Zobrazeno 1 - 10
of 92
pro vyhledávání: '"V, Roschke"'
Autor:
Jong-Sung Park, Yumin Oh, Yong Joo Park, Ogyi Park, Hoseong Yang, Stephanie Slania, Laura K. Hummers, Ami A. Shah, Hyoung-Tae An, Jiyeon Jang, Maureen R. Horton, Joseph Shin, Harry C. Dietz, Eric Song, Dong Hee Na, Eun Ji Park, Kwangmeyung Kim, Kang Choon Lee, Viktor V. Roschke, Justin Hanes, Martin G. Pomper, Seulki Lee
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-11 (2019)
Dermal myofibroblasts are responsible for fibrosis development in scleroderma. Here the authors show that a bioengineered recombinant human TRAIL ligand reverses established fibrosis in mouse models of scleroderma by targeting the death receptor 5 an
Externí odkaz:
https://doaj.org/article/aeaf85cf976741ac932eb66d3a30c13f
Autor:
Ilan R. Kirsch, Kristen S. Gelhaus, Anna V. Roschke, David G. Covell, Ruili Huang, Anders Wallqvist
The karyotypic features of cancer cells have not been a particular focus of anticancer drug targeting either as guidance for treatment or as specific drug targets themselves. Cancer cell lines typically have considerable, characteristic, and variable
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c08ce440fdf11ae49179cab924c170d
https://doi.org/10.1158/1535-7163.c.6531978.v1
https://doi.org/10.1158/1535-7163.c.6531978.v1
Autor:
Ilan R. Kirsch, Kristen S. Gelhaus, Anna V. Roschke, David G. Covell, Ruili Huang, Anders Wallqvist
Supplementary Tables A-M from Drugs aimed at targeting characteristic karyotypic phenotypes of cancer cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11cd08cdd5b45d8c2895569500fe4538
https://doi.org/10.1158/1535-7163.22485531
https://doi.org/10.1158/1535-7163.22485531
Autor:
Ester Rozenblum, Jose R Sotelo-Silveira, Gina Y Kim, Jack Y Zhu, Christopher C Lau, Nicole McNeil, Susana Korolevich, Hongling Liao, James M Cherry, David J Munroe, Thomas Ried, Paul S Meltzer, Walter M Kuehl, Anna V Roschke
Publikováno v:
PLoS ONE, Vol 12, Iss 8, p e0182610 (2017)
A new ovarian near-diploid cell line, OVDM1, was derived from a highly aneuploid serous ovarian metastatic adenocarcinoma. A metastatic tumor was obtained from a 47-year-old Ashkenazi Jewish patient three years after the first surgery removed the pri
Externí odkaz:
https://doaj.org/article/dba79d739dea4b88b3e99d1b86610c4c
Autor:
Anna V. Roschke, Oleg K. Glebov, Samir Lababidi, Kristen S. Gehlhaus, John N. Weinstein, Ilan R. Kirsch
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 10, Iss 11, Pp 1222-1230 (2008)
Chromosomal instability—a hallmark of epithelial cancers—is an ongoing process that results in aneuploidy and karyotypic heterogeneity of a cancer cell population. Previously, we stratified cancer cell lines in the NCI-60 drug discovery panel bas
Externí odkaz:
https://doaj.org/article/704a83da020d4d53be9d5910974efe7c
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 4, Iss 1, Pp 19-31 (2002)
Most human tumors and tumor cell lines exhibit numerical and structural chromosomal abnormalities. The goal of this study was to determine the ongoing rates of structural and numerical instability in selected cancer cell lines and to investigate the
Externí odkaz:
https://doaj.org/article/e169b470a8784c7cb079a9ab7bc25a82
Autor:
Anna V Roschke, Ester eRozenblum
Publikováno v:
Frontiers in Oncology, Vol 3 (2013)
Whole chromosomal instability (W-CIN) – unequal chromosome distribution during cell division - is a characteristic feature of a majority of cancer cells distinguishing them from their normal counterparts. The precise molecular mechanisms that may c
Externí odkaz:
https://doaj.org/article/ad09543593a146a4b80a835d1c869e27
Autor:
Kang Choon Lee, Sangjune Kim, Tae In Kam, Shane A. Liddelow, Yunjong Lee, Nayeon Oh, Seung Pil Yun, Xiaobo Mao, Hyejin Park, Saebom Lee, Han Seok Ko, Ben A. Barres, Nikhil Panicker, Daniel An, Yumin Oh, Saurav Brahmachari, Ted M. Dawson, Jun Hee Lee, Viktor V. Roschke, Jong-Sung Park, Yong Joo Park, Dong Hee Na, SangMin Kim, Senthilkumar S. Karuppagounder, Nayoung Alice Kim, Seung-Hwan Kwon, Valina L. Dawson, Manoj Kumar, Dong-Hoon Kim, Sung Ung Kang, Sang Hun Lee, Seulki Lee, Zoltan Mari
Publikováno v:
Nature medicine
Activation of microglia by classical inflammatory mediators can convert astrocytes into a neurotoxic A1 phenotype in a variety of neurological diseases1,2. Development of agents that could inhibit the formation of A1 reactive astrocytes could be used
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81fb21d702e11544bd196504c3a503dc
http://europepmc.org/articles/PMC6039259
http://europepmc.org/articles/PMC6039259
Akademický článek
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Autor:
W. M. Kuehl, Yan W. Asmann, Anna V. Roschke, Peter Leif Bergsagel, Yulia N. Demchenko, Wei Dong Chen
Publikováno v:
Nucleic Acids Research
Using a combination of array comparative genomic hybridization, mate pair and cloned sequences, and FISH analyses, we have identified in multiple myeloma cell lines and tumors a novel and recurrent type of genomic rearrangement, i.e. interchromosomal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::caf1aac0577069393536bbb5f7a2a3bf
https://doi.org/10.1093/nar/gkw527
https://doi.org/10.1093/nar/gkw527