Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Véronique, Lisi"'
Autor:
Damien Maggiorani, Oanh Le, Véronique Lisi, Séverine Landais, Gaël Moquin-Beaudry, Vincent Philippe Lavallée, Hélène Decaluwe, Christian Beauséjour
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract The potential of immune checkpoint inhibitors (ICI) may be limited in situations where immune cell fitness is impaired. Here, we show that the efficacy of cancer immunotherapies is compromised by the accumulation of senescent cells in mice a
Externí odkaz:
https://doaj.org/article/6176530a4d9a475d942f002aa1f6fc5f
Autor:
Marie-Eve Bordeleau, Éric Audemard, Arnaud Métois, Louis Theret, Véronique Lisi, Azer Farah, Jean-François Spinella, Jalila Chagraoui, Ossama Moujaber, Léo Aubert, Banafsheh Khakipoor, Laure Mallinger, Isabel Boivin, Nadine Mayotte, Azadeh Hajmirza, Éric Bonneil, François Béliveau, Sybille Pfammatter, Albert Feghaly, Geneviève Boucher, Patrick Gendron, Pierre Thibault, Frédéric Barabé, Sébastien Lemieux, Guillaume Richard-Carpentier, Josée Hébert, Vincent-Philippe Lavallée, Philippe P. Roux, Guy Sauvageau
Publikováno v:
Cell Reports, Vol 43, Iss 6, Pp 114260- (2024)
Summary: Immunotherapy remains underexploited in acute myeloid leukemia (AML) compared to other hematological malignancies. Currently, gemtuzumab ozogamicin is the only therapeutic antibody approved for this disease. Here, to identify potential targe
Externí odkaz:
https://doaj.org/article/8cf475f1511748f0b536ab3c7b29e97a
Autor:
Nicolas Poirier, Elie Haddad, Michel Duval, Valérie Paquin, Séverine Leclerc, Véronique Lisi, Carolina Marmolejo, Hicham Affia, Paulo Cordeiro, Yves Théorêt, Gregor Andelfinger, Vincent Philippe Lavallée, Sabine Herblot
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 12, Iss 5 (2024)
Background Allogeneic hematopoietic stem cell transplantation (HSCT) remains the standard of care for chemotherapy-refractory leukemia patients, but cure rates are still dismal. To prevent leukemia relapse following HSCT, we aim to improve the early
Externí odkaz:
https://doaj.org/article/f0f0716f6dc24b4b8ba472b368e8d196
Autor:
Marie-Lyn Goyer, Cynthia Desaulniers-Langevin, Anthony Sonn, Georgio Mansour Nehmo, Véronique Lisi, Basma Benabdallah, Noël J.-M. Raynal, Christian Beauséjour
Publikováno v:
Cells, Vol 13, Iss 10, p 849 (2024)
The risk of aberrant growth of induced pluripotent stem cell (iPSC)-derived cells in response to DNA damage is a potential concern as the tumor suppressor genes TP53 and CDKN2A are transiently inactivated during reprogramming. Herein, we evaluate the
Externí odkaz:
https://doaj.org/article/b05aeb8b457a46348ea195e1c8cc302c
Autor:
Shirin Lak, Valérie Janelle, Anissa Djedid, Gabrielle Boudreau, Ann Brasey, Véronique Lisi, Ali Smaani, Cédric Carli, Lambert Busque, Vincent-Philippe Lavallée, Jean-Sébastien Delisle
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 27, Iss , Pp 230-245 (2022)
Antigen-specific T cell expansion ex vivo followed by adoptive transfer enables targeting of a multitude of microbial and cancer antigens. However, clinical-scale T cell expansion from rare precursors requires repeated stimulation, which may lead to
Externí odkaz:
https://doaj.org/article/69663426dd644361ad6f2f2b985cbce2
Autor:
Edouard Charlebois, Carine Fillebeen, John Presley, Gael Cagnone, Véronique Lisi, Vincent-Philippe Lavallée, Jean-Sébastien Joyal, Kostas Pantopoulos
Publikováno v:
Blood. 141:271-284
Homeostatic adaptation to systemic iron overload involves transcriptional induction of bone morphogenetic protein 6 (BMP6) in liver sinusoidal endothelial cells (LSECs). BMP6 is then secreted to activate signaling of the iron hormone hepcidin (HAMP)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa0b884aca24e206dfffb07ce1b742db
https://doi.org/10.1182/blood.2022016987
https://doi.org/10.1182/blood.2022016987
Autor:
Véronique Lisi, Ève Blanchard, Michael Vladovsky, Éric Audemard, Albert Ferghaly, Sébastien Lemieux, Josée Hébert, Guy Sauvageau, Vincent-Philippe Lavallée
Publikováno v:
Blood Advances. 6:5160-5164
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::902bdab8794ae5fa6eb6892aadec7711
https://doi.org/10.1182/bloodadvances.2022007300
https://doi.org/10.1182/bloodadvances.2022007300
Autor:
Véronique Lisi, Bhagat Singh, Michel Giroux, Elmer Guzman, Michio W. Painter, Yung-Chih Cheng, Eric Huebner, Giovanni Coppola, Michael Costigan, Clifford J. Woolf, Kenneth S. Kosik
Publikováno v:
Cell Reports, Vol 20, Iss 5, Pp 1136-1147 (2017)
Summary: Peripheral nerve regeneration after injury requires a broad program of transcriptional changes. We investigated the basis for the enhanced nerve regenerative capacity of the CAST/Ei mouse strain relative to C57BL/6 mice. RNA sequencing of do
Externí odkaz:
https://doaj.org/article/a39f43325083432fa937c1852723fffe
Autor:
Nada Jabado, Claudia L. Kleinman, Livia Garzia, Michael D. Taylor, Stephen C. Mack, Benjamin A. Garcia, Peter W. Lewis, Pierre Thibault, Jay S. Wunder, Robert Turcotte, Brendan C. Dickson, Jason Karamchandani, Sungmi Jung, Ashot S. Harutyunyan, Véronique Lisi, Robert Eveleigh, Tianna S. Sihota, Kateryna Rossokhata, Siddhant U. Jain, Takeaki Ishii, Éric Bonneil, Joel Lanoix, Dylan M. Marchione, Damien Faury, Leonie G. Mikael, Carol C.L. Chen, Wajih Jawhar, Liam D. Hendrikse, Shriya Deshmukh, Nicolas De Jay, Sima Khazaei
Differential Expression in Isogenic Lines
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1343050be4db44fce4eca262d777317
https://doi.org/10.1158/2159-8290.22535012
https://doi.org/10.1158/2159-8290.22535012
Autor:
Nada Jabado, Claudia L. Kleinman, Livia Garzia, Michael D. Taylor, Stephen C. Mack, Benjamin A. Garcia, Peter W. Lewis, Pierre Thibault, Jay S. Wunder, Robert Turcotte, Brendan C. Dickson, Jason Karamchandani, Sungmi Jung, Ashot S. Harutyunyan, Véronique Lisi, Robert Eveleigh, Tianna S. Sihota, Kateryna Rossokhata, Siddhant U. Jain, Takeaki Ishii, Éric Bonneil, Joel Lanoix, Dylan M. Marchione, Damien Faury, Leonie G. Mikael, Carol C.L. Chen, Wajih Jawhar, Liam D. Hendrikse, Shriya Deshmukh, Nicolas De Jay, Sima Khazaei
Glycine 34-to-tryptophan (G34W) substitutions in H3.3 arise in approximately 90% of giant cell tumor of bone (GCT). Here, we show H3.3 G34W is necessary for tumor formation. By profiling the epigenome, transcriptome, and secreted proteome of patient
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::240c3963b5983b5d16a4ad808d771db7
https://doi.org/10.1158/2159-8290.c.6547733.v1
https://doi.org/10.1158/2159-8290.c.6547733.v1