Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Véronique Charrier"'
Autor:
Jean Pierre Marquette, Andreas Karlsson, Sylvie Monget, Thomas Bertrand, Jean Christophe Carry, Frank Halley, Marc Antoine Perrin, Jean Paul Nicolas, Tsiala Benard, Angela Virone-Oddos, Luc Bertin, Céline Amara, Hélène Bonnevaux, Laurence Delbarre, Gilles Doerflinger, Pierre Yves Abecassis, Youssef El-Ahmad, Véronique Charrier, Victor Certal, Bruno Filoche-Romme, Florence Gruss-Leleu, Sébastien Perron, Alexey Rak, Patrick Richepin, Stephane Guerif, Carlos Garcia-Echeverria, Loic Vincent, Nadine Michot, Magali Mathieu, Véronique Loyau, Olivier Lemaitre, Maurice Brollo, Christoph Lengauer, Houlfa Guizani, Laurent Schio, Fabienne Thompson, Cécile Delorme
Publikováno v:
Journal of Medicinal Chemistry. 57:903-920
Compelling molecular biology publications have reported the implication of phosphoinositide kinase PI3Kβ in PTEN-deficient cell line growth and proliferation. These findings supported a scientific rationale for the development of PI3Kβ-specific inh
Autor:
Christoph Lengauer, Pierre Yves Abecassis, Luc Bertin, Véronique Charrier, Laurent Schio, Jean Christophe Carry, Patrick Richepin, Loic Vincent, Bruno Filoche-Romme, Florence Gruss-Leleu, Houlfa Guizani, Carlos Garcia-Echeverria, Angela Virone-Oddos, Andreas Karlsson, Jean Paul Nicolas, Victor Certal, Fabienne Pilorge, Frank Halley
Publikováno v:
Bioorganicmedicinal chemistry letters. 24(6)
In our continuous efforts to identify and develop novel targeted cancer treatments, a new morpholino-thiazole scaffold active against PI3Kβ has been identified. This Letter reports the optimization of this compound class to develop PI3Kβ isoform-se
Autor:
Florence Fassy, Yvette Taburet, Caroline Peneff, V. Zamboni, Jacques Winter, Paul Ferrari, Véronique Charrier, Marzia Harnois, Yves Bourne, Célia Monnier
Publikováno v:
The EMBO Journal. 20:6191-6202
The recently published human genome with its relatively modest number of genes has highlighted the importance of post-transcriptional and post-translational modifications, such as alternative splicing or glycosylation, in generating the complexities
Publikováno v:
Biochemistry. 39:5035-5044
As reported previously [Parsonage, D., Luba, J., Mallett, T. C., and Claiborne, A. (1998) J. Biol. Chem. 273, 23812-23822], the flavoprotein alpha-glycerophosphate oxidases (GlpOs) from a number of enterococcal and streptococcal sources contain a con
Publikováno v:
Biochemistry. 38:2725-2737
An unusual flavoprotein disulfide reductase, which catalyzes the NADPH-dependent reduction of CoASSCoA, has recently been purified from the human pathogen Staphylococcus aureus [delCardayré, S. B., Stock, K. P., Newton, G. L., Fahey, R. C., and Davi
Autor:
Frédéric Bibeau, Vaios Karanikas, M. Pedot, François Quenet, Michael A. Cannarile, Solange Romagnoli, Marc Ychou, Hugo Gil, Florence Boissière-Michot, Véronique Charrier, Florence Castan, Fabien Gaire
Publikováno v:
Journal of Clinical Oncology. 32:3631-3631
3631 Background: An adaptive CD8+/CD45+ immune response, is considered as a favorable prognostic factor in primary colorectal cancer (CRC). FoxP3+regulatory T lymphocytes (Ly) inhibit this response...
Publikováno v:
Acta crystallographica. Section D, Biological crystallography. 58(Pt 1)
Single crystals of soluble FAD-dependent alpha-glycerophosphate oxidase (GlpO) from Streptococcus sp. were obtained using the microseeding and hanging-drop vapor-equilibrium methods. Synchrotron X-ray radiation was used to collect diffraction data to
Autor:
Anne Galinier, Josef Deutscher, Georges Rapoport, Jacques Haiech, Marie-Claude Kilhoffer, Yves Quentin, Emmanuelle Darbon, Véronique Charrier, Isabelle Martin-Verstraete
Publikováno v:
Microbiology
Microbiology, Microbiology Society, 1999, 145 (11), pp.3195-3204. ⟨10.1099/00221287-145-11-3195⟩
Microbiology, Microbiology Society, 1999, 145, pp.3195-3204
Microbiology, Microbiology Society, 1999, 145 (11), pp.3195-3204. ⟨10.1099/00221287-145-11-3195⟩
Microbiology, Microbiology Society, 1999, 145, pp.3195-3204
Crh of Bacillus subtilis exhibits 45% sequence identity when compared to histidine-containing protein (HPr), a phosphocarrier protein of the phosphoenolpyruvate (PEP):sugar phosphotransferase system (PTS). Crh can be phosphorylated by ATP at the regu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90a955eea529ab4f5e759e676b9e9bb3
https://hal.archives-ouvertes.fr/hal-02345022
https://hal.archives-ouvertes.fr/hal-02345022
Autor:
Bernhard Erni, Josef Deutscher, Véronique Charrier, Isabelle Martin-Verstraete, Georges Rapoport, Anne Galinier, Jörg Stülke
Publikováno v:
Molecular Microbiology
Molecular Microbiology, 1998, 28 (2), pp.293-303. ⟨10.1046/j.1365-2958.1998.00781.x⟩
Molecular Microbiology, Wiley, 1998, 28 (2), pp.293-303. ⟨10.1046/j.1365-2958.1998.00781.x⟩
Molecular Microbiology, 1998, 28 (2), pp.293-303. ⟨10.1046/j.1365-2958.1998.00781.x⟩
Molecular Microbiology, Wiley, 1998, 28 (2), pp.293-303. ⟨10.1046/j.1365-2958.1998.00781.x⟩
International audience; LevR, which controls the expression of the lev operon of Bacillus subtilis, is a regulatory protein containing an N‐terminal domain similar to the NifA/NtrC transcriptional activator family and a C‐terminal domain similar
Autor:
Josef Deutscher, Emmanuelle Darbon, Al Claiborne, Véronique Charrier, Derek Parsonage, Anne Galinier, Michel Jaquinod, Eric Forest, Ellen Buckley
Publikováno v:
Journal of Biological Chemistry
Journal of Biological Chemistry, 1997, 272 (22), pp.14166-14174. ⟨10.1074/jbc.272.22.14166⟩
Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, 1997, 272 (22), pp.14166-14174. ⟨10.1074/jbc.272.22.14166⟩
Journal of Biological Chemistry, 1997, 272 (22), pp.14166-14174. ⟨10.1074/jbc.272.22.14166⟩
Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, 1997, 272 (22), pp.14166-14174. ⟨10.1074/jbc.272.22.14166⟩
The glpK genes of Enterococcus casseliflavus and Enterococcus faecalis, encoding glycerol kinase, the key enzyme of glycerol uptake and metabolism in bacteria, have been cloned and sequenced. The translated amino acid sequences exhibit strong homolog