Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Väyrynen, J. P. (Juha P.)"'
Autor:
Väyrynen, J. P. (Juha P.), Haruki, K. (Koichiro), Lau, M. C. (Mai Chan), Väyrynen, S. A. (Sara A.), Ugai, T. (Tomotaka), Akimoto, N. (Naohiko), Zhong, R. (Rong), Zhao, M. (Melissa), Costa, A. D. (Andressa Dias), Borowsky, J. (Jennifer), Bell, P. (Phoenix), Takashima, Y. (Yasutoshi), Fujiyoshi, K. (Kenji), Arima, K. (Kota), Kishikawa, J. (Junko), Shi, S.-s. (Shan-shan), Twombly, T. S. (Tyler S.), Song, M. (Mingyang), Wu, K. (Kana), Chan, A. T. (Andrew T.), Zhang, X. (Xuehong), Fuchs, C. S. (Charles S.), Meyerhardt, J. A. (Jeffrey A.), Giannakis, M. (Marios), Ogino, S. (Shuji), Nowak, J. A. (Jonathan A.)
Although tumor-infiltrating T cells hold a beneficial prognostic role in colorectal cancer, other lymphocytic populations are less characterized. We developed a multiplexed immunofluorescence assay coupled with digital image analysis and machine lear
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______2423::92b4cc5b1d745bf82879356d0eb7f319
http://urn.fi/urn:nbn:fi-fe202201199473
http://urn.fi/urn:nbn:fi-fe202201199473
Autor:
Honkanen, T. J. (Tiia J.), Luukkainen, M. E. (Milla E. K.), Tikkanen, A. (Antti), Karihtala, P. (Peeter), Mäkinen, M. (Markus), Väyrynen, J. P. (Juha P.), Koivunen, J. P. (Jussi P.)
Purpose: Recent works have characterized that metastatic site can affect the tumour immune profiles and efficiency of cancer immunotherapies. The prognosis of HER2-positive breast cancer is associated with the characteristics of the tumour immune mic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______2423::85cad544f842d88d27228ac1399e83db
http://urn.fi/urn:nbn:fi-fe2022030922640
http://urn.fi/urn:nbn:fi-fe2022030922640
Autor:
Borowsky, J. (Jennifer), Haruki, K. (Koichiro), Lau, M. C. (Mai Chan), Costa, A. D. (Andressa Dias), Väyrynen, J. P. (Juha P.), Ugai, T. (Tomotaka), Arima, K. (Kota), da Silva, A. (Annacarolina), Felt, K. D. (Kristen D.), Zhao, M. (Melissa), Gurjao, C. (Carino), Twombly, T. S. (Tyler S.), Fujiyoshi, K. (Kenji), Väyrynen, S. A. (Sara A.), Hamada, T. (Tsuyoshi), Mima, K. (Kosuke), Bullman, S. (Susan), Harrison, T. A. (Tabitha A.), Phipps, A. I. (Amanda I.), Peters, U. (Ulrike), Ng, K. (Kimmie), Meyerhardt, J. A. (Jeffrey A.), Song, M. (Mingyang), Giovannucci, E. L. (Edward L.), Wu, K. (Kana), Zhang, X. (Xuehong), Freeman, G. J. (Gordon J.), Huttenhower, C. (Curtis), Garrett, W. S. (Wendy S.), Chan, A. T. (Andrew T.), Leggett, B. A. (Barbara A.), Whitehall, V. L. (Vicki L. J.), Walker, N. (Neal), Brown, I. (Ian), Bettington, M. (Mark), Nishihara, R. (Reiko), Fuchs, C. S. (Charles S.), Lennerz, J. K. (Jochen K.), Giannakis, M. (Marios), Nowak, J. A. (Jonathan A.), Ogino, S. (Shuji)
Purpose: While evidence indicates that Fusobacterium nucleatum (F. nucleatum) may promote colorectal carcinogenesis through its suppressive effect on T-cell–mediated antitumor immunity, the specific T-cell subsets involved remain uncertain. Experim
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______2423::af700ce14932447ea248f6c498f65da7
http://urn.fi/urn:nbn:fi-fe2021042611954
http://urn.fi/urn:nbn:fi-fe2021042611954
Autor:
Ahtiainen, M. (Maarit), Elomaa, H. (Hanna), Väyrynen, J. P. (Juha P.), Wirta, E.-V. (Erkki-Ville), Kuopio, T. (Teijo), Helminen, O. (Olli), Seppälä, T. T. (Toni T.), Kellokumpu, I. (Ilmo), Mecklin, J.-P. (Jukka-Pekka)
Purpose: To evaluate immune cell infiltration, the programmed death-1/programmed death ligand-1 (PD-1/PD-L1) expression and their prognostic value in a series of mismatch proficient (pMMR) CRC with matched liver and lung metastases. Methods: Formalin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______2423::ded8572a9915ef976df4b46b3840030d
http://urn.fi/urn:nbn:fi-fe2021041910934
http://urn.fi/urn:nbn:fi-fe2021041910934
Autor:
Sirniö, P. (Päivi), Väyrynen, J. P. (Juha P.), Mutt, S. J. (Shivaprakash J.), Herzig, K.-H. (Karl-Heinz), Walkowiak, J. (Jaroslaw), Klintrup, K. (Kai), Mäkelä, J. (Jyrki), Karttunen, T. J. (Tuomo J.), Mäkinen, M. J. (Markus J.), Tuomisto, A. (Anne)
Systemic inflammation is a stage-independent marker of poor prognosis in colorectal cancer (CRC), activated in a complex, multifactorial process. It has been proposed that one of the main factors driving systemic inflammation may be tumor necrosis. K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______2423::b644fa729c521f369386f253062f8452
http://urn.fi/urn:nbn:fi-fe2020082864577
http://urn.fi/urn:nbn:fi-fe2020082864577
Autor:
Patankar, M. (Madhura), Mattila, T. (Taneli), Väyrynen, J. P. (Juha P.), Klintrup, K. (Kai), Mäkelä, J. (Jyrki), Tuomisto, A. (Anne), Nieminen, P. (Pentti), Mäkinen, M. J. (Markus J.), Karttunen, T. J. (Tuomo J.)
Anoikis is a form of apoptosis induced when a cell loses contact with the extracellular matrix (ECM). Anoikis resistance is essential for metastasis formation, yet only detectable by in vitro experiments. We present a method for quantitation of putat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______2423::5c025cd9a788e0fe516013d22f87c25a
http://urn.fi/urn:nbn:fi-fe2020063046398
http://urn.fi/urn:nbn:fi-fe2020063046398
Autor:
Sirniö, P. (Päivi), Väyrynen, J. P. (Juha P.), Klintrup, K. (Kai), Mäkelä, J. (Jyrki), Karhu, T. (Toni), Herzig, K.-H. (Karl-Heinz), Minkkinen, I. (Ilkka), Mäkinen, M. J. (Markus J.), Karttunen, T. J. (Tuomo J.), Tuomisto, A. (Anne)
Background: Cancer cachexia is a complex wasting syndrome affecting patients with advanced cancer, with systemic inflammation as a key component in pathogenesis. Protein degradation and release of amino acids (AAs) in skeletal muscle are stimulated i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______2423::b6a478873e91701ebf2396ead2a1ded0
http://urn.fi/urn:nbn:fi-fe202002216172
http://urn.fi/urn:nbn:fi-fe202002216172
Autor:
Tuomisto, A. (Anne), Nørskov, N. P. (Natalja P.), Sirniö, P. (Päivi), Väyrynen, J. P. (Juha P.), Mutt, S. J. (Shivaprakash J.), Klintrup, K. (Kai), Mäkelä, J. (Jyrki), Knudsen, K. E. (Knud Erik Bach), Mäkinen, M. J. (Markus J.), Herzig, K.-H. (Karl-Heinz)
The dietary lignan metabolite, enterolactone, has been suggested to have anti-cancer functions, and high serum enterolactone concentrations have been associated with decreased risk of breast and prostate cancers. We hypothesized that serum enterolact
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______2423::3fc77c75df689f40561401a643265cd9
http://urn.fi/urn:nbn:fi-fe2019082024792
http://urn.fi/urn:nbn:fi-fe2019082024792
Autor:
Väyrynen, J. P. (Juha P.), Tuomisto, A. (Anne), Väyrynen, S. A. (Sara A.), Klintrup, K. (Kai), Karhu, T. (Toni), Mäkelä, J. (Jyrki), Herzig, K.-H. (Karl-Heinz), Karttunen, T. J. (Tuomo J.), Mäkinen, M. J. (Markus J.)
Anemia is common in colorectal cancer (CRC) but its relationships with tumor characteristics, systemic inflammation, and survival have not been well characterized. In this study, blood hemoglobin levels and erythrocyte mean corpuscular volume (MCV) l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______2423::77c948f480b6349815d038ab263eda66
http://urn.fi/urn:nbn:fi-fe201804096392
http://urn.fi/urn:nbn:fi-fe201804096392