Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Véronique Guénard"'
Autor:
Rudolf Martini, Beat Schweitzer, Véronique Guénard, Eckhard Flechsig, Ueli Suter, Silvio Hemmi, Melitta Schachner
Publikováno v:
Glia. 25:165-178
Mutations in the gene encoding for the myelinating Schwann cell protein P0 have been linked to inherited peripheral neuropathies, including the Charcot-Marie-Tooth type 1B disease (CMT1B) and Dejerine-Sottas syndrome (DSS). Recently generated mice de
Publikováno v:
Spinal Surgery. 12:123-144
Publikováno v:
Glia. 19:247-258
Insulin-like growth factor-I (IGF-I) promotes axonal regeneration in the peripheral nervous system and this effect is enhanced by platelet-derived growth factor (PDGF). We decided, therefore, to study the effects of these factors on axonal regenerati
Publikováno v:
Journal of Neurocytology. 26:1-16
Transplantation of cellular components of the permissive peripheral nerve environment in some types of spinal cord injury holds great promise to support regrowth of axons through the site of injury. In the present study, Schwann cell grafts were posi
Publikováno v:
Glia. 18:27-38
Onion bulb formation is a pathological feature observed in peripheral nerves of patients suffering from inherited peripheral neuropathies such as Charcot-Marie-Tooth and Dejerine-Sottas diseases. An onion bulb consists of small circumferentially orie
Publikováno v:
Experimental Neurology. 137:175-190
Mechanisms inducing gliosis following injury in the central nervous sy stem are poorly understood. We evaluated the effect of axonal injury on astrocyte and Schwann cell proliferation and morphology in vitro. Purified rat dorsal root ganglion neurons
Autor:
Nancy Ratner, Lisa Gwynn, Thorsten Rosenbaum, Thomas Doetschman, Patrick M. Wood, Véronique Guénard
Publikováno v:
Glia. 13:309-318
Mechanisms regulating Schwann cell proliferation during development are unclear. Schwann cell division is known to be driven by an unidentified mitogen present on the surface of axons, but it is not known whether other molecules play a role in regula
Publikováno v:
Journal of Comparative Neurology. 351:145-160
Schwann cells (SC) have been shown to promote regeneration in both the peripheral and central nervous systems. In this study we tested the ability of SC to enhance axonal regeneration in adult rat spinal cord by grafting SC-seeded guidance channels i
Publikováno v:
The Journal of Neuroscience. 15:419-428
Mechanisms regulating Schwann cell differentiation into a myelinating or a mature nonmyelinating phenotype during development are poorly understood. Humoral factors such as members of the transforming growth factor-beta (TGF-beta) family, which are f
Publikováno v:
The Journal of Neuroscience. 14:2980-2992
Schwann cells promote the regrowth of nerve fibers in both the PNS and CNS and might thus be of value in strategies to promote repair following injury or demyelination in the CNS. The effectiveness of Schwann cells in promoting repair could, however,