pierre Cougoul, Fanny Granat, Laura Poillet, Caroline Marty, Isabelle Plo, Jean-Emmanuel Sarry, Stéphane Manenti, Véronique Mansat-De Mas, Carine Joffre
Publikováno v:
Blood Cancer Journal, Vol 13, Iss 1, Pp 1-10 (2023)
Abstract The Janus kinase 2 (JAK2)-driven myeloproliferative neoplasms (MPNs) are chronic malignancies associated with high-risk complications and suboptimal responses to JAK inhibitors such as ruxolitinib. A better understanding of cellular changes
Externí odkaz:
https://doaj.org/article/f1e0dd6471384291bb94a7aca671d64a
Autor:
François Vergez, Laetitia Largeaud, Sarah Bertoli, Marie-Laure Nicolau, Jean-Baptiste Rieu, Inès Vergnolle, Estelle Saland, Audrey Sarry, Suzanne Tavitian, Françoise Huguet, Muriel Picard, Jean-Philippe Vial, Nicolas Lechevalier, Audrey Bidet, Pierre-Yves Dumas, Arnaud Pigneux, Isabelle Luquet, Véronique Mansat-De Mas, Eric Delabesse, Martin Carroll, Gwenn Danet-Desnoyers, Jean-Emmanuel Sarry, Christian Récher
Publikováno v:
Blood Cancer Journal, Vol 12, Iss 8, Pp 1-11 (2022)
Abstract Classifications of acute myeloid leukemia (AML) patients rely on morphologic, cytogenetic, and molecular features. Here we have established a novel flow cytometry-based immunophenotypic stratification showing that AML blasts are blocked at s
Externí odkaz:
https://doaj.org/article/d9e29c225e7649168cd1370ebb1c8953
Autor:
Claudie Bosc, Nicolas Broin, Marjorie Fanjul, Estelle Saland, Thomas Farge, Charly Courdy, Aurélie Batut, Rawand Masoud, Clément Larrue, Sarah Skuli, Nicolas Espagnolle, Jean-Christophe Pagès, Alice Carrier, Frédéric Bost, Justine Bertrand-Michel, Jérôme Tamburini, Christian Récher, Sarah Bertoli, Véronique Mansat-De Mas, Stéphane Manenti, Jean-Emmanuel Sarry, Carine Joffre
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
How autophagy supports tumor cell metabolism is not fully clear. Here, the authors show that autophagy regulates lipid availability to support mitochondrial oxidative metabolism through mitochondria-endoplasmic reticulum contact sites, necessary for
Externí odkaz:
https://doaj.org/article/8cc02f2742d84833a052afbcc115d3a3
Autor:
Lucie Coster, Véronique Mansat‐De MAS, Laetitia Largeaud, Sophie Voisin, Jill Corre, Martin Gauthier
Publikováno v:
eJHaem, Vol 2, Iss 3, Pp 655-656 (2021)
Externí odkaz:
https://doaj.org/article/7734c9f2de0945c5a5afd5a9b3e8514d
Publikováno v:
Biology, Vol 10, Iss 6, p 552 (2021)
Autophagy, which literally means “eat yourself”, is more than just a lysosomal degradation pathway. It is a well-known regulator of cellular metabolism and a mechanism implicated in tumor initiation/progression and therapeutic resistance in many
Externí odkaz:
https://doaj.org/article/802362d4442f43d5a8ba9742cda3f1d6
Autor:
Karen Delavigne, Emilie Bérard, Sarah Bertoli, Jill Corre, Eliane Duchayne, Cécile Demur, Véronique Mansat-De Mas, Cécile Borel, Muriel Picard, Muriel Alvarez, Audrey Sarry, Françoise Huguet, Christian Récher
Publikováno v:
Haematologica, Vol 99, Iss 3 (2014)
Hemophagocytic lymphohistiocytosis is a condition of immune dysregulation characterized by severe organ damage induced by a hyperinflammatory response and uncontrolled T-cell and macrophage activation. Secondary hemophagocytic lymphohistiocytosis typ
Externí odkaz:
https://doaj.org/article/98a32f47c3f343629294f0358be80ef8
Autor:
Olivier Kosmider, Eric Delabesse, Véronique Mansat-De Mas, Pascale Cornillet-Lefebvre, Odile Blanchet, Alain Delmer, Christian Recher, Sophie Raynaud, Didier Bouscary, Franck Viguié, Catherine Lacombe, Olivier A. Bernard, Norbert Ifrah, François Dreyfus, Michaëla Fontenay
Publikováno v:
Haematologica, Vol 96, Iss 7 (2011)
Ten-eleven translocation 2 (TET2) mutations have been involved in myeloid malignancies. This retrospective study aims at evaluating the frequency and impact of TET2 mutations in 247 secondary acute myeloid leukemia cases referred to as myelodysplasia
Externí odkaz:
https://doaj.org/article/2ad7888a705f47b5ac294e8d78966d3c
Autor:
Alban Canali, Inès Vergnolle, Sarah Bertoli, Laetitia Largeaud, Marie-Laure Nicolau, Jean-Baptiste Rieu, Suzanne Tavitian, Françoise Huguet, Muriel Picard, Pierre Bories, Jean Philippe Vial, Nicolas Lechevalier, Marie Christine Béné, Isabelle Luquet, Véronique Mansat-De Mas, Eric Delabesse, Christian Récher, François Vergez
Publikováno v:
Clinical Cancer Research. 29:134-142
Purpose: Acute myeloid leukemias (AML) are clonal diseases that develop from leukemic stem cells (LSC) that carry an independent prognostic impact on the initial response to induction chemotherapy, demonstrating the clinical relevance of LSC abundanc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cfc2a8887bc7cd6d29a1b8cd9a9f5d19
https://doi.org/10.1158/1078-0432.ccr-22-2237
https://doi.org/10.1158/1078-0432.ccr-22-2237
Autor:
Christian Récher, Jean Emmanuel Sarry, Stéphane Manenti, Jérôme Tamburini, Marie-Anne Hospital, Véronique Mansat-De Mas, Eric Delabesse, Nizar Serhan, François Vergez, Estelle Saland, Clément Larrue
This file contains additional figures that enrich results presented in the main manuscript. We evaluated the impact of the 2-DG on the expression of both wild-type FLT3 and KIT. Then, we excluded a potential role for cellular protein degradation path
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08494bdebd508c623b513fc117300b99
https://doi.org/10.1158/1535-7163.22506504.v1
https://doi.org/10.1158/1535-7163.22506504.v1
Autor:
Christian Récher, Jean Emmanuel Sarry, Stéphane Manenti, Jérôme Tamburini, Marie-Anne Hospital, Véronique Mansat-De Mas, Eric Delabesse, Nizar Serhan, François Vergez, Estelle Saland, Clément Larrue
We assessed the antileukemic activity of 2-deoxy-d-glucose (2-DG) through the modulation of expression of receptor tyrosine kinases (RTK) commonly mutated in acute myeloid leukemia (AML). We used human leukemic cell lines cells, both in vitro and in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::122bb55a61312cad68d5180738cbfea1
https://doi.org/10.1158/1535-7163.c.6538419.v1
https://doi.org/10.1158/1535-7163.c.6538419.v1