A "spindle and thread" mechanism unblocks p53 translation by modulating N-terminal disorder.

Autor: Kaldmäe M; Department of Microbiology, Tumor and Cell Biology, Karolinska Institutet - Biomedicum, Solnavägen 9, 17165 Solna, Sweden. Electronic address: Margit.Kaldmae@ki.se., Vosselman T; Department of Microbiology, Tumor and Cell Biology, Karolinska Institutet - Biomedicum, Solnavägen 9, 17165 Solna, Sweden., Zhong X; Department of Biomedical Engineering and Health Systems, School of Engineering Sciences in Chemistry, Biotechnology and Health (CBH), KTH Royal Institute of Technology, 141 83 Huddinge, Sweden., Lama D; Department of Microbiology, Tumor and Cell Biology, Karolinska Institutet - Biomedicum, Solnavägen 9, 17165 Solna, Sweden., Chen G; Department of Biosciences and Nutrition, Karolinska Institutet, 148 13 Huddinge, Sweden., Saluri M; Department of Microbiology, Tumor and Cell Biology, Karolinska Institutet - Biomedicum, Solnavägen 9, 17165 Solna, Sweden; School of Natural Sciences and Health, Tallinn University, Narva mnt 25, 10120 Tallinn, Estonia., Kronqvist N; Department of Biosciences and Nutrition, Karolinska Institutet, 148 13 Huddinge, Sweden., Siau JW; Disease Intervention Technology Laboratory, Institute of Molecular and Cell Biology, A(∗)STAR, 8A Biomedical Grove #06-06 Immunos, Singapore 138648, Singapore., Ng AS; Disease Intervention Technology Laboratory, Institute of Molecular and Cell Biology, A(∗)STAR, 8A Biomedical Grove #06-06 Immunos, Singapore 138648, Singapore., Ghadessy FJ; Disease Intervention Technology Laboratory, Institute of Molecular and Cell Biology, A(∗)STAR, 8A Biomedical Grove #06-06 Immunos, Singapore 138648, Singapore., Sabatier P; Division of Physiological Chemistry I, Department of Medical Biochemistry and 5 Biophysics, Karolinska Institutet - Biomedicum, Solnavägen 9, 17165 Solna, Sweden., Vojtesek B; Masaryk Memorial Cancer Institute, RECAMO, Zluty kopec 7, 656 53 Brno, Czech Republic., Sarr M; Department of Biosciences and Nutrition, Karolinska Institutet, 148 13 Huddinge, Sweden., Sahin C; Department of Microbiology, Tumor and Cell Biology, Karolinska Institutet - Biomedicum, Solnavägen 9, 17165 Solna, Sweden., Österlund N; Department of Biochemistry and Biophysics, Stockholm University, 10691 Stockholm, Sweden., Ilag LL; Department of Materials and Environmental Chemistry, Stockholm University, 10691 Stockholm, Sweden., Väänänen VA; Department of Microbiology, Tumor and Cell Biology, Karolinska Institutet - Biomedicum, Solnavägen 9, 17165 Solna, Sweden., Sedimbi S; Department of Microbiology, Tumor and Cell Biology, Karolinska Institutet - Biomedicum, Solnavägen 9, 17165 Solna, Sweden., Arsenian-Henriksson M; Department of Microbiology, Tumor and Cell Biology, Karolinska Institutet - Biomedicum, Solnavägen 9, 17165 Solna, Sweden., Zubarev RA; Division of Physiological Chemistry I, Department of Medical Biochemistry and 5 Biophysics, Karolinska Institutet - Biomedicum, Solnavägen 9, 17165 Solna, Sweden; Department of Pharmacological & Technological Chemistry, I.M. Sechenov First Moscow State Medical University, Moscow, 119146, Russia; The National Medical Research Center for Endocrinology, 115478 Moscow, Russia., Nilsson L; Department of Biosciences and Nutrition, Karolinska Institutet, 148 13 Huddinge, Sweden., Koeck PJB; Department of Biomedical Engineering and Health Systems, School of Engineering Sciences in Chemistry, Biotechnology and Health (CBH), KTH Royal Institute of Technology, 141 83 Huddinge, Sweden; Department of Biosciences and Nutrition, Karolinska Institutet, 148 13 Huddinge, Sweden., Rising A; Department of Biosciences and Nutrition, Karolinska Institutet, 148 13 Huddinge, Sweden; Department of Anatomy, Physiology and Biochemistry, Swedish University of Agricultural Sciences, Box 7011, Uppsala 750 07, Sweden., Abelein A; Department of Biosciences and Nutrition, Karolinska Institutet, 148 13 Huddinge, Sweden., Fritz N; Department of Microbiology, Tumor and Cell Biology, Karolinska Institutet - Biomedicum, Solnavägen 9, 17165 Solna, Sweden., Johansson J; Department of Biosciences and Nutrition, Karolinska Institutet, 148 13 Huddinge, Sweden. Electronic address: Janne.Johansson@ki.se., Lane DP; Department of Microbiology, Tumor and Cell Biology, Karolinska Institutet - Biomedicum, Solnavägen 9, 17165 Solna, Sweden., Landreh M; Department of Microbiology, Tumor and Cell Biology, Karolinska Institutet - Biomedicum, Solnavägen 9, 17165 Solna, Sweden. Electronic address: Michael.Landreh@ki.se.

Publikováno v: Structure (London, England : 1993) [Structure] 2022 May 05; Vol. 30 (5), pp. 733-742.e7. Date of Electronic Publication: 2022 Mar 14.