Zobrazeno 1 - 10
of 51
pro vyhledávání: '"Véronique Freund-Michel"'
Autor:
Guillaume Cardouat, Matthieu Douard, Clément Bouchet, Lukas Roubenne, Zuzana Kmecová, Pauline Esteves, Fabien Brette, Christophe Guignabert, Ly Tu, Marilyne Campagnac, Paul Robillard, Florence Coste, Frédéric Delcambre, Matthieu Thumerel, Hugues Begueret, Arnaud Maurac, Yaniss Belaroussi, Jan Klimas, Thomas Ducret, Jean-François Quignard, Pierre Vacher, Isabelle Baudrimont, Roger Marthan, Patrick Berger, Christelle Guibert, Véronique Freund-Michel
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 174, Iss , Pp 116552- (2024)
Aims: Pulmonary hypertension (PH) is characterised by an increase in pulmonary arterial pressure, ultimately leading to right ventricular failure and death. We have previously shown that nerve growth factor (NGF) plays a critical role in PH. Our obje
Externí odkaz:
https://doaj.org/article/4cca5db9339f4a899b1b390f455c004e
Autor:
Clément Bouchet, Guillaume Cardouat, Matthieu Douard, Florence Coste, Paul Robillard, Frédéric Delcambre, Thomas Ducret, Jean-François Quignard, Pierre Vacher, Isabelle Baudrimont, Roger Marthan, Patrick Berger, Christelle Guibert, Véronique Freund-Michel
Publikováno v:
Cells, Vol 11, Iss 18, p 2795 (2022)
Expression of the nerve growth factor NGF is increased in pulmonary hypertension (PH). We have here studied whether oxidative stress and inflammation, two pathological conditions associated with transforming growth factor-β1 (TGF-β1) in PH, may tri
Externí odkaz:
https://doaj.org/article/73fa479d5bfd4f5b91e2f44b4a843890
Autor:
Solène Barbeau, Alexandre Joushomme, Yann Chappe, Guillaume Cardouat, Isabelle Baudrimont, Véronique Freund-Michel, Christelle Guibert, Roger Marthan, Patrick Berger, Pierre Vacher, Yann Percherancier, Jean-François Quignard, Thomas Ducret
Publikováno v:
Biomolecules, Vol 12, Iss 7, p 954 (2022)
Transient receptor potential vanilloid 4 (TRPV4) is a polymodal Ca2+-permeable channel involved in various hypoxia-sensitive pathophysiological phenomena. Different tools are available to study channel activity, requiring cells to be cultured at spec
Externí odkaz:
https://doaj.org/article/a5dbf282674240718c056e11d5ad242f
Autor:
Thais Porto Ribeiro, Solène Barbeau, Isabelle Baudrimont, Pierre Vacher, Véronique Freund-Michel, Guillaume Cardouat, Patrick Berger, Christelle Guibert, Thomas Ducret, Jean-François Quignard
Publikováno v:
Cells, Vol 11, Iss 15, p 2349 (2022)
In intrapulmonary arteries (IPAs), mechanical forces due to blood flow control vessel tone, and these forces change during pulmonary hypertension (PH). Piezo1, a stretch-activated calcium channel, is a sensor of mechanical stress present in both endo
Externí odkaz:
https://doaj.org/article/b367f11548ab4bd4ad54b29a33085af3
Autor:
Ophélie Germande, Thomas Ducret, Jean-Francois Quignard, Juliette Deweirdt, Véronique Freund-Michel, Marie-Hélène Errera, Guillaume Cardouat, Pierre Vacher, Bernard Muller, Patrick Berger, Christelle Guibert, Magalie Baudrimont, Isabelle Baudrimont
Publikováno v:
Antioxidants, Vol 11, Iss 5, p 847 (2022)
The development and use of nanomaterials, especially of nickel oxide nanoparticles (NiONPs), is expected to provide many benefits but also has raised concerns about the potential human health risks. Inhaled NPs are known to exert deleterious cardiova
Externí odkaz:
https://doaj.org/article/45ef2046b1994d81bee875471a451016
Autor:
Solène Barbeau, Guillaume Gilbert, Guillaume Cardouat, Isabelle Baudrimont, Véronique Freund-Michel, Christelle Guibert, Roger Marthan, Pierre Vacher, Jean-François Quignard, Thomas Ducret
Publikováno v:
Biomolecules, Vol 11, Iss 9, p 1389 (2021)
A variety of cell types in pulmonary arteries (endothelial cells, fibroblasts, and smooth muscle cells) are continuously exposed to mechanical stimulations such as shear stress and pulsatile blood pressure, which are altered under conditions of pulmo
Externí odkaz:
https://doaj.org/article/2c4e660cd3b145d48dd877775be60acc
Autor:
Eric Dumas de la Roque, Gwladys Smeralda, Jean-François Quignard, Véronique Freund-Michel, Arnaud Courtois, Roger Marthan, Bernard Muller, Christelle Guibert, Mathilde Dubois
Publikováno v:
PLoS ONE, Vol 12, Iss 2, p e0173044 (2017)
Bronchopulmonary dysplasia (BPD) consists of an arrest of pulmonary vascular and alveolar growth, with persistent hypoplasia of the pulmonary microvasculature and alveolar simplification. In 25 to 40% of the cases, BPD is complicated by pulmonary hyp
Externí odkaz:
https://doaj.org/article/8d3a453ea9434beb99c745b79dbcb5c5
Autor:
Véronique Freund-Michel, Christelle Guibert, Mathilde Dubois, Arnaud Courtois, Roger Marthan, Jean-Pierre Savineau, Bernard Muller
Publikováno v:
Therapeutic Advances in Respiratory Disease, Vol 7 (2013)
Pulmonary hypertension (PH) is characterized by a progressive elevation of pulmonary arterial pressure due to alterations of both pulmonary vascular structure and function. This disease is rare but life-threatening, leading to the development of righ
Externí odkaz:
https://doaj.org/article/6f29c672da004472ae96316c3e4485eb
Autor:
Mathilde Dubois, Estelle Delannoy, Lucie Duluc, Ellen Closs, Huige Li, Christian Toussaint, Alain-Pierre Gadeau, Axel Gödecke, Véronique Freund-Michel, Arnaud Courtois, Roger Marthan, Jean-Pierre Savineau, Bernard Muller
Publikováno v:
PLoS ONE, Vol 8, Iss 11, p e82594 (2013)
Tetrahydrobiopterin (BH4), which fosters the formation of and stabilizes endothelial NO synthase (eNOS) as an active dimer, tightly regulates eNOS coupling / uncoupling. Moreover, studies conducted in genetically-modified models demonstrate that BH4
Externí odkaz:
https://doaj.org/article/daf2ff7938b441cca853d75689a580ad
Autor:
Isabelle Dupin, Pauline Henrot, Elise Maurat, Reshed Abohalaka, Sébastien Chaigne, Dounia El Hamrani, Edmée Eyraud, Renaud Prevel, Pauline Esteves, Maryline Campagnac, Marielle Dubreuil, Guillaume Cardouat, Clément Bouchet, Olga Ousova, Jean-William Dupuy, Thomas Trian, Matthieu Thumerel, Hugues Bégueret, Pierre-Olivier Girodet, Roger Marthan, Maeva Zysman, Véronique Freund-Michel, Patrick Berger
RationaleChronic obstructive pulmonary disease (COPD) is a prevalent respiratory disease lacking effective treatment. Focusing on the early stage of COPD should help to discover disease modifying therapies.ObjectivesIn this study, we examined the rol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::80322ef4585cb0511f643efb0c6a52e5
https://doi.org/10.1101/2023.03.10.529743
https://doi.org/10.1101/2023.03.10.529743