Zobrazeno 1 - 10
of 166
pro vyhledávání: '"Véronique, Lindner"'
Autor:
Hélène Lê, Jules Deforges, Pasquale Cutolo, Anissa Lamarque, Guoqiang Hua, Véronique Lindner, Shreyansh Jain, Jean-Marc Balloul, Nadia Benkirane-Jessel, Eric Quéméneur
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Onco-virotherapy is an emergent treatment for cancer based on viral vectors. The therapeutic activity is based on two different mechanisms including tumor-specific oncolysis and immunostimulatory properties. In this study, we evaluated onco-virothera
Externí odkaz:
https://doaj.org/article/6c17b8192e2d4ef1ad592594a56141d4
Autor:
Xiaoping Su, Xiaofan Lu, Sehrish Khan Bazai, Linda Dainese, Arnauld Verschuur, Benoit Dumont, Roger Mouawad, Li Xu, Wenxuan Cheng, Fangrong Yan, Sabine Irtan, Véronique Lindner, Catherine Paillard, Yves Le Bouc, Aurore Coulomb, Gabriel G. Malouf
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
Abstract Wilms tumors are highly curable in up to 90% of cases with a combination of surgery and radio-chemotherapy, but treatment-resistant types such as diffuse anaplastic Wilms tumors pose significant therapeutic challenges. Our multi-omics profil
Externí odkaz:
https://doaj.org/article/04f4843568a140c78ff076e8570ab074
Autor:
Bujamin H. Vokshi, Guillaume Davidson, Nassim Tawanaie Pour Sedehi, Alexandra Helleux, Marc Rippinger, Alexandre R. Haller, Justine Gantzer, Jonathan Thouvenin, Philippe Baltzinger, Rachida Bouarich, Valeria Manriquez, Sakina Zaidi, Priya Rao, Pavlos Msaouel, Xiaoping Su, Hervé Lang, Thibault Tricard, Véronique Lindner, Didier Surdez, Jean-Emmanuel Kurtz, Franck Bourdeaut, Nizar M. Tannir, Irwin Davidson, Gabriel G. Malouf
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-19 (2023)
Abstract Renal medullary carcinoma (RMC) is an aggressive tumour driven by bi-allelic loss of SMARCB1 and tightly associated with sickle cell trait. However, the cell-of-origin and oncogenic mechanism remain poorly understood. Using single-cell seque
Externí odkaz:
https://doaj.org/article/01f90a34514d4d2a88792568e2a609ad
Autor:
Hélène Lê, Jules Deforges, Guoqiang Hua, Ysia Idoux-Gillet, Charlotte Ponté, Véronique Lindner, Anne Olland, Pierre-Emanuel Falcoz, Cécile Zaupa, Shreyansh Jain, Eric Quéméneur, Nadia Benkirane-Jessel, Jean-Marc Balloul
Publikováno v:
iScience, Vol 26, Iss 10, Pp 108094- (2023)
Summary: This work describes a patient-derived tumoroid model (PDTs) to support precision medicine in lung oncology. The use of human adipose tissue-derived microvasculature and patient-derived peripheral blood mononuclear cells (PBMCs) permits to ac
Externí odkaz:
https://doaj.org/article/f04495021d784eabb48ecdf7bddeee29
Autor:
Claire Béraud, Nadege Bidan, Myriam Lassalle, Hervé Lang, Véronique Lindner, Clémentine Krucker, Julien Masliah-Planchon, Eric Potiron, Philippe Lluel, Thierry Massfelder, Yves Allory, Yolande Misseri
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
BackgroundDespite the significant advances in the management of advanced prostate cancer (PCa), metastatic PCa is currently considered incurable. For further investigations in precision treatment, the development of preclinical models representing th
Externí odkaz:
https://doaj.org/article/b98cdf9241d943d58e20b5feeffc4c38
Autor:
Hervé Lang, Claire Béraud, Luc Cabel, Jacqueline Fontugne, Myriam Lassalle, Clémentine Krucker, Florent Dufour, Clarice S. Groeneveld, Victoria Dixon, Xiangyu Meng, Aurélie Kamoun, Elodie Chapeaublanc, Aurélien De Reynies, Xavier Gamé, Pascal Rischmann, Ivan Bieche, Julien Masliah-Planchon, Romane Beaurepere, Yves Allory, Véronique Lindner, Yolande Misseri, François Radvanyi, Philippe Lluel, Isabelle Bernard-Pierrot, Thierry Massfelder
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
BackgroundMuscle-invasive bladder cancer (MIBC) and upper urinary tract urothelial carcinoma (UTUC) are molecularly heterogeneous. Despite chemotherapies, immunotherapies, or anti-fibroblast growth factor receptor (FGFR) treatments, these tumors are
Externí odkaz:
https://doaj.org/article/530d7616638a4e26a742ecd5e89e062d
Autor:
Anasse Nounsi, Joseph Seitlinger, Charlotte Ponté, Julien Demiselle, Ysia Idoux-Gillet, Erwan Pencreach, Michèle Beau-Faller, Véronique Lindner, Jean-Marc Balloul, Eric Quemeneur, Hélène Burckel, Georges Noël, Anne Olland, Florence Fioretti, Pierre-Emmanuel Falcoz, Nadia Benkirane-Jessel, Guoqiang Hua
Publikováno v:
Biomedicines, Vol 11, Iss 7, p 1824 (2023)
Radiation therapy and platinum-based chemotherapy are common treatments for lung cancer patients. Several factors are considered for the low overall survival rate of lung cancer, such as the patient’s physical state and the complex heterogeneity of
Externí odkaz:
https://doaj.org/article/dbd8ffc5895445ddb7df859cf885a4d9
Autor:
Hélène Lê, Joseph Seitlinger, Véronique Lindner, Anne Olland, Pierre-Emmanuel Falcoz, Nadia Benkirane-Jessel, Eric Quéméneur
Publikováno v:
Biomedicines, Vol 10, Iss 7, p 1677 (2022)
Synthetic 3D multicellular systems derived from patient tumors, or tumoroids, have been developed to complete the cancer research arsenal and overcome the limits of current preclinical models. They aim to represent the molecular and structural hetero
Externí odkaz:
https://doaj.org/article/c3df88754f3f4a08bd961c22095de7e8
Vascularization of Patient-Derived Tumoroid from Non-Small-Cell Lung Cancer and Its Microenvironment
Autor:
Joseph Seitlinger, Anasse Nounsi, Ysia Idoux-Gillet, Eloy Santos Pujol, Hélène Lê, Erwan Grandgirard, Anne Olland, Véronique Lindner, Cécile Zaupa, Jean-Marc Balloul, Eric Quemeneur, Gilbert Massard, Pierre-Emmanuel Falcoz, Guoqiang Hua, Nadia Benkirane-Jessel
Publikováno v:
Biomedicines, Vol 10, Iss 5, p 1103 (2022)
Patient-derived tumoroid (PDT) has been developed and used for anti-drug screening in the last decade. As compared to other existing drug screening models, a PDT-based in vitro 3D cell culture model could preserve the histological and mutational char
Externí odkaz:
https://doaj.org/article/92b5010fc69742e8b872ff76c7d08ea7
Autor:
Xiaofan Lu, Yann Vano, Alexandra Helleux, Xiaoping Su, Véronique Lindner, Guillaume Davidson, Roger Mouawad, Jean-Philippe Spano, Morgan Rouprêt, Reza Elaidi, Eva Compérat, Virginie Verkarre, Chengming Sun, Christine Chevreau, Mostefa Bennamoun, Hervé Lang, Thibault Tricard, Wenxuan Cheng, Li Xu, Irwin Davidson, Fangrong Yan, Wolf Herman Fridman, Catherine Sautes-Fridman, Stéphane Oudard, Gabriel G. Malouf
Publikováno v:
Clinical Cancer Research. 29:1279-1291
Purpose: Immune checkpoint inhibitors (ICI) have revolutionized the treatment of patients with clear-cell renal cell carcinomas (ccRCC). Although analyses of transcriptome, genetic alterations, and the tumor microenvironment (TME) have shed light int
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0e11c3eb95ae69ab3ce70e784a420aa
https://doi.org/10.1158/1078-0432.ccr-22-2133
https://doi.org/10.1158/1078-0432.ccr-22-2133