Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Véronique Hamon"'
Autor:
Amandine Cartier-Michaud, Anne-Laure Bailly, Stéphane Betzi, Xiaoli Shi, Jean-Claude Lissitzky, Ana Zarubica, Arnauld Sergé, Philippe Roche, Adrien Lugari, Véronique Hamon, Florence Bardin, Carine Derviaux, Frédérique Lembo, Stéphane Audebert, Sylvie Marchetto, Bénédicte Durand, Jean-Paul Borg, Ning Shi, Xavier Morelli, Michel Aurrand-Lions
Publikováno v:
PLoS Genetics, Vol 13, Iss 6, p e1006803 (2017)
Spermatogenesis is a dynamic process that is regulated by adhesive interactions between germ and Sertoli cells. Germ cells express the Junctional Adhesion Molecule-C (JAM-C, encoded by Jam3), which localizes to germ/Sertoli cell contacts. JAM-C is in
Externí odkaz:
https://doaj.org/article/bedb603c57514fa283b9ee3eebe39a42
Autor:
Louis-Marie Bloyet, Joanna Brunel, Marion Dosnon, Véronique Hamon, Jenny Erales, Antoine Gruet, Carine Lazert, Christophe Bignon, Philippe Roche, Sonia Longhi, Denis Gerlier
Publikováno v:
PLoS Pathogens, Vol 12, Iss 12, p e1006058 (2016)
Measles virus (MeV) and all Paramyxoviridae members rely on a complex polymerase machinery to ensure viral transcription and replication. Their polymerase associates the phosphoprotein (P) and the L protein that is endowed with all necessary enzymati
Externí odkaz:
https://doaj.org/article/a1aabcaba6c34ec1b458849c2a92a534
Autor:
Elena De Vita, Niels Smits, Helma van den Hurk, Elizabeth M. Beck, Joanne Hewitt, Gemma Baillie, Emily Russell, Andrew Pannifer, Véronique Hamon, Angus Morrison, Stuart P. McElroy, Philip Jones, Natalia A. Ignatenko, Nikolas Gunkel, Aubry K. Miller
Kallikrein-related peptidase 6 (KLK6) is a secreted serine protease that belongs to the family of tissue kallikreins. Aberrant expression of KLK6 has been found in different cancers and neurodegenerative diseases, and KLK6 is currently studied as a p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::977b4da381966adcd88d776530a8130d
https://doi.org/10.26434/chemrxiv.9788276.v1
https://doi.org/10.26434/chemrxiv.9788276.v1
Autor:
Antoine Gruet, Carine Lazert, Christophe Bignon, Louis Marie Bloyet, Sonia Longhi, Joanna Brunel, Véronique Hamon, Marion Dosnon, Jenny Erales, Philippe Roche, Denis Gerlier
Publikováno v:
PLoS Pathogens
PLoS Pathogens, 2016, 12 (12), pp.e1006058. ⟨10.1371/journal.ppat.1006058⟩
PLoS Pathogens, Public Library of Science, 2016, 12 (12), pp.e1006058. ⟨10.1371/journal.ppat.1006058⟩
PLoS Pathogens, Vol 12, Iss 12, p e1006058 (2016)
PLoS Pathogens, 2016, 12 (12), pp.e1006058. ⟨10.1371/journal.ppat.1006058⟩
PLoS Pathogens, Public Library of Science, 2016, 12 (12), pp.e1006058. ⟨10.1371/journal.ppat.1006058⟩
PLoS Pathogens, Vol 12, Iss 12, p e1006058 (2016)
Measles virus (MeV) and all Paramyxoviridae members rely on a complex polymerase machinery to ensure viral transcription and replication. Their polymerase associates the phosphoprotein (P) and the L protein that is endowed with all necessary enzymati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89143c59dade05a6478f405c9278c38c
https://hal.science/hal-02474235/document
https://hal.science/hal-02474235/document
Autor:
Sébastien Combes, Jean Michel Brunel, Marie Jeanne Basse, Philippe Roche, Xavier Morelli, Véronique Hamon
Publikováno v:
MedChemComm. 4:797-809
We have recently developed a 2P2IHUNTER learning machine tool for filtering potential orthosteric PPI modulators. In the present research article we applied our algorithm to 8.3 million compounds representing the main chemical providers commercially
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::124df921c34fee44de7e821fb4b0a831
https://doi.org/10.1039/c3md00018d
https://doi.org/10.1039/c3md00018d
Autor:
Carine Derviaux, Brigitt Raux, Etienne Rebuffet, Thomas Roux, Eric Trinquet, Cécilia Eydoux, Michel Aurrand-Lions, Marie-Jeanne Basse, Philippe Roche, Stefan Knapp, Stephane Betzi, Jean-Claude Guillemot, Jean-Claude Lissitzky, Sébastien Combes, Audrey Restouin, Xavier Morelli, Pascale Zimmermann, Marion Badol, Marie-Edith Gourdel, Sabine Milhas, Véronique Hamon, Susanne Müller, Adrien Lugari, Yves Collette, Catherine Rogers, Rudra Kashyap
Publikováno v:
ACS Chemical Biology. 11(8)
Protein-protein interactions (PPIs) represent an enormous source of opportunity for therapeutic intervention. We and others have recently pinpointed key rules that will help in identifying the next generation of innovative drugs to tackle this challe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f9f76a7051d319e3863ed8afd303959c
http://ora.ox.ac.uk/objects/uuid:195f078f-0298-4ea2-8d67-8a21b856f859
http://ora.ox.ac.uk/objects/uuid:195f078f-0298-4ea2-8d67-8a21b856f859
Autor:
Marie Jeanne Basse, Bernard Chetrit, Raphaël Bourgeas, Philippe Roche, Stéphane Betzi, Sofia Bouzidi, Xavier Morelli, Véronique Hamon
Publikováno v:
Nucleic Acids Research
Protein–protein interactions are considered as one of the next generation of therapeutic targets. Specific tools thus need to be developed to tackle this challenging chemical space. In an effort to derive some common principles from recent successe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0dd94edc524d1cb460ed492453e2f8b6
https://doi.org/10.1093/nar/gks1002
https://doi.org/10.1093/nar/gks1002
Autor:
Jean Michel Brunel, Pierre Ducrot, Raphaël Bourgeas, Isabelle Theret, Laura Xuereb, Sebastien Combes, Marie Jeanne Basse, Véronique Hamon, Philippe Roche, Xavier Morelli
Publikováno v:
Journal of the Royal Society, Interface. 11(90)
Over the last 10 years, protein–protein interactions (PPIs) have shown increasing potential as new therapeutic targets. As a consequence, PPIs are today the most screened target class in high-throughput screening (HTS). The development of broad che
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb288715fe08b7ea73874da6e437d5cf
https://pubmed.ncbi.nlm.nih.gov/24196694
https://pubmed.ncbi.nlm.nih.gov/24196694
Autor:
Céline Junges, Alban Arrault, Marc Bertrand, Dragos Horvath, Véronique Hamon, Julie Desrivot, Philippe Vayer, Cédric Gaudin
Publikováno v:
Molecular informatics. 31(9)
Drugdrug interaction potential (DDI), especially cytochrome P450 (CYP) 3A4 inhibition potential, is one of the most important parameters to be optimized before preclinical and clinical pharmaceutical development as regard to the number of marketed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3d4520dcd62f6119859df1710236a45
https://pubmed.ncbi.nlm.nih.gov/27477817
https://pubmed.ncbi.nlm.nih.gov/27477817
Autor:
Caroline Aninat, Véronique Hamon, Yoshio Hayashi, Catherine Abadie, Marcel Delaforge, François André, Lionel Perrin, Bruno Heyd
Publikováno v:
Drug Metabolism and Disposition
Drug Metabolism and Disposition, American Society for Pharmacology and Experimental Therapeutics (ASPET), 2008, sous presse
Drug Metabolism and Disposition, 2008, sous presse
HAL
Drug Metabolism and Disposition, American Society for Pharmacology and Experimental Therapeutics (ASPET), 2008, sous presse
Drug Metabolism and Disposition, 2008, sous presse
HAL
Phenylahistin is a fungal diketopiperazine derived from isoprenylated (Phe-DeltaHis) cyclodipeptide. The (-)-enantiomer is a cell cycle inhibitor, which can be potentially used as an antitumor agent. By contrast, the (+)-enantiomer exhibits no antimi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a430900ae66597edf4003500e20f368a
https://hal.archives-ouvertes.fr/hal-00363500
https://hal.archives-ouvertes.fr/hal-00363500