Oleic acid stimulation of amino acid uptake in primary human trophoblast cells is mediated by phosphatidic acid and mTOR signaling

Autor: Elena Silva, Véronique Ferchaud‐Roucher, Anita Kramer, Lana Madi, Priyadarshini Pantham, Stephanie Chassen, Thomas Jansson, Theresa L. Powell

Publikováno v: FASEB BioAdvances, Vol 6, Iss 1, Pp 1-11 (2024)

Abstract Normal fetal development is critically dependent on optimal nutrient supply by the placenta, and placental amino acid transport has been demonstrated to be positively associated with fetal growth. Mechanistic target of rapamycin (mTOR) is a

Externí odkaz: https://doaj.org/article/6adb0c403a7a455989befc49335ab12d

Multiplexed peptide analysis for kinetic measurements of major human apolipoproteins by LC/MS/MS[S]

Autor: Mikaël Croyal, Fanta Fall, Véronique Ferchaud-Roucher, Maud Chétiveaux, Yassine Zaïr, Khadija Ouguerram, Michel Krempf, Estelle Nobécourt

Publikováno v: Journal of Lipid Research, Vol 57, Iss 3, Pp 509-515 (2016)

A multiplexed assay was developed by MS to analyze, in a single run, six major human Apos involved in lipoprotein metabolism: ApoA-I, ApoA-II, ApoB100, ApoC-II, ApoC-III, and ApoE. This method was validated in vivo in six subjects who received a 14 h

Externí odkaz: https://doaj.org/article/fd2b6b896449462c8e5b1d28b8c85482

Omega 3 Improves Both apoB100-containing Lipoprotein Turnover and their Sphingolipid Profile in Hypertriglyceridemia

Autor: Véronique Ferchaud-Roucher, Yassine Zair, Michel Krempf, Khadija Ouguerram, Audrey Aguesse

Publikováno v: Journal of Clinical Endocrinology and Metabolism
Journal of Clinical Endocrinology and Metabolism, Endocrine Society, 2020, 105 (10), pp.3152-3164. ⟨10.1210/clinem/dgaa459⟩

Context Evidence for an association between sphingolipids and metabolic disorders is increasingly reported. Omega-3 long-chain polyunsaturated fatty acids (n-3 LC-PUFAs) improve apolipoprotein B100 (apoB100)-containing lipoprotein metabolism, but the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd19f12d0f59bfbe1ffa404f16460979
https://doi.org/10.1210/clinem/dgaa459

Maternal obesity leads to long-term altered levels of plasma ceramides in the offspring as revealed by a longitudinal lipidomic study in children

Autor: Francisco Bolaños-Jiménez, Fengyang Huang, Michel Krempf, Laurence A. Marchat, Mikaël Croyal, Isabelle Romieu, Véronique Ferchaud-Roucher, Khadija Ouguerram, Rosalio Mercado-Camargo, Albino Barraza-Villarreal, Luis Felipe León-Aguilar, Usha Ramakrishnan

Publikováno v: International Journal of Obesity
International Journal of Obesity, Nature Publishing Group, 2019, 43 (6), pp.1231-1243. ⟨10.1038/s41366-018-0291-y⟩

International audience; Background/objectives Maternal obesity is associated with increased risk of obesity and other symptoms of the metabolic syndrome in the offspring. Nevertheless, the molecular mechanisms and cellular factors underlying this enh

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d897e8e5ee92da385bc5ca066d12d32
https://hal.archives-ouvertes.fr/hal-02429513/document

Consequences of blunting the mevalonate pathway in cancer identified by a pluriomics approach

Autor: Julie Lalande, Véronique Ferchaud-Roucher, Mikaël Croyal, Alain Bouchereau, Sophie Goulitquer, Catherine Le Jossic-Corcos, Jean-Philippe Antignac, Serge Akoka, Michel Krempf, Stéphanie Durand, Yann Guitton, Philippe Potin, Danielle Arzur, Patrick Giraudeau, Anne-Lise Royer, Laurent Corcos

Publikováno v: Cell Death and Disease
Cell Death and Disease, Nature Publishing Group, 2018, 9 (7), pp.745. ⟨10.1038/s41419-018-0761-0⟩
Cell Death and Disease, Nature Publishing Group, 2018, 9 (7), ⟨10.1038/s41419-018-0761-0⟩
Cell Death and Disease, 2018, 9 (7), pp.745. ⟨10.1038/s41419-018-0761-0⟩
Cell Death & Disease
Cell Death and Disease 7 (9), 745. (2018)
Cell Death and Disease, Vol 9, Iss 7, Pp 1-12 (2018)

We have previously shown that the combination of statins and taxanes was a powerful trigger of HGT-1 human gastric cancer cells’ apoptosis1. Importantly, several genes involved in the “Central carbon metabolism pathway in cancer”, as reported i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73b873a4ea4ccd1d73e2775b2d84e488
https://hal.archives-ouvertes.fr/hal-02140936/document