A catalog of numerical centrosome defects in epithelial ovarian cancers

Autor: Jean‐Philippe Morretton, Anthony Simon, Aurélie Herbette, Jorge Barbazan, Carlos Pérez‐González, Camille Cosson, Bassirou Mboup, Aurélien Latouche, Tatiana Popova, Yann Kieffer, Anne‐Sophie Macé, Pierre Gestraud, Guillaume Bataillon, Véronique Becette, Didier Meseure, André Nicolas, Odette Mariani, Anne Vincent‐Salomon, Marc‐Henri Stern, Fatima Mechta‐Grigoriou, Sergio Roman Roman, Danijela Matic Vignjevic, Roman Rouzier, Xavier Sastre‐Garau, Oumou Goundiam, Renata Basto

Publikováno v: EMBO Molecular Medicine, Vol 14, Iss 9, Pp 1-12 (2022)

Abstract Centrosome amplification, the presence of more than two centrosomes in a cell is a common feature of most human cancer cell lines. However, little is known about centrosome numbers in human cancers and whether amplification or other numerica

Externí odkaz: https://doaj.org/article/b73a9d37289b4069bb8cbf23019a31b3

APCgermline pathogenic variants and epithelial ovarian cancer: causal or coincidental findings?

Autor: Roseline Vibert, Jessica Le Gall, Bruno Buecher, Emmanuelle Mouret-Fourme, Guillaume Bataillon, Véronique Becette, Olfa Trabelsi-Grati, Virginie Moncoutier, Catherine Dehainault, Jennifer Carriere, Mathias Schwartz, Voreak Suybeng, Ivan Bieche, Chrystelle Colas, Anne Vincent-Salomon, Dominique Stoppa-Lyonnet, Lisa Golmard

Publikováno v: Journal of Medical Genetics. 60:460-463

APCgermline pathogenic variants result in predisposition to familial adenomatous polyposis and extraintestinal tumours such as desmoid fibromatosis, medulloblastomas and thyroid cancers. They have also been recently involved in ovarian microcystic st

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d21c76f975e9ed02a26800b75dc505e0
https://doi.org/10.1136/jmg-2022-108467

Co-occurrence of germline BRCA1 and CDH1 pathogenic variants

Autor: Dominique Lamarque, Lisa Golmard, Gilles Marx, Emmanuelle Mouret-Fourme, Marie-Charlotte Villy, Etienne Rouleau, Dominique Stoppa-Lyonnet, Nasrine Callet, Véronique Becette, Chrystelle Colas

Publikováno v: Journal of Medical Genetics. 58:357-361

Introduction: We report a very rare case of familial breast cancer and diffuse gastric cancer, with germline pathogenic variants in both BRCA1 and CDH1 genes. To the best of our knowledge, this is the first report of such an association.Family descri

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e6d877a713cb6d0b77acbec70c3d20ab
https://doi.org/10.1136/jmedgenet-2020-106972

Mise à jour 2021 des recommandations du GEFPICS pour l’évaluation du statut HER2 dans les cancers infiltrants du sein en France

Autor: Bruno Poulet, Alexander Valent, Jean-Pierre Ghnassia, Gaëtan MacGrogan, Lounes Djerroudi, Véronique Becette, Aurélie Maran-Gonzalez, Emmanuelle Charafe-Jauffret, Olivia Abramovici, Marie-Mélanie Dauplat, Cécile Blanc-Fournier, Yves Marie Robin, Agnès Leroux, Isabelle Treilleux, Frédérique Penault-Llorca, Elisabeth Russ, Paul Delrée, Eva Brabencova, Magali Lacroix-Triki, Pascal Roger, Juliette Haudebourg, Martine Antoine, Anca Berghian, Véronique Verriele, Patrick Michenet, Raphaëlle Duprez-Paumier, Marie-Pierre Chenard, Clémence Fleury, Anne Vincent-Salomon, Camille Franchet, Laurent Arnould, Lucie Tixier, Pour le Gefpics, Marie-Christine Mathieu

Publikováno v: Annales de Pathologie
Annales de Pathologie, Elsevier Masson, 2021, ⟨10.1016/j.annpat.2021.07.014⟩

The last international guidelines on HER2 determination in breast cancer have been updated in 2018 by the American Society of Clinical Oncology and College of American Pathologists, on the basis of a twenty-year practice and results of numerous clini

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::292f83395888c73d5447eb356730dcd1
https://hal.archives-ouvertes.fr/hal-03333764

Molecular apocrine tumours in EORTC 10994/BIG 1-00 phase III study: pathological response after neoadjuvant chemotherapy and clinical outcomes

Autor: Richard Iggo, Jean-Michel Picquenot, Denis Larsimont, Véronique Becette, Jonas Bergh, Gaëtan MacGrogan, Jeremy Thomas, Olivier Kerdraon, Leen Slaets, David Cameron, Fanny Pommeret, C. Poncet, Jean-Christophe Tille, Frédéric Bibeau, Hervé Bonnefoi, Alexandre Bodmer, Jean-Pierre Ghnassia, Thomas Grellety

Publikováno v: British Journal of Cancer
British Journal of Cancer, Cancer Research UK, 2019, 120 (9), pp.913-921. ⟨10.1038/s41416-019-0420-y⟩
Bonnefoi, H, MacGrogan, G, Poncet, C, Iggo, R, Pommeret, F, Grellety, T, Larsimont, D, Becette, V, Kerdraon, O, Bibeau, F, Ghnassia, J-P, Picquenot, J-M, Thomas, J, Tille, J-C, Slaets, L, Bodmer, A, Bergh, J & Cameron, D 2019, ' Molecular apocrine tumours in EORTC 10994/BIG 1-00 phase III study: pathological response after neoadjuvant chemotherapy and clinical outcomes ', British Journal of Cancer . https://doi.org/10.1038/s41416-019-0420-y
British Journal of Cancer, 120 (9
British Journal of Cancer, Vol. 120, No 9 (2019) pp. 913-921

Background: We explored, within the EORTC10994 study, the outcomes for patients with molecular apocrine (MA) breast cancer, and defined immunohistochemistry (IHC) as androgen-receptor (AR) positive, oestrogen (ER) and progesterone (PR) negative. We a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8075ed5bffb4cfbba37e33a4360db84c
https://doi.org/10.1038/s41416-019-0420-y