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Publikováno v:
Journal of Planar Chromatography – Modern TLC. 21:143-149
A validated reversed-phase thin-layer chromatographic (RPTLC) method is proposed for parallel estimation of the lipophilicity of chemically diverse neutral compounds or weak acids and bases. To cover a wide range of lipophilicity two optimized chroma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::98a56ec5ccbd1535dffb7f6c1dec1f1e
https://doi.org/10.1556/jpc.21.2008.2.12
https://doi.org/10.1556/jpc.21.2008.2.12
Publikováno v:
Amino Acids. 33:709-717
A novel practical method for the synthesis of N-methyl-DL-aspartic acid 1 (NMA) and new syntheses for N-methyl-aspartic acid derivatives are described. NMA 1, the natural amino acid was synthesized by Michael addition of methylamine to dimethyl fumar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e511775bfd1fffcbb4ddd53503fc9fa
https://doi.org/10.1007/s00726-006-0453-4
https://doi.org/10.1007/s00726-006-0453-4
Publikováno v:
Scopus-Elsevier
Some cyclic chalcone analogues [E-2-(X-benzylidene)-1-indanones, -tetralones, and -benzosuberones], on-plate UV light-catalyzed formation of new chromatographic spots, can be observed during thin-layer chromatography (TLC). Gas chromatographic (GC) a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0847db151369f3ab4bba59c7d2653189
https://doi.org/10.1093/chromsci/43.6.289
https://doi.org/10.1093/chromsci/43.6.289
Publikováno v:
Journal of Liquid Chromatography & Related Technologies. 26:2629-2649
Planar chromatography of ecdysteroids is reviewed. Separation of various ecdysteroids is detailed using both straight‐phase and reversed‐phase thin‐layer chromatography (RP‐TLC). The generally used special techniques, such as two‐dimensiona
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d2e1509d4b92e1cd6860a3ceeb78ac47
https://doi.org/10.1081/jlc-120024534
https://doi.org/10.1081/jlc-120024534
Publikováno v:
Archiv der Pharmazie. 333:48-52
Mexiletine (mex) and tocainide (toc) are antiarrhythmic drugs of closely related structure. Several degradation products are formed by interaction with both light and oxidizing agents in the case of mex, and only by oxidants with toc. On the basis of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::140547fd94f4db77e0d598258897fdc7
https://doi.org/10.1002/(sici)1521-4184(200002)333:2/3<48::aid-ardp48>3.0.co
https://doi.org/10.1002/(sici)1521-4184(200002)333:2/3<48::aid-ardp48>3.0.co
Publikováno v:
International Journal of Pharmaceutics. 180:13-22
The lipophilicity of 17 newly synthesized potential NMDA and cholecystokinin antagonist 2-methyl-4-oxo-3H-quinazoline-3-alkyl-carboxylic acid derivatives has been investigated. The apparent partition coefficients of two amphoteric compounds of overla
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0fd70d35fc0917ed1afa099af6a20a6f
https://doi.org/10.1016/s0378-5173(98)00405-0
https://doi.org/10.1016/s0378-5173(98)00405-0
Publikováno v:
Journal of Liquid Chromatography. 13:1485-1497
New imidazoguinazolone derivatives as potential pharmacons, prepared in our laboratory, have been studied by HPLC and TLC methods. As a part of a structure-properties research study (SPR) this paper deals with the relationship between the chemical st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5b03c436cda9851fabc6bfc08d753a5a
https://doi.org/10.1080/01483919008048971
https://doi.org/10.1080/01483919008048971
Publikováno v:
Journal of pharmaceutical and biomedical analysis. 43(4)
Protonation equilibria of N-methyl-D-aspartate (NMDA, a specific glutamate receptor agonist) and its derivatives are characterized at the macroscopic and microscopic levels. (1)H NMR-pH and pH-potentiometric titrations were carried out to determine t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22caedc8e084bda4b33dc89aa82c87c4
https://pubmed.ncbi.nlm.nih.gov/17161575
https://pubmed.ncbi.nlm.nih.gov/17161575
Publikováno v:
Journal of chromatography. A. 996(1-2)
A reversed-phase thin-layer chromatographic method was developed and applied to quantitate the lipophilicity of sparingly water-soluble eburnane alkaloids of therapeutic interest. Our method development included calibration, optimization and validati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c964682b6deb5cd56ee960418adb956
https://pubmed.ncbi.nlm.nih.gov/12830921
https://pubmed.ncbi.nlm.nih.gov/12830921