Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Véronique Bourgarel"'
Autor:
Maïlys Rossi, Julie Talbot, Patricia Piris, Marion Le Grand, Marie-Pierre Montero, Mélanie Matteudi, Emilie Agavnian-Couquiaud, Romain Appay, Céline Keime, Daniel Williamson, Duje Buric, Véronique Bourgarel, Laetitia Padovani, Steven C. Clifford, Olivier Ayrault, Eddy Pasquier, Nicolas André, Manon Carré
Publikováno v:
EBioMedicine, Vol 82, Iss , Pp 104149- (2022)
Summary: Background: Medulloblastoma is the most frequent brain malignancy of childhood. The current multimodal treatment comes at the expense of serious and often long-lasting side effects. Drug repurposing is a strategy to fast-track anti-cancer th
Externí odkaz:
https://doaj.org/article/a499363799bd479cbe36ba96452d1e11
Autor:
Amandine Savry, Manon Carre, Raphael Berges, Amandine Rovini, Isabelle Pobel, Christine Chacon, Diane Braguer, Véronique Bourgarel-Rey
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 15, Iss 1, Pp 49-60 (2013)
Bcl-2 is commonly overexpressed in tumors, where it is often associated with unfavorable outcome. However, it has also been linked to a favorable sensitivity to microtubule-targeting agents (MTAs). We show that Bcl-2– overexpressing lung and breast
Externí odkaz:
https://doaj.org/article/6afa7a48fb074511bf561ba859ff26c3
Autor:
Diane Braguer, Anna Kruczynski, Karine Civiletti, Pascal Verdier-Pinard, Véronique Bourgarel-Rey, Géraldine Gauthier, Alessandra Pagano, Stéphane Honoré
The motile behavior of endothelial cells is a crucial event for neoangiogenesis. We previously showed that noncytotoxic concentrations of vinflunine inhibit capillary-like tube formation on Matrigel and endothelial cell migration with a concomitant i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b1f8b9694d3d3003685b712103a7b60
https://doi.org/10.1158/1535-7163.c.6532076.v1
https://doi.org/10.1158/1535-7163.c.6532076.v1
Autor:
Diane Braguer, Anna Kruczynski, Karine Civiletti, Pascal Verdier-Pinard, Véronique Bourgarel-Rey, Géraldine Gauthier, Alessandra Pagano, Stéphane Honoré
Supplementary Fig. S1 from Antiangiogenic vinflunine affects EB1 localization and microtubule targeting to adhesion sites
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::859337f334ed3e66a4fbdb8fdcfd0006
https://doi.org/10.1158/1535-7163.22485785.v1
https://doi.org/10.1158/1535-7163.22485785.v1
Autor:
Diane Braguer, Claudette Briand, Anna Kruczynski, Véronique Bourgarel-Rey, Eddy Pasquier, Stéphane Honoré, Bertrand Pourroy
Angiogenesis is a key event in tumor progression and metastasis. This complex process, which constitutes a potent target for cancer therapy, is inhibited by very low concentrations of microtubule-targeting drugs (MTD). However, the intimate mechanism
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::280baf1da778a50d3971ec5ba4722b53
https://doi.org/10.1158/0008-5472.c.6494802.v1
https://doi.org/10.1158/0008-5472.c.6494802.v1
Autor:
Diane Braguer, Claudette Briand, Anna Kruczynski, Véronique Bourgarel-Rey, Eddy Pasquier, Stéphane Honoré, Bertrand Pourroy
Supplementary Figure 1 from Antiangiogenic Concentrations of Vinflunine Increase the Interphase Microtubule Dynamics and Decrease the Motility of Endothelial Cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d925f720054ba147caccaaf0dc5236b
https://doi.org/10.1158/0008-5472.22365651.v1
https://doi.org/10.1158/0008-5472.22365651.v1
Autor:
Diane Braguer, Véronique Bourgarel-Rey, Manon Carré, Amandine Savry, Raphael Berges, Christine Chacon, Amandine Rovini, Isabelle Pobel
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 15, Iss 1, Pp 49-60 (2013)
Bcl-2 is commonly overexpressed in tumors, where it is often associated with unfavorable outcome. However, it has also been linked to a favorable sensitivity to microtubule-targeting agents (MTAs). We show that Bcl-2– overexpressing lung and breast
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0987753b45e848050256b17c60bdad3
http://www.sciencedirect.com/science/article/pii/S147655861380125X
http://www.sciencedirect.com/science/article/pii/S147655861380125X
Autor:
Véronique Bourgarel-Rey, Nicolas Simon, Bruno Lacarelle, Caroline Solas, Romain Guilhaumou, Angélique Rome, Sylvie Quaranta, Nicolas André
Publikováno v:
Cancer Chemotherapy and Pharmacology. 68:1633-1638
The aim of this study was to investigate the impact of plasma and intracellular exposure and CYP3A4, CYP3A5, and ABCB1 polymorphisms on vincristine neurotoxicity. We subsequently assessed the impact of ABCB1 polymorphisms on intracellular vincristine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7cfeee15a304b7e0d030fc35886d696
https://doi.org/10.1007/s00280-011-1745-2
https://doi.org/10.1007/s00280-011-1745-2
Autor:
Alexey Yu. Fedorov, Véronique Bourgarel-Rey, Jean Boutonnat, Vincent Peyrot, Soazig Douillard, Pascale Barbier, Jean-Pierre Finet, Anne McLeer-Florin, Sebastien Combes, Jean-Thomas Pierson
Publikováno v:
Journal of Medicinal Chemistry. 54:3153-3162
A series of A-ring variously methoxylated 4-(3-hydroxy-4-methoxyphenyl)coumarins related to combretastatin A-4 was prepared by cross-coupling reactions. Cytotoxicity studies indicated a potent activity against HBL100 cell line. Substitution patterns
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9937df9e506a07575eb53e824c0ef4d
https://doi.org/10.1021/jm901826e
https://doi.org/10.1021/jm901826e
Autor:
Jean Imbert, Céline Bressin, Diane Braguer, Amandine Savry, Véronique Bourgarel-Rey, Christine Chacon, Yves Barra, Guoqiang Hua, Manon Carré
Publikováno v:
Biochemical Pharmacology
Biochemical Pharmacology, Elsevier, 2009, 78 (9), pp.1148. ⟨10.1016/j.bcp.2009.06.025⟩
Biochemical Pharmacology, Elsevier, 2009, 78 (9), pp.1148. ⟨10.1016/j.bcp.2009.06.025⟩
International audience; The Bcl-2 family contains a panel of proteins which are conserved regulators of apoptosis in mammalian cells, like the anti-apoptotic protein Bcl-2. According to its significant role in altering susceptibility to apoptosis, th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45edec32d3bb584a408887ca567191a1
https://doi.org/10.1016/j.bcp.2009.06.025
https://doi.org/10.1016/j.bcp.2009.06.025