Výsledky vyhledávání - "Vân Anh Huynh-Thu"

Akademický článek

Mapping Gene Regulatory Networks in Drosophila Eye Development by Large-Scale Transcriptome Perturbations and Motif Inference

Autor: Delphine Potier, Kristofer Davie, Gert Hulselmans, Marina Naval Sanchez, Lotte Haagen, Vân Anh Huynh-Thu, Duygu Koldere, Arzu Celik, Pierre Geurts, Valerie Christiaens, Stein Aerts

Publikováno v: Cell Reports, Vol 9, Iss 6, Pp 2290-2303 (2014)

Genome control is operated by transcription factors (TFs) controlling their target genes by binding to promoters and enhancers. Conceptually, the interactions between TFs, their binding sites, and their functional targets are represented by gene regu

Externí odkaz: https://doaj.org/article/8692b193e7d141399ca4c856f3f95f0c

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Akademický článek

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Discovery of biomarker candidates associated with the risk of short-term and mid/long-term relapse after infliximab withdrawal in Crohn’s patients: a proteomics-based study

Autor: Dominique Baiwir, Edwin De Pauw, Nicolas Pierre, Marie-Alice Meuwis, D. Laharie, Yoram Bouhnik, Edouard Louis, Vân Anh Huynh-Thu, Gabriel Mazzucchelli, Nicolas Smargiasso, Jean-Frederic Colombel

Publikováno v: Gut. 70:1450-1457

ObjectiveA subset of Crohn’s disease (CD) patients experiences mid/long-term remission after infliximab withdrawal. Biomarkers are needed to identify those patients.DesignNew biomarkers of relapse were searched in the baseline serum of CD patients

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a85429aa4020d67a91dc7821e32b4476
https://doi.org/10.1136/gutjnl-2020-322100

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OP12 Blood proteins related to immunoregulation or cellular junctions reveal distinct biological profiles associated with the risk of short-term versus mid/long-term relapse in Crohn’s Disease patients stopping infliximab

Autor: Edouard Louis, Nicolas Pierre, Mathieu Allez, Marie-Alice Meuwis, Y. Bouhnik, D. Laharie, Arnaud Bourreille, J.-F. Colombel, Vân Anh Huynh-Thu

Publikováno v: Journal of Crohn's and Colitis. 15:S011-S013

Background In Crohn’s disease (CD), biologics can induce mucosal healing and stable remission. After reaching this target, treatment de-escalation could be considered but the risk of relapse needs to be estimated. Current biomarkers used to predict

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::1e69e826d9aa93bc39e02d1a26da4cf1
https://doi.org/10.1093/ecco-jcc/jjab075.011

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Akademický článek

NIMEFI: gene regulatory network inference using multiple ensemble feature importance algorithms.

Autor: Joeri Ruyssinck, Vân Anh Huynh-Thu, Pierre Geurts, Tom Dhaene, Piet Demeester, Yvan Saeys

Publikováno v: PLoS ONE, Vol 9, Iss 3, p e92709 (2014)

One of the long-standing open challenges in computational systems biology is the topology inference of gene regulatory networks from high-throughput omics data. Recently, two community-wide efforts, DREAM4 and DREAM5, have been established to benchma

Externí odkaz: https://doaj.org/article/1003171ba3b04017858801a530216305

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Nets Versus Trees for Feature Ranking and Gene Network Inference

Autor: Pierre Geurts, Jean-Michel Begon, Antonio Sutera, Nicolas Vecoven, Vân Anh Huynh-Thu

Publikováno v: Discovery Science ISBN: 9783030615260
DS

We investigate several global variable importance measures derived from artificial neural networks (ANN) to address the challenging problem of feature ranking in high-dimensional unstructured problems. While several ANN (local) importance measures ha

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::cddff012e55227cba2bc99aa4d1c9dc0
https://doi.org/10.1007/978-3-030-61527-7_16

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Akademický článek

Myelin-derived lipids modulate macrophage activity by liver X receptor activation.

Autor: Jeroen F J Bogie, Silke Timmermans, Vân Anh Huynh-Thu, Alexandre Irrthum, Hubert J M Smeets, Jan-Åke Gustafsson, Knut R Steffensen, Monique Mulder, Piet Stinissen, Niels Hellings, Jerome J A Hendriks

Publikováno v: PLoS ONE, Vol 7, Iss 9, p e44998 (2012)

Multiple sclerosis is a chronic, inflammatory, demyelinating disease of the central nervous system in which macrophages and microglia play a central role. Foamy macrophages and microglia, containing degenerated myelin, are abundantly found in active

Externí odkaz: https://doaj.org/article/5aafb65e5a5b4dbea6049ae2cc79c7b5

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Akademický článek

MicroRNAs profiling in murine models of acute and chronic asthma: a relationship with mRNAs targets.

Autor: Nancy Garbacki, Emmanuel Di Valentin, Vân Anh Huynh-Thu, Pierre Geurts, Alexandre Irrthum, Céline Crahay, Thierry Arnould, Christophe Deroanne, Jacques Piette, Didier Cataldo, Alain Colige

Publikováno v: PLoS ONE, Vol 6, Iss 1, p e16509 (2011)

BACKGROUND: miRNAs are now recognized as key regulator elements in gene expression. Although they have been associated with a number of human diseases, their implication in acute and chronic asthma and their association with lung remodelling have nev

Externí odkaz: https://doaj.org/article/6c43df40ffd64c46bf754e41c6af9a1a

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