Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Véronique Leçon-Malas"'
Autor:
Delphine Goven, Anne Boutten, Véronique Leçon-Malas, Joëlle Marchal-Sommé, Paul Soler, Jorge Boczkowski, Marcel Bonay
Publikováno v:
PLoS ONE, Vol 5, Iss 5, p e10886 (2010)
Few data concern the pathophysiology of primary spontaneous pneumothorax (PSP), which is associated with alveolar hypoxia/reoxygenation. This study tested the hypothesis that PSP is associated with oxidative stress in lung macrophages. We analysed ex
Externí odkaz:
https://doaj.org/article/fae0e980997f4041866d20ad3b3e62b8
Publikováno v:
FEBS Letters. 583:3508-3518
Tobacco may be involved in the decreased macrophage heme oxygenase-1 (HO-1) expression described in smoking-induced severe emphysema, via the nuclear factor erythroid 2-related factor 2 (Nrf2)/Kelch-like ECH-associated protein 1 (Keap1)–BTB and CNC
Autor:
Joëlle Marchal-Somme, Jorge Boczkowski, Delphine Goven, Paul Soler, Marcel Bonay, Bruno Crestani, Michel Fournier, Véronique Leçon-Malas, Nadia Amara, Guy Lesèche, Anne Boutten
Publikováno v:
Thorax. 63:916-924
Background: Oxidative stress, resulting from the increased oxidative burden and decreased level of antioxidant proteins, plays a role in the pathophysiology of smoking-related pulmonary emphysema. Expression of several antioxidant proteins, such as h
Autor:
Anne Boutten, Sylvain Marchand-Adam, Geneviève Durand, Bruno Crestani, Joëlle Marchal-Somme, Véronique Leçon-Malas, Monique Dehoux, Murielle Cohen
Publikováno v:
American Journal of Physiology-Lung Cellular and Molecular Physiology. 290:L1097-L1103
Oncostatin M (OSM) is a IL-6 family cytokine locally produced in acute lung injury. Its profibrotic properties suggest a role in lung wound repair. Hepatocyte growth factor (HGF), produced by fibroblasts, is involved in pulmonary epithelial repair. W
Changes in airway inflammation following nasal allergic challenge in patients with seasonal rhinitis
Autor:
Michel Aubier, Marcel Bonay, Véronique Leçon-Malas, Martine Grandsaigne, Philippe Ravaud, Monique Dehoux, Catherine Neukirch
Publikováno v:
Allergy. 61:111-118
Background: Seasonal allergic rhinitis could predispose to the development of chronic bronchial inflammation as observed in asthma. However, direct links between nasal inflammation, bronchial inflammation and airway responsiveness in patients with se
Autor:
Véronique Leçon-Malas, Corinne Rolland, Monique Dehoux, Michel Aubier, Jean-Marie Desmonts, Olivier Giraud, Serge Molliex
Publikováno v:
Anesthesiology. 98:74-81
Background Alveolar epithelial type II (AT II ) cells participate in the intraalveolar cytokine network by secreting cytokines and are widely exposed to volatile anesthetics during general anesthesia. The aim of the current study was to evaluate the
Autor:
Anne Boutten, Delphine Goven, Marcel Bonay, Joëlle Marchal-Somme, Paul Soler, Jorge Boczkowski, Véronique Leçon-Malas
Publikováno v:
PLoS ONE
PLoS ONE, Public Library of Science, 2010, 5 (5), pp.e10886. ⟨10.1371/journal.pone.0010886⟩
PLoS ONE, Vol 5, Iss 5, p e10886 (2010)
PLoS ONE, Public Library of Science, 2010, 5 (5), pp.e10886. ⟨10.1371/journal.pone.0010886⟩
PLoS ONE, Vol 5, Iss 5, p e10886 (2010)
International audience; BACKGROUND: Few data concern the pathophysiology of primary spontaneous pneumothorax (PSP), which is associated with alveolar hypoxia/reoxygenation. This study tested the hypothesis that PSP is associated with oxidative stress
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9033ce53c3421578816dcb9932718dcb
https://www.hal.inserm.fr/inserm-00496815
https://www.hal.inserm.fr/inserm-00496815
Autor:
Véronique Leçon-Malas, Michel Aubier, Lyes Tabet, Rafik Bachoual, Delphine Goven, Jorge Boczkowski, Sophie Lanone, Dinhill On, Nadia Amara
Publikováno v:
Chemical research in toxicology. 20(10)
Particulate matter (PM) from atmospheric pollution can easily deposit in the lungs and induce recruitment of inflammatory cells, a source of inflammatory cytokines, oxidants, and matrix metalloproteases (MMPs), which are important players in lung str
Autor:
Michel Fournier, Bruno Crestani, Paul Soler, Guy Lesèche, Monique Dehoux, Anne Boutten, Marcel Bonay, Joëlle Marchal, Véronique Leçon-Malas
Publikováno v:
BMC Pulmonary Medicine, Vol 5, Iss 1, p 13 (2005)
BMC Pulmonary Medicine
BMC Pulmonary Medicine
Background Hepatocyte and keratinocyte growth factors are key growth factors in the process of alveolar repair. We hypothesized that excessive alveolar destruction observed in lung emphysema involves impaired expression of hepatocyte and keratinocyte
Autor:
Bruno Crestani, Véronique Leçon-Malas, G Durand, Michel Fournier, Michel Aubier, Anne Boutten, S Laribe, Monique Dehoux, Marcel Bonay, Guy Lesèche, Y Castier
Publikováno v:
Thorax. 59(10)
Background: The overexpression of interferon (IFN)γ or interleukin (IL)-13 in the adult murine lung induces the development of changes that mirror human lung emphysema. Methods: IL-13 and IFNγ expression was determined in lung samples from five gro